Abstract: A chemical genus of sulfated cholestanes attached to an oligomer through amide or ester bonds is disclosed. The compounds are useful as anti human immunodeficiency virus (HIV) and anti-herpes simplex virus (HSV) agents. The compounds have the general formula in which CPS (the structure within the square brackets) is a cholanic acid derivative. R1 to R16 are chosen independently from H, OH and OSO3?A+. W is a direct bond or a deshydrogen residue of a C3-C6 diol or triol. A is chosen from H+, a quaternary ammonium species and the cation of an alkali or alkaline earth metal. Z is a direct bond or a residue of an amino acid, a peptide or an aminosulfonic acid. ? is a moiety having n or more —NH and —OH groups separated by 6 or fewer carbons; and n is an integer from 6 to 200.

Abstract: The present invention relates to a Langmuir-Blodgett (LB) thin film, which includes: at least one molecular layer, which includes one or more monolayer-forming surfactant molecules having a first ionic charge, ionically cross-linked with at least one water-soluble agent having a second ionic charge; wherein a total amount of the first and second charges is at least 5; and wherein each of the first and second charges is independently 2 or greater. The present invention also relates to novel polymerizable surfactant compounds as well as articles and methods using the thin film, and methods of making the thin film.