Patents by Inventor Steven Peter BUTCHER

Steven Peter BUTCHER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bifunctional molecules for targeting Rpn11
    Patent number: 11925690
    Abstract: The invention provides for bifunctional molecules comprising an Rpn11 binding partner and a target protein binding partner. A bifunctional molecule according to the invention binds to Rpn11 and to the target protein, thereby facilitating degradation of the target protein bound to the target protein binding partner. The invention also provides for use of a bifunctional molecule for preventing or treating disease.
    Type: Grant
    Filed: June 13, 2019
    Date of Patent: March 12, 2024
    Assignee: AMPHISTA THERAPEUTICS LIMITED
    Inventors: Alessio Ciulli, Andrea Testa, Scott Hughes, Steven Peter Butcher
  • BIFUNCTIONAL MOLECULES FOR TARGETING UCHL5
    Publication number: 20210283139
    Abstract: The invention provides for bifunctional molecules comprising an UchL5 binding partner and a target protein binding partner linked via a flexible linker. A bifunctional molecule according to the invention binds to UchL5 and to the target protein, thereby facilitating degradation of the target protein bound to the target protein binding partner. The invention also provides for use of a bifunctional molecule for preventing or treating disease.
    Type: Application
    Filed: June 13, 2019
    Publication date: September 16, 2021
    Inventors: Alessio CIULLI, Andrea TESTA, Scott HUGHES, Steven Peter BUTCHER
  • BIFUNCTIONAL MOLECULES FOR TARGETING RPN11
    Publication number: 20210260200
    Abstract: The invention provides for bifunctional molecules comprising an Rpn11 binding partner and a target protein binding partner. A bifunctional molecule according to the invention binds to Rpn11 and to the target protein, thereby facilitating degradation of the target protein bound to the target protein binding partner. The invention also provides for use of a bifunctional molecule for preventing or treating disease.
    Type: Application
    Filed: June 13, 2019
    Publication date: August 26, 2021
    Inventors: Alessio CIULLI, Andrea TESTA, Scott HUGHES, Steven Peter BUTCHER