Abstract: A method of tubal recanalization comprising advancing an everting catheter adapted for dilatation and an endoscope to a position adjacent the site of a stenosis in an internal tubal passage of a patient. The everting catheter includes an endoscope lumen and the endoscope is within the endoscope lumen. The everting element is everted to a location within the stenosis and is then expanded to reduce the stenosis. When the tubal passage has been opened sufficiently, the everting element is retracted. The site of the stenosis is viewed using the endoscope and such viewing may be carried out prior to expansion of the everting element to locate the site as well as after the everting element has been retracted.

Abstract: A method of positioning an elongated instrument in an everting catheter is disclosed. The everting catheter includes an inflatable everting element which circumscribes a region of the instrument and which is inflated to grip the instrument. The everting catheter and instrument extend into a patient to a desired region within the body. Flush solution is introduced between the everting element and the instrument, and the instrument is moved relative to the everting element while the flush solution is between the everting element and the instrument.

Abstract: An endoscope comprising an elongated endoscope body having a proximal end and a distal end. The endoscope body is sized and adapted for insertion into an interior body region of a patient. Optical components are carried by the endoscope body to enable viewing of the interior body region of the patient. The endoscope body has an outer surface which defines a groove having a portion which extends distally of the endoscope body.

Abstract: A method of making an intraocular lens including providing a fixation member having a proximal end portion with the proximal end portion including an elongated filament, converting a region of said filament at said proximal end portion from a first configuration into an enlargement having a rounded surface and attaching an optic about the proximal end portion of the fixation member to attach the fixation member to the optic.

Abstract: A catheter comprising an elongated catheter body having a lumen with a distal opening, an elongated inner tube having a flexible distal end portion and a flexible everting element coupled to the catheter body and the inner tube so that the everting element can be inverted and everted to the distal opening. The inner tube has an inner tube lumen which extends through the distal end portion of the inner tube. The distal end portion of the inner tube includes a flexible tubular layer and a flexible reinforcing layer which reinforces the tubular layer and inhibits radial collapse of the inner tube lumen in the distal end portion of the inner tube.

Abstract: An everting balloon catheter having a distal end opening defined by a beveled rim is disclosed. The distal end portion of a catheter, e.g., an everting balloon catheter, can be made radioopaque by bonding a distal end portion comprising a polymeric material doped with a major amount of radioopaque metals onto a catheter body. Alternately, a composition comprising polymeric adhesives, and/or precursors of polymeric adhesives, and a major amount of radioopaque metal components can be placed, e.g., painted on the distal end portion of a catheter body to provide the desired degree of radioopacity.

Abstract: A method of making an intraocular lens including providing a fixation member having a proximal end portion with the proximal end portion including an elongated filament, converting a region of said filament at said proximal end portion from a first configuration into a second configuration which is adapted to provide a mechanical interlock and molding an optic about the proximal end portion of the fixation member to form a mechanical interlock between the second configuration and the optic and to attach the fixation member to the optic.

Abstract: A method of making an intraocular lens including providing a fixation member having a proximal end portion with the proximal end portion including an elongated filament, converting a region of said filament at said proximal end portion from a first configuration into a second configuration which is adapted to provide a mechanical interlock and molding an optic about the proximal end portion of the fixation member to form a mechanical interlock between the second configuration and the optic and to attach the fixation member to the optic.

Abstract: A method of making an intraocular lens including providing a fixation member having a proximal end portion with the proximal end portion including an elongated filament, converting a region of said filament at said proximal end portion from a first configuration into a second configuration which is adapted to provide a mechanical interlock and molding an optic about the proximal end portion of the fixation member to form a mechanical interlock between the second configuration and the optic and to attach the fixation member to the optic.