Patents by Inventor Steven P. Wrenn

Steven P. Wrenn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENCAPSULATION OF MICROBUBBLES WITHIN THE AQUEOUS CORE OF MICROCAPSULES
    Publication number: 20230240977
    Abstract: The present invention includes a construct that comprises at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention also includes a pharmaceutical composition comprising a construct comprising at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention further includes a method of imaging a tissue or organ in a subject, a method of delivering a therapeutic cargo to a tissue or organ in a subject, and a method of treating a disease or disorder in a subject.
    Type: Application
    Filed: February 10, 2023
    Publication date: August 3, 2023
    Inventors: Steven P. Wrenn, Stephen Dicker
  • METHODS OF IMAGING AND DELIVERING THERAPEUTIC AGENTS
    Publication number: 20230211021
    Abstract: The present disclosure provides imaging agents that are useful for the detection and evaluation of heart conditions, such as myocardial infarction. Upon activation, the imaging agents of the present disclosure may be detected using an ultrasound imaging device.
    Type: Application
    Filed: August 10, 2022
    Publication date: July 6, 2023
    Inventors: Steven P. Wrenn, Brett Angel, Andrew Kohut, Aaron Fafarman, Michael Cimorelli
  • Encapsulation of microbubbles within the aqueous core of microcapsules
    Patent number: 11389395
    Abstract: The present invention includes a construct that comprises at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention also includes a pharmaceutical composition comprising a construct comprising at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention further includes a method of imaging a tissue or organ in a subject, a method of delivering a therapeutic cargo to a tissue or organ in a subject, and a method of treating a disease or disorder in a subject.
    Type: Grant
    Filed: May 29, 2020
    Date of Patent: July 19, 2022
    Assignee: Drexel University
    Inventors: Steven P. Wrenn, Stephen Dicker
  • Encapsulation of Microbubbles Within the Aqueous Core of Microcapsules
    Publication number: 20210113455
    Abstract: The present invention includes a construct that comprises at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention also includes a pharmaceutical composition comprising a construct comprising at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention further includes a method of imaging a tissue or organ in a subject, a method of delivering a therapeutic cargo to a tissue or organ in a subject, and a method of treating a disease or disorder in a subject.
    Type: Application
    Filed: May 29, 2020
    Publication date: April 22, 2021
    Inventors: Steven P. WRENN, Stephen DICKER
  • Encapsulation of microbubbles within the aqueous core of microcapsules
    Patent number: 10688040
    Abstract: The present invention includes a construct that comprises at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention also includes a pharmaceutical composition comprising a construct comprising at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention further includes a method of imaging a tissue or organ in a subject, a method of delivering a therapeutic cargo to a tissue or organ in a subject, and a method of treating a disease or disorder in a subject.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: June 23, 2020
    Assignee: Drexel University
    Inventors: Steven P. Wrenn, Stephen Dicker
  • Encapsulation of Microbubbles Within the Aqueous Core of Microcapsules
    Publication number: 20190262260
    Abstract: The present invention includes a construct that comprises at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention also includes a pharmaceutical composition comprising a construct comprising at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention further includes a method of imaging a tissue or organ in a subject, a method of delivering a therapeutic cargo to a tissue or organ in a subject, and a method of treating a disease or disorder in a subject.
    Type: Application
    Filed: March 4, 2019
    Publication date: August 29, 2019
    Applicant: DREXEL UNIVERSITY
    Inventors: Steven P. WRENN, Stephen DICKER
  • Encapsulation of microbubbles within the aqueous core of microcapsules
    Patent number: 10258563
    Abstract: The present invention includes a construct that comprises at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention also includes a pharmaceutical composition comprising a construct comprising at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention further includes a method of imaging a tissue or organ in a subject, a method of delivering a therapeutic cargo to a tissue or organ in a subject, and a method of treating a disease or disorder in a subject.
    Type: Grant
    Filed: April 20, 2010
    Date of Patent: April 16, 2019
    Assignee: Drexel University
    Inventors: Steven P. Wrenn, Stephen Dicker
  • Encapsulation of Microbubbles Within the Aqueous Core of Microcapsules
    Publication number: 20120109045
    Abstract: The present invention includes a construct that comprises at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention also includes a pharmaceutical composition comprising a construct comprising at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention further includes a method of imaging a tissue or organ in a subject, a method of delivering a therapeutic cargo to a tissue or organ in a subject, and a method of treating a disease or disorder in a subject.
    Type: Application
    Filed: April 20, 2010
    Publication date: May 3, 2012
    Inventors: Steven P. Wrenn, Stephen Dicker