Abstract: Provided herein are systems and methods for configuring trace events. A system includes at least one hardware processor coupled to a memory and configured to instantiate a user code runtime to execute user-defined function (UDF) code. The user code runtime is instantiated within a sandbox process of an execution node. An application programming interface (API) call is detected during execution of the UDF code. The API call includes one or more configurations of a trace event. Telemetry information is collected based on the one or more configurations. The telemetry information is associated with the trace event using a telemetry API. The telemetry API corresponds to the API call. The telemetry information is formatted using the telemetry API, to generate structured telemetry information. The at least one hardware processor causes ingestion of the structured telemetry information into an event table.

Abstract: Methods and kits are described for testing for the presence or absence of any fungus in a sample. Examples of fungi that can be detected include, but are not limited to, those belonging to the genera Candida, Aspergillus and Pneumocystis. The methods include obtaining a sample suspected of containing fungal nucleic acid, including at least one universal region of fungal nucleic acid, and testing for the presence or absence in the sample of the at least one universal region of fungal nucleic acid. Samples may be biological or non-biological.

Abstract: This invention relates to methods and compositions comprising antibodies or fragments thereof comprising a targeting ligand and engineered cytotoxic cells comprising a targeting agent specific for the targeting ligand, for use in inducing cytotoxicity in a cancer cell, in delivering a cytotoxic cell to a cancer cell in a subject, and in treating cancer.

Abstract: Disclosed is an execution information sharing system that duplicates execution information to a provider target (and other targets) as it is being loaded to a consumer target. A consumer account of a data sharing platform executes an application shared with it by a provider account of the platform. Consumer and provider configurations indicating consumer and provider targets respectively are generated. The consumer configuration and provider configurations are provided to an event context to generate a first and second event unloaders respectively, wherein the event context maintains a mapping linking both the first event unloader and the second event unloader to the application. In response to receiving execution information from the application, the first event unloader and the second event unloader are retrieved. The execution information is then written to the consumer target and the provider target using the first event unloader and the second event unloader respectively.

Abstract: A rotating cutter apparatus including a housing having a housing interior surface defining a housing bore, a shaft extending through the housing bore such that an annular space is provided between the housing interior surface and the shaft, and at least one cutter carried on the shaft. The shaft is rotatable relative to the housing about a shaft axis. The at least one cutter extends radially toward the housing interior surface and is rotatable relative to the housing about the shaft axis. A method for reducing a size of solid objects contained in a fluid, including providing a rotating cutter apparatus, introducing the fluid containing the solid objects into the rotating cutter apparatus, and rotating a shaft and at least one cutter in order to reduce the size of the solid objects while passing the fluid through the rotating cutter apparatus.

Abstract: This invention relates to methods and compositions comprising antibodies or fragments thereof comprising a targeting ligand and engineered cytotoxic cells comprising a targeting agent specific for the targeting ligand, for use in inducing cytotoxicity in a cancer cell, in delivering a cytotoxic cell to a cancer cell in a subject, and in treating cancer.

Abstract: Methods and kits are described for testing for the presence or absence of any fungus in a sample. Examples of fungi that can be detected include, but are not limited to, those belonging to the genera Candida, Aspergillus and Pneumocystis. The methods include obtaining a sample suspected of containing fungal nucleic acid, including at least one universal region of fungal nucleic acid, and testing for the presence or absence in the sample of the at least one universal region of fungal nucleic acid. Samples may be biological or non-biological.

Abstract: A rotor catch system includes a catch stem having a proximal end coupled to a rotor of a mud motor system and a distal end positioned within a sub housing of a drill string, a catch feature having a top portion and a spindle portion extending from the top portion and coupled to the distal end of the catch stem, a housing catch feature extending radially inward from an inner surface of the sub housing, and a catch bushing positioned between the top portion of the catch feature and the housing catch feature. The housing catch feature restrains axial movement of the catch bushing in the active catch state via contact between the catch bushing and the housing catch feature, and the catch bushing restrains axial movement of the catch feature in the active catch state via contact between the catch feature and the catch bushing.

