Patents by Inventor Steven P. Tanis

Steven P. Tanis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MultiLigand Agent for Drug Delivery
    Publication number: 20170028074
    Abstract: Described herein is a compound having the structure of formula I, II, or III, wherein R comprises a double stranded RNA molecule, and L1, L2, and L3 independently for each occurrence comprise a ligand selected from the group consisting of a carbohydrate, a cholesteryl, or a peptide; a pharmaceutically accepted salt or pharmaceutical composition thereof; and a method of making the compound.
    Type: Application
    Filed: July 29, 2016
    Publication date: February 2, 2017
    Inventors: Joseph E. Payne, Padmanabh Chivukula, Steven P. Tanis
  • PPAR-SPARING COMPOUNDS FOR THE TREATMENT OF METABOLIC DISEASES
    Publication number: 20160152570
    Abstract: The present invention relates to hydroxamate compounds and pharmaceutical compositions that are useful for treating and/or preventing metabolic inflammation mediated diseases such as diabetes, obesity, hypertension, dyslipidemia, a neurodegenerative disorder (e.g., Alzheimer's disease, Parkinson's disease, or Huntington's disease), or any combination thereof. Moreover, the present invention also provides methods of treatment for these diseases or disorders.
    Type: Application
    Filed: July 21, 2014
    Publication date: June 2, 2016
    Inventors: Steven P. Tanis, Scott D. Larsen, Gerald D. Artman, III, Timothy Parker
  • PPAR-sparing thiazolidinedione salts for the treatment of metabolic diseases
    Patent number: 9126959
    Abstract: The present invention relates to novel salts of thiazolidinediones and other pharmaceutical agents that are useful for treating and/or preventing metabolic diseases (e.g., diabetes, or neurodegenerative diseases (e.g., Alzheimer's Disease).
    Type: Grant
    Filed: October 30, 2014
    Date of Patent: September 8, 2015
    Assignee: Metabolic Solutions Development Company, LLC
    Inventors: Gerard R. Colca, Steven P. Tanis, Scott D. Larsen
  • PPAR-SPARING THIAZOLIDINEDIONE SALTS FOR THE TREATMENT OF METABOLIC DISEASES
    Publication number: 20150051406
    Abstract: The present invention relates to novel salts of thiazolidinediones and other pharmaceutical agents that are useful for treating and/or preventing metabolic diseases (e.g., diabetes, or neurodegenerative diseases (e.g., Alzheimer's Disease).
    Type: Application
    Filed: October 30, 2014
    Publication date: February 19, 2015
    Inventors: Gerard R. Colca, Steven P. Tanis, Scott D. Larsen
  • Synthesis for thiazolidinedione compounds
    Patent number: 8946435
    Abstract: The present invention provides novel methods for synthesizing PPAR? sparing compounds, e.g., thiazolidinediones, that are useful for preventing and/or treating metabolic disorders such as diabetes, obesity, hypertension, and inflammatory diseases.
    Type: Grant
    Filed: September 5, 2014
    Date of Patent: February 3, 2015
    Assignee: Metabolic Solutions Development Company, LLC
    Inventors: Steven P. Tanis, Timothy Parker, Robert C. Gadwood, James R. Zeller, Gerald D. Artman, III, Scott D. Larsen
  • Synthesis for thiazolidinedione compounds
    Patent number: 8937182
    Abstract: The present invention provides novel methods for synthesizing PPAR? sparing compounds, e.g., thiazolidinediones, that are useful for preventing and/or treating metabolic disorders such as diabetes, obesity, hypertension, and inflammatory diseases.
    Type: Grant
    Filed: April 18, 2011
    Date of Patent: January 20, 2015
    Assignee: Metabolic Solutions Development Company, LLC
    Inventors: James R. Zeller, Steven P. Tanis, Scott D. Larsen, Timothy Parker
  • Synthesis for thiazolidinedione compounds
    Patent number: 8933240
    Abstract: The present invention provides novel methods for synthesizing PPAR? sparing compounds, e.g., thiazolidinediones, that are useful for preventing and/or treating metabolic disorders such as diabetes, obesity, hypertension, and inflammatory diseases.
