Patents by Inventor Steven Patierno

Steven Patierno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Splice-switching oligonucleotides and methods of use
    Patent number: 11866689
    Abstract: The present disclosure provides methods and compositions for the treatment of cancer. In some aspects, the present disclosure provides splice-switching oligonucleotides that downregulate AR expression and methods of using these splice-switching oligonucleotides to treat cancer, specifically castrate resistant prostate cancer.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: January 9, 2024
    Assignee: Duke University
    Inventors: Jennifer Freedman, Steven Patierno, Daniel George, Bruce Sullenger, Bonnie LaCroix, Brendon Patierno
  • SPLICE-SWITCHING OLIGONUCLEOTIDES AND METHODS OF USE
    Publication number: 20210395754
    Abstract: The present disclosure provides methods and compositions for the treatment of cancer. In some aspects, the present disclosure provides splice-switching oligonucleotides that downregulate AR or EGFR expression and methods of using these splice-switching oligonucleotides to treat cancer.
    Type: Application
    Filed: September 1, 2021
    Publication date: December 23, 2021
    Inventors: Jennifer Freedman, Brendon Patierno, Bonnie LaCroix, Timothy Robinson, Bruce Sullenger, Daniel George, Steven Patierno
  • Splice-switching oligonucleotides and methods of use
    Patent number: 11136584
    Abstract: The present disclosure provides methods and compositions for the treatment of cancer. In some aspects, the present disclosure provides splice-switching oligonucleotides that downregulate AR or EGFR expression and methods of using these splice-switching oligonucleotides to treat cancer.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: October 5, 2021
    Assignee: Duke University
    Inventors: Jennifer Freedman, Brendon Patierno, Bonnie Lacroix, Timothy Robinson, Bruce Sullenger, Daniel George, Steven Patierno
  • Biomarkers for the Identification of Prostate Cancer and Methods of Use
    Publication number: 20210238696
    Abstract: The present disclosure provides biomarkers for the identification of prostate cancer and methods of use. The present disclosure also provide biomarkers that can be used for determining risk of developing prostate cancer, aggressiveness of prostate cancer and survival rate for subpopulations of African American males or non-Hispanic white males.
    Type: Application
    Filed: April 9, 2021
    Publication date: August 5, 2021
    Applicants: Duke University, George Washington University
    Inventors: Jennifer Freedman, Yanru Wang, Hongliang Liu, Qingyi Wei, Daniel George, Steven Patierno, Bi-Dar Wang, Norman Lee
  • Biomarkers for the identification of prostate cancer and methods of use
    Patent number: 10982285
    Abstract: The present disclosure provides biomarkers for the identification of prostate cancer and methods of use. The present disclosure also provide biomarkers that can be used for determining risk of developing prostate cancer, aggressiveness of prostate cancer and survival rate for subpopulations of African American males or non-Hispanic white males.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: April 20, 2021
    Assignees: DUKE UNIVERSITY, THE GEORGE WASHINGTON UNIVERSITY
    Inventors: Jennifer Freedman, Yanru Wang, Hongliang Liu, Qingyi Wei, Daniel George, Steven Patierno, Bi-Dar Wang, Norman Lee
  • SPLICE-SWITCHING OLIGONUCLEOTIDES AND METHODS OF USE
    Publication number: 20210024932
    Abstract: The present disclosure provides methods and compositions for the treatment of cancer. In some aspects, the present disclosure provides splice-switching oligonucleotides that downregulate AR expression and methods of using these splice-switching oligonucleotides to treat cancer, specifically castrate resistant prostate cancer.
    Type: Application
    Filed: March 22, 2019
    Publication date: January 28, 2021
    Applicant: Duke University
    Inventors: Jennifer Freedman, Steven Patierno, Daniel George, Bruce Sullenger, Bonnie Lacroix, Brendon Patierno
  • Splice-Switching Oligonucleotides and Methods of Use
    Publication number: 20180334677
    Abstract: The present disclosure provides methods and compositions for the treatment of cancer. In some aspects, the present disclosure provides splice-switching oligonucleotides that downregulate AR or EGFR expression and methods of using these splice-switching oligonucleotides to treat cancer.
    Type: Application
    Filed: November 4, 2016
    Publication date: November 22, 2018
    Inventors: Jennifer Freedman, Brendon Patierno, Bonnie Lacroix, Timothy Robinson, Bruce Sullenger, Daniel George, Steven Patierno
  • Biomarkers for the Identification of Prostate Cancer and Methods of Use
    Publication number: 20170166977
    Abstract: The present disclosure provides biomarkers for the identification of prostate cancer and methods of use. The present disclosure also provide biomarkers that can be used for determining risk of developing prostate cancer, aggressiveness of prostate cancer and survival rate for subpopulations of African American males or non-Hispanic white males.
    Type: Application
    Filed: November 4, 2016
    Publication date: June 15, 2017
    Inventors: Jennifer Freedman, Yanru Wang, Hongliang Liu, Qingyi Wei, Daniel George, Steven Patierno, Bi-Dar Wang, Norman Lee