Abstract: Methods and kits are described for testing for the presence or absence of any fungus in a sample. Examples of fungi that can be detected include, but are not limited to, those belonging to the genera Candida, Aspergillus and Pneumocystis. The methods include obtaining a sample suspected of containing fungal nucleic acid, including at least one universal region of fungal nucleic acid, and testing for the presence or absence in the sample of the at least one universal region of fungal nucleic acid. Samples may be biological or non-biological.

Abstract: A detection panel for the universal detection of SARS-like coronaviruses and SARS-CoV-2 viruses and a method for using the detection panel are provided. The detection panel may be known as a Center for Discovery and Innovation (“CDI”) detection panel (CDI Enhanced COVID-19 Test) and may also include an additional primer/probe set in the detection panel to detect the human RNase P gene (RP) in control samples and clinical specimens. The detection panel is designed for both universal detection of SARS-like coronaviruses using an E gene (envelope) detection assay, and specific detection of the SARS-CoV-2, using an N2 (nucleocapsid) detection assay.

Abstract: A rotor catch system includes a catch stem having a proximal end coupled to a rotor of a mud motor system and a distal end positioned within a sub housing of a drill string, a catch feature having a top portion and a spindle portion extending from the top portion and coupled to the distal end of the catch stem, a housing catch feature extending radially inward from an inner surface of the sub housing, and a catch bushing positioned between the top portion of the catch feature and the housing catch feature. The housing catch feature restrains axial movement of the catch bushing in the active catch state via contact between the catch bushing and the housing catch feature, and the catch bushing restrains axial movement of the catch feature in the active catch state via contact between the catch feature and the catch bushing.

Abstract: A constant velocity joint for downhole power transmission has a first insert mounted in a radially extending drive shaft arm. The first insert engages a second insert mounted along a slot formed in a tubular housing disposed to receive the arm. The material for the two inserts may be different, having different galling properties. An insert may be shaped to have at least a flat surface, a cylindrical surface intersecting the flat surface, and a conical surface intersecting the cylindrical surface. The inserts may extend beyond the cavities in which they are mounted. Opposing cavity walls adjacent the cavity opening may be angled away from one another to permit the insert to flex under a load. The back wall of a cavity and back surface of an insert may be arcuate to permit rotational movement of the insert under a load.

Abstract: The handheld cleaning apparatus provides a handheld cleaning apparatus comprising a removable handle, abrasive particles, angled edges, open channels, and a flexible yet durable surface for scouring. The invention creates an abrasive, or “sanding,” cleaning apparatus that is better suited for cleaning dirty surfaces than a traditional cleaning sponge. The handheld cleaning apparatus retains the abrasive outer shell of a sanding sponge but is much more flexible and water permeable than current sanding sponges. To this end, the handheld cleaning apparatus comprises open channels, or “blow holes,” that promote water flow through the sponge and give the sponge flexibility. The size and the number of the channels vary by the material or density of the sponge. The handheld cleaning apparatus, additionally, contains a handle that is removably attached, which enables the consumer the ability to connect one or more cleaning apparatuses together to form the desired shape and form of the cleaning apparatus.

Abstract: Nucleic acid amplification assays for mutations to two short sections of the fungal gene FKS1. Mutations in these target sequences have been shown to correlate with resistance to echinocandin-class drugs. Assays may include detection by sequencing or by labeled hybridization probes. Also, primers, probes and reagent kits for performing such assays.

