Abstract: Secure operations can be performed using security module instances offered as a web service through a resource provider environment. State data and cryptographic material can be loaded and unloaded from the instance as needed, such that the instance can be reused for operations of different customers. The material and data can be stored as a bundle encrypted using a key specific to the hardware security module and a key specific to the resource provider, such that the bundle can only be decrypted in an instance of that type of security module from the associated manufacturer and operated by that particular resource provider. The customer is then only responsible for the allocation of that instance during the respective cryptographic operation(s).

Abstract: A virtual cryptographic module is used to perform cryptographic operations. The virtual cryptographic module may include a fleet of cryptographic modules and a load balancer that determines when a cryptographic module should be added to or removed from the fleet. The fleet size may be adjusted based on detecting a set of conditions that includes the utilization level of the fleet. One or more cryptographic modules of the fleet may be used to fulfill requests to perform cryptographic operations. A cryptographic module may be a hardware security module (“HSM”).

Abstract: The present disclosure relates to an inhibitor of human TRPM3 for use in the treatment or prevention of migraine, including in subjects whose migraines are not responsive to CGRP inhibition or whose migraines are responsive to triptans. Combination therapies are also described. In other aspects, the present disclosure provides methods for identifying suitable patients, methods for identifying inhibitors of human TRPM3, cell lines and agonists for use in such methods and a method for measuring PACAP release.

Abstract: Drainage channels are added to a control joint to provide a weeping control joint wherein condensate or other sources of water that finds its way between the stucco and the substrate, above the weeping control joint, flows through the channels to the exterior surface of the stucco below the weeping control joint.

Abstract: A virtual hardware security module (“HSM”) is used to perform cryptographic operations. The virtual HSM may provision and coordinate requests between one or more HSMs within a fleet of HSMs. A set of cryptographic keys and/or digital certificates may be exchanged between a client and the virtual HSM such that the client and the virtual HSM may communicate with each other via a cryptographically protected communication session. The fleet of HSMs of a virtual HSM may be scaled up or scaled down according to various criteria. Cryptographic key material may be propagated between HSMs of the fleet using a fleet transfer key. Digital certificates may be used to demonstrate that one or more cryptographic keys were generated by a service provider and/or manufacturer.

Abstract: Secure operations can be performed using security module instances offered as a web service through a resource provider environment. State data and cryptographic material can be loaded and unloaded from the instance as needed, such that the instance can be reused for operations of different customers. The material and data can be stored as a bundle encrypted using a key specific to the hardware security module and a key specific to the resource provider, such that the bundle can only be decrypted in an instance of that type of security module from the associated manufacturer and operated by that particular resource provider. The customer is then only responsible for the allocation of that instance during the respective cryptographic operation(s).

Abstract: A virtual cryptographic module is used to perform cryptographic operations. The virtual cryptographic module may include a fleet of cryptographic modules and a load balancer that determines when a cryptographic module should be added to or removed from the fleet. The fleet size may be adjusted based on detecting a set of conditions that includes the utilization level of the fleet. One or more cryptographic modules of the fleet may be used to fulfill requests to perform cryptographic operations. A cryptographic module may be a hardware security module (“HSM”).

Abstract: Secure operations can be performed using security module instances offered as a web service through a resource provider environment. State data and cryptographic material can be loaded and unloaded from the instance as needed, such that the instance can be reused for operations of different customers. The material and data can be stored as a bundle encrypted using a key specific to the hardware security module and a key specific to the resource provider, such that the bundle can only be decrypted in an instance of that type of security module from the associated manufacturer and operated by that particular resource provider. The customer is then only responsible for the allocation of that instance during the respective cryptographic operation(s).

Abstract: Drainage channels are added to a control joint to provide a weeping control joint wherein condensate or other sources of water that finds its way between the stucco and the substrate, above the weeping control joint, flows through the channels to the exterior surface of the stucco below the weeping control joint.

Abstract: A vertical exterior wall system has an exterior substrate and a control joint disposed on the substrate. A building material such as stucco covers a base plate of the control joint. An A-shaped ridge extends from the based plate of the control joint and is disposed between a first area of the building material and a second area of the building material, defining a gap. A sealant may be disposed in the gap and may cover the A-shaped ridge, adhering to building materials of the first area and the second area.

Abstract: A virtual hardware security module (“HSM”) is used to perform cryptographic operations. The virtual HSM may provision and coordinate requests between one or more HSMs within a fleet of HSMs. A set of cryptographic keys and/or digital certificates may be exchanged between a client and the virtual HSM such that the client and the virtual HSM may communicate with each other via a cryptographically protected communication session. The fleet of HSMs of a virtual HSM may be scaled up or scaled down according to various criteria. Cryptographic key material may be propagated between HSMs of the fleet using a fleet transfer key. Digital certificates may be used to demonstrate that one or more cryptographic keys were generated by a service provider and/or manufacturer.

