Patents by Inventor Steven R. Duncan

Steven R. Duncan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150191786
    Abstract: The present invention relates to methods and compositions that may be used to predict the risk of an individual, for example a smoker, for developing chronic obstructive pulmonary disease (“COPD”), emphysema or idiopathic pulmonary fibrosis (“IPF”).
    Type: Application
    Filed: August 19, 2014
    Publication date: July 9, 2015
    Applicant: University of Pittsburgh - of the Commonwealth System of Higher Education
    Inventors: Marjorie P. George, Steven R. Duncan
  • Publication number: 20150064724
    Abstract: The present invention relates to biomarkers that may be used to evaluate the prognoses of patients suffering from pulmonary diseases and assist in the determination of appropriate therapeutic regimens. It is based, at least in part, on the discovery that a number of T-cell antigens are differentially expressed in chronic lung disease patients depending on the prognosis of the patient. Non-limiting examples of these antigens include CD28, CD4, CD25, CD45, CD27 and CCR7 and combinations thereof. Use of these biomarker antigens, optionally in conjunction with pulmonary function tests, provides an indication of which patients are likely to suffer a severely adverse outcome within the year and/or be refractory to treatment.
    Type: Application
    Filed: October 30, 2014
    Publication date: March 5, 2015
    Applicant: University of Pittsburgh - of the Commonwealth System of Higher Education
    Inventor: Steven R. Duncan
  • Publication number: 20120237954
    Abstract: The present invention relates to biomarkers that may be used to evaluate the prognoses of patients suffering from pulmonary diseases and assist in the determination of appropriate therapeutic regimens. It is based, at least in part, on the discovery that a number of T-cell antigens are differentially expressed in chronic lung disease patients depending on the prognosis of the patient. Non-limiting examples of these antigens include CD28, CD4, CD25, CD45, CD27 and CCR7 and combinations thereof. Use of these biomarker antigens, optionally in conjunction with pulmonary function tests, provides an indication of which patients are likely to suffer a severely adverse outcome within the year and/or be refractory to treatment.
    Type: Application
    Filed: March 28, 2012
    Publication date: September 20, 2012
    Applicant: University of Pittsburgh - of the Commonwealth System of Higher Education
    Inventor: Steven R. Duncan
  • Publication number: 20120172240
    Abstract: The present invention relates to methods and compositions that may be used to predict the risk of an individual, for example a smoker, for developing chronic obstructive pulmonary disease (“COPD”), emphysema or idiopathic pulmonary fibrosis (“IPF”).
    Type: Application
    Filed: December 21, 2011
    Publication date: July 5, 2012
    Inventors: Jianmin Xue, Marjorie P. George, Steven R. Duncan
  • Publication number: 20110111437
    Abstract: The present invention relates to biomarkers that may be used to evaluate the prognoses of patients suffering from pulmonary diseases and assist in the determination of appropriate therapeutic regimens. It is based, at least in part, on the discovery that a number of T-cell antigens are differentially expressed in chronic lung disease patients depending on the prognosis of the patient. Non-limiting examples of these antigens include CD28, CD4, CD25, CD45, CD27 and CCR7 and combinations thereof. Use of these biomarker antigens, optionally in conjunction with pulmonary function tests, provides an indication of which patients are likely to suffer a severely adverse outcome within the year and/or be refractory to treatment.
    Type: Application
    Filed: October 8, 2010
    Publication date: May 12, 2011
    Applicant: THE UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventor: Steven R. Duncan