Patents by Inventor Steven Podos

Steven Podos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF COMPLEMENT FACTOR D INHIBITORS ALONE OR IN COMBINATION WITH ANTI-C5 ANTIBODIES FOR TREATMENT OF PAROXYSMAL NOCTURNAL HEMOGLOBINURIA
    Publication number: 20230172930
    Abstract: Provided are methods for treating paroxysmal nocturnal hemoglobinuria in a subject who previously exhibited an inadequate response to an anti-C5 antibody therapy, by administering to the subject a therapeutically effective amount of an inhibitor of the alternative pathway of complement (e.g., one which inhibits a target upstream to complement 5 (C5), such as Factor D or complement 3 (C3)). Also provided herein are methods for treating PNH in a human subject, comprising administering to the subject a complement factor D inhibitor alone or in combination with an anti-C5 antibody, or antigen binding fragment thereof. In some embodiments, the patient previously exhibited an inadequate response to an anti-C5 antibody therapy.
    Type: Application
    Filed: May 11, 2021
    Publication date: June 8, 2023
    Applicant: Alexion Pharmaceuticals, Inc.
    Inventors: Mingjun Huang, James Hui, Steven Podos, Dharaben Patel, Michael Geffner
  • Method of reducing intraocular pressure and treating glaucoma using corynanthine
    Patent number: 4490379
    Abstract: This invention relates to a method of reducing intraocular pressure and treating glaucoma in mammals which comprises administering topically to the eye a pharmaceutically acceptable salt isomeric to yohimbine and stereochemically similar to corynanthine in an amount effective to reduce intraocular pressure.
    Type: Grant
    Filed: April 4, 1984
    Date of Patent: December 25, 1984
    Inventors: Steven Podos, Janet B. Serle, Thomas Mittag
  • Method of reducing intraocular pressure with salts of vanadic acid
    Patent number: 4343794
    Abstract: This invention relates to a method of reducing intraocular pressure in mammals which comprises administering topically to the eye a vanadium compound in an amount effective to reduce intraocular pressure.
    Type: Grant
    Filed: May 6, 1980
    Date of Patent: August 10, 1982
    Assignees: Mt. Sinai, Washington University
    Inventors: Steven Podos, Theodore Krupin, Bernard Becker