Abstract: A virtual cryptographic module is used to perform cryptographic operations. The virtual cryptographic module may include a fleet of cryptographic modules and a load balancer that determines when a cryptographic module should be added to or removed from the fleet. The fleet size may be adjusted based on detecting a set of conditions that includes the utilization level of the fleet. One or more cryptographic modules of the fleet may be used to fulfill requests to perform cryptographic operations. A cryptographic module may be a hardware security module (“HSM”).

Abstract: A virtual hardware security module (“HSM”) is used to perform cryptographic operations. The virtual HSM may provision and coordinate requests between one or more HSMs within a fleet of HSMs. A set of cryptographic keys and/or digital certificates may be exchanged between a client and the virtual HSM such that the client and the virtual HSM may communicate with each other via a cryptographically protected communication session. The fleet of HSMs of a virtual HSM may be scaled up or scaled down according to various criteria. Cryptographic key material may be propagated between HSMs of the fleet using a fleet transfer key. Digital certificates may be used to demonstrate that one or more cryptographic keys were generated by a service provider and/or manufacturer.

Abstract: A virtual cryptographic module is used to perform cryptographic operations. The virtual cryptographic module may include a fleet of cryptographic modules and a load balancer that determines when a cryptographic module should be added to or removed from the fleet. The fleet size may be adjusted based on detecting a set of conditions that includes the utilization level of the fleet. One or more cryptographic modules of the fleet may be used to fulfill requests to perform cryptographic operations. A cryptographic module may be a hardware security module (“HSM”).

Abstract: A vertical exterior wall system has an exterior substrate and a control joint disposed on the substrate. A building material such as stucco covers a base plate of the control joint. An A-shaped ridge extends from the based plate of the control joint and is disposed between a first area of the building material and a second area of the building material, defining a gap. A sealant may be disposed in the gap and may cover the A-shaped ridge, adhering to building materials of the first area and the second area.

Abstract: Secure operations can be performed using security module instances offered as a web service through a resource provider environment. State data and cryptographic material can be loaded and unloaded from the instance as needed, such that the instance can be reused for operations of different customers. The material and data can be stored as a bundle encrypted using a key specific to the hardware security module and a key specific to the resource provider, such that the bundle can only be decrypted in an instance of that type of security module from the associated manufacturer and operated by that particular resource provider. The customer is then only responsible for the allocation of that instance during the respective cryptographic operation(s).

Abstract: A building comprises an exterior substrate, such as an exterior prepped for application of a building material and one or more expansion and control joints. A terminating point, such as a window or door casing, has a surface extending above the substrate, and a casing bead control joint with a permanent gasket or backer rod preinstalled for filling the space between the casing and the control joint. The control joint may be combined with one or more other expansion or control joints fixed to the exterior of the substrate, and a layer of a building material may be applied on the substrate and overlapping a portion of the expansion and control joints.

Abstract: Systems, devices and processes are described for implementing an access heartbeat role on a hardware security module (HSM) that stores secure data on behalf of a secure data owner. Heartbeat and access credentials are established and distributed by the HSM. Access to the secure data is prevented unless the HSM receives valid heartbeats prior to a time expiration along with a valid access request. Generally, heartbeats are signed messages and include heartbeat credentials. Access requests may also be signed messages and include access credentials. The access credentials may be suspended, revoked or the entire HSM may be zeroized (e.g., plaintext keys erased), dependent upon a failure to receive valid heartbeats in a timely fashion. Heartbeats may be required from multiple entities, in some embodiments. Some example configurable features include heartbeat expiration time, the source of the credentials, the access denial options, and how many sources of distinct heartbeats are required.

Abstract: Secure operations can be performed using security module instances offered as a web service through a resource provider environment. State data and cryptographic material can be loaded and unloaded from the instance as needed, such that the instance can be reused for operations of different customers. The material and data can be stored as a bundle encrypted using a key specific to the hardware security module and a key specific to the resource provider, such that the bundle can only be decrypted in an instance of that type of security module from the associated manufacturer and operated by that particular resource provider. The customer is then only responsible for the allocation of that instance during the respective cryptographic operation(s).

Abstract: A building comprises an exterior substrate, such as an exterior prepped for application of a building material and one or more expansion and control joints. A window or door casing has a surface extending above the substrate, and a casing bead control joint with a spacer strip defining a space between the casing and the control joint. For example, the strip is removable by peeling away the strip from an adjacent flange, which may have an optional permanent gasket or back rod preinstalled for filling the space between the casing and the control joint. The control joint may be combined with one or more other expansion or control joints fixed to the exterior of the substrate and a layer of a building material may be applied on the substrate and overlapping a portion of the expansion and control joints.