Patents by Inventor Steven R. Shuken

Steven R. Shuken has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ladderane lipid compounds and liposomes and methods of preparing and using the same
    Patent number: 10745424
    Abstract: Methods for preparing a variety of ladderane precursors, ladderane compounds and ladderane lipids are provided. Also provided are methods of preparing a liposome from the ladderane lipids disclosed herein, and compositions thereof. Aspects of the invention include encapsulated one or more cargo moieties in the liposome or compositions thereof and use of the subject liposome compositions as vehicles in drug delivery, imaging, diagnostics and other medical applications. Aspects of the methods disclosed herein include administering a liposomal composition comprising a pharmaceutical agent to a subject under conditions sufficient to deliver the composition to a site of interest in the subject, and release the pharmaceutical agent from the liposomal composition.
    Type: Grant
    Filed: August 30, 2017
    Date of Patent: August 18, 2020
    Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Noah Burns, Steven R. Shuken, Jaron A. M. Mercer, Carolyn M. Cohen
  • Fluorogenic water soluble hydrazine sensors
    Patent number: 10732108
    Abstract: Water soluble fluorogenic sensors for detecting a hydrazine analyte are provided. Aspects of the fluorogenic sensors include at least one water soluble group and a hydrazine reactive group. Methods of evaluating a sample for the presence of a hydrazine analyte and methods of detecting hydrazine diffusion across a phospholipid membrane are provided. Kits for practicing the subject methods are also provided.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: August 4, 2020
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Noah Burns, Steven R. Shuken
  • Ladderane Lipid Compounds and Liposomes and Methods of Preparing and Using the Same
    Publication number: 20190177347
    Abstract: Methods for preparing a variety of ladderane precursors, ladderane compounds and ladderane lipids are provided. Also provided are methods of preparing a liposome from the ladderane lipids disclosed herein, and compositions thereof. Aspects of the invention include encapsulated one or more cargo moieties in the liposome or compositions thereof and use of the subject liposome compositions as vehicles in drug delivery, imaging, diagnostics and other medical applications. Aspects of the methods disclosed herein include administering a liposomal composition comprising a pharmaceutical agent to a subject under conditions sufficient to deliver the composition to a site of interest in the subject, and release the pharmaceutical agent from the liposomal composition.
    Type: Application
    Filed: August 30, 2017
    Publication date: June 13, 2019
    Inventors: Noah Burns, Steven R. Shuken, Jaron A.M. Mercer, Carolyn M. Cohen
  • FLUOROGENIC WATER SOLUBLE HYDRAZINE SENSORS
    Publication number: 20190033215
    Abstract: Water soluble fluorogenic sensors for detecting a hydrazine analyte are provided. Aspects of the fluorogenic sensors include at least one water soluble group and a hydrazine reactive group. Methods of evaluating a sample for the presence of a hydrazine analyte and methods of detecting hydrazine diffusion across a phospholipid membrane are provided. Kits for practicing the subject methods are also provided.
    Type: Application
    Filed: July 26, 2018
    Publication date: January 31, 2019
    Inventors: Noah Burns, Steven R. Shuken