Abstract: A rotating cutter apparatus including a housing having a housing interior surface defining a housing bore, a shaft extending through the housing bore such that an annular space is provided between the housing interior surface and the shaft, and at least one cutter carried on the shaft. The shaft is rotatable relative to the housing about a shaft axis. The at least one cutter extends radially toward the housing interior surface and is rotatable relative to the housing about the shaft axis. A method for reducing a size of solid objects contained in a fluid, including providing a rotating cutter apparatus, introducing the fluid containing the solid objects into the rotating cutter apparatus, and rotating a shaft and at least one cutter in order to reduce the size of the solid objects while passing the fluid through the rotating cutter apparatus.

Abstract: An assembly for use in a wellbore can include a drill string having an outer housing and a thrust bearing sleeve positioned within the outer housing of the drill string. The assembly can also include a stationary thrust bearing positioned within the thrust bearing sleeve and coaxially around a mandrel extending through a longitudinal length of the thrust bearing sleeve. The assembly can further include an interlocking component including a first end coupled to the stationary thrust bearing and a second end positioned in a recessed portion of a housing of the drill string for preventing the stationary thrust bearing from rotating about a central axis of the mandrel, and for allowing the stationary thrust bearing to rotate about one or more axes perpendicular to the central axis. The assembly can include a flexible member for opposing a rotational force applied to the stationary thrust bearing by another thrust bearing.

Abstract: Methods and kits are described for testing for the presence or absence of any fungus in a sample. Examples of fungi that can be detected include, but are not limited to, those belonging to the genera Candida, Aspergillus and Pneumocystis. The methods include obtaining a sample suspected of containing fungal nucleic acid, including at least one universal region of fungal nucleic acid, and testing for the presence or absence in the sample of the at least one universal region of fungal nucleic acid. Samples may be biological or non-biological.

Abstract: The handheld cleaning apparatus provides a handheld cleaning apparatus comprising a removable handle, abrasive particles, angled edges, open channels, and a flexible yet durable surface for scouring. The invention creates an abrasive, or “sanding,” cleaning apparatus that is better suited for cleaning dirty surfaces than a traditional cleaning sponge. The handheld cleaning apparatus retains the abrasive outer shell of a sanding sponge but is much more flexible and water permeable than current sanding sponges. To this end, the handheld cleaning apparatus comprises open channels, or “blow holes,” that promote water flow through the sponge and give the sponge flexibility. The size and the number of the channels vary by the material or density of the sponge. The handheld cleaning apparatus, additionally, contains a handle that is removably attached, which enables the consumer the ability to connect one or more cleaning apparatuses together to form the desired shape and form of the cleaning apparatus.

Abstract: A drilling apparatus having a drive section and a bearing section axially distal to the drive section. The bearing section includes a unitary bearing housing defining a bearing housing bore, a driveshaft received within the bearing housing bore and rotatable relative to the bearing housing, and a bearing assembly radially interposed between the bearing housing and the driveshaft for rotatably supporting the driveshaft within the bearing housing bore. The unitary bearing housing may be connected directly with a transmission housing. An axis intersection point between a primary axis of the drilling apparatus and the driveshaft axis may be axially located between a proximal bearing housing end and a distal bearing housing end. One or more stationary bearing components may be non-rotatably engaged with one or more sleeves which are non-rotatably engaged with the bearing housing.

Abstract: The handheld cleaning apparatus provides a handheld cleaning apparatus comprising a removable handle, abrasive particles, angled edges, open channels, and a flexible yet durable surface for scouring. The invention creates an abrasive, or “sanding,” cleaning apparatus that is better suited for cleaning dirty surfaces than a traditional cleaning sponge. The handheld cleaning apparatus retains the abrasive outer shell of a sanding sponge but is much more flexible and water permeable than current sanding sponges. To this end, the handheld cleaning apparatus comprises open channels, or “blow holes,” that promote water flow through the sponge and give the sponge flexibility. The size and the number of the channels vary by the material or density of the sponge. The handheld cleaning apparatus, additionally, contains a handle that is removably attached, which enables the consumer the ability to connect one or more cleaning apparatuses together to form the desired shape and form of the cleaning apparatus.