    Type: Grant
    Filed: August 9, 2011
    Date of Patent: January 13, 2015
    Assignee: Metabolic Solutions Development Company, LLC
    Inventors: Steven P. Tanis, Timothy Parker, Robert C. Gadwood, Gerald D. Artman, III, James R. Zeller
  • Synthesis for Thiazolidinedione Compounds
    Publication number: 20140378687
    Abstract: The present invention provides novel methods for synthesizing PPAR? sparing compounds, e.g., thiazolidinediones, that are useful for preventing and/or treating metabolic disorders such as diabetes, obesity, hypertension, and inflammatory diseases.
    Type: Application
    Filed: September 5, 2014
    Publication date: December 25, 2014
    Inventors: Steven P. Tanis, Timothy Parker, Robert C. Gadwood, James R. Zeller, Gerald D. Artman, III, Scott D. Larsen
  • PPAR-sparing thiazolidinedione salts for the treatment of metabolic diseases
    Patent number: 8912335
    Abstract: The present invention relates to novel salts of thiazolidinediones and other pharmaceutical agents that are useful for treating and/or preventing metabolic diseases (e.g., diabetes, or neurodegenerative diseases (e.g., Alzheimer's Disease).
    Type: Grant
    Filed: December 15, 2010
    Date of Patent: December 16, 2014
    Assignee: Metabolic Solutions Development Company, LLC
    Inventors: Gerard R. Colca, Steven P. Tanis, Scott D. Larsen
  • Synthesis for thiazolidinedione compounds
    Patent number: 8895748
    Abstract: The present invention provides novel methods for synthesizing PPAR? sparing compounds, e.g., thiazolidinediones, that are useful for preventing and/or treating metabolic disorders such as diabetes, obesity, hypertension, and inflammatory diseases.
    Type: Grant
    Filed: August 9, 2011
    Date of Patent: November 25, 2014
    Assignee: Metabolic Solutions Development Company, LLC
    Inventors: Steven P. Tanis, Timothy Parker, Robert C. Gadwood, James R. Zeller, Gerald D. Artman, III, Scott D. Larsen
  • NOVEL SYNTHESIS FOR THIAZOLIDINEDIONE COMPOUNDS
    Publication number: 20140018542
    Abstract: The present invention provides novel methods for synthesizing PPAR? sparing compounds, e.g., thiazolidinediones, that are useful for preventing and/or treating metabolic disorders such as diabetes, obesity, hypertension, and inflammatory diseases.
    Type: Application
    Filed: September 20, 2013
    Publication date: January 16, 2014
    Applicant: Metabolic Solutions Development Company, LLC
    Inventors: Timothy Parker, Robert C. Gadwood, Steven P. Tanis, Scott D. Larsen, James R. Zeller
  • NOVEL SYNTHESIS FOR THIAZOLIDINEDIONE COMPOUNDS
    Publication number: 20130211095
    Abstract: The present invention provides novel methods for synthesizing PPAR? sparing compounds, e.g., thiazolidinediones, that are useful for preventing and/or treating metabolic disorders such as diabetes, obesity, hypertension, and inflammatory diseases.
    Type: Application
    Filed: April 18, 2011
    Publication date: August 15, 2013
    Applicant: Metabolic Solutions Development Company, LLC
    Inventors: Timothy Parker, Robert C. Gadwood, Steven P. Tanis, Scott D. Larsen, James R. Zeller
  • SYNTHESIS FOR THIAZOLIDINEDIONE COMPOUNDS
    Publication number: 20130211092
    Abstract: The present invention provides novel methods for synthesizing PPAR? sparing compounds, e.g., thiazolidinediones, that are useful for preventing and/or treating metabolic disorders such as diabetes, obesity, hypertension, and inflammatory diseases.
    Type: Application
    Filed: August 9, 2011
    Publication date: August 15, 2013
    Applicant: METABOLIC SOLUTIONS DEVELOPMENT COMPANY LLC
    Inventors: Steven P. Tanis, Timothy Parker, Robert C. Gadwood, James R. Zeller, Gerald D. Artman, III, Scott D. Larsen
  • NOVEL SYNTHESIS FOR THIAZOLIDINEDIONE COMPOUNDS
    Publication number: 20130204008
    Abstract: The present invention provides novel methods for synthesizing PPAR? sparing compounds, e.g., thiazolidinediones, that are useful for preventing and/or treating metabolic disorders such as diabetes, obesity, hypertension, and inflammatory diseases.
    Type: Application
    Filed: August 9, 2011
    Publication date: August 8, 2013
    Applicant: Metabolic Solutions Development Company, LLC
    Inventors: Steven P. Tanis, Timothy Parker, Robert C. Gadwood, Gerald D. Artman, III, James R. Zeller
  • NOVEL SYNTHESIS FOR THIAZOLIDINEDIONE COMPOUNDS
    Publication number: 20130204004
    Abstract: The present invention provides novel methods for synthesizing PPAR? sparing compounds, e.g., thiazolidinediones, that are useful for preventing and/or treating metabolic disorders such as diabetes, obesity, hypertension, and inflammatory diseases.
    Type: Application
    Filed: April 18, 2011
    Publication date: August 8, 2013
    Applicant: Metabolic Solutions Development Company, LLC
    Inventors: James R. Zeller, Steven P. Tanis, Scott D. Larsen, Timothy Parker
  • PPAR-SPARING THIAZOLIDINEDIONES AND COMBINATIONS FOR THE TREATMENT OF DIABETES MELLITUS AND OTHER METABOLIC DISEASES
    Publication number: 20120322728
    Abstract: The present invention relates to thiazolidinedione analogues and pharmaceutical compositions that are useful for treating and/or preventing diabetes mellitis, optionally in combination with a second treatment. Furthermore, the present invention also provides methods of inducing remission of the symptoms of diabetes mellitis in a patient comprising administering a thiazolidinedione analogue and a GLP-1 agonist.
    Type: Application
    Filed: December 15, 2010
    Publication date: December 20, 2012
    Applicant: Metabolic Solutions Development Company, LLC
    Inventors: Gerard R. Colca, Rolf F. Kletzien, Steven P. Tanis, Scott D. Larsen
  • PPAR-SPARING THIAZOLIDINEDIONES AND COMBINATIONS FOR THE TREATMENT OF OBESITY AND OTHER METABOLIC DISEASES
    Publication number: 20120316138
    Abstract: The present invention relates to thiazolidinedione analogues and pharmaceutical compositions that are useful for treating and/or preventing obesity or diabetes, optionally in combination with a second treatment therapy such a diet restriction or an increase in duration or exertion in physical activity.
    Type: Application
    Filed: December 15, 2010
    Publication date: December 13, 2012
    Applicant: METABOLIC SOLUTIONS DEVELOPMENT COMPANY, LLC
    Inventors: Gerard R. Colca, Rolf F. Kletzien, Steven P. Tanis, Scott D. Larsen
  • PPAR-SPARING THIAZOLIDINEDIONE SALTS FOR THE TREATMENT OF METABOLIC DISEASES
    Publication number: 20120309975
    Abstract: The present invention relates to novel salts of thiazolidinediones and other pharmaceutical agents that are useful for treating and/or preventing metabolic diseases (e.g., diabetes, or neurodegenerative diseases (e.g., Alzheimer's Disease).
    Type: Application
    Filed: December 15, 2010
    Publication date: December 6, 2012
    Applicant: Metabolic Solutions Development Company LLC
    Inventors: Gerard R. Colca, Steven P. Tanis, Scott D. Larsen
  • Process to produce enantiomerically enriched alcohols and amines
    Patent number: 7045646
    Abstract: This invention describes a convenient method for the preparation and use of a ruthenium catalyst for a chiral reduction of ketones and imines.
    Type: Grant
    Filed: March 19, 2004
    Date of Patent: May 16, 2006
    Assignee: Agouron Pharmaceuticals, Inc.
    Inventors: Steven P. Tanis, Bruce Evans
  • 4-oxo-4,7-dihydrofuro[2,3-b]pyridine-5-carboxamide antiviral agents
    Patent number: 6878705
    Abstract: The invention provides a compound of formula I: wherein G, R2, R3, and R4 have any of the values defined in the specification, or a pharmaceutically acceptable salt thereof, as well as processes and intermediates useful for preparing such compounds or salts, and methods of treating a herpesvirus infection using such compounds or salts.
    Type: Grant
    Filed: January 14, 2003
    Date of Patent: April 12, 2005
    Assignee: Pfizer
    Inventors: Michele M. Cudahy, Mark E. Schnute, Steven P. Tanis, William R. Perrault, Paul Matthew Herrinton, Sajiv K. Nair