Abstract: The invention relates to (among other things) a method of administering to a patient suffering from a cancer, the method comprising the steps of: (a) administering an IL-2R?-activating amount of a long acting, IL-2R?-selective agonist; and (b) administering a CTLA-4 pathway-inhibiting amount of an anti-CTLA-4 antibody or a PD-1 pathway-inhibiting amount of an anti-PD-1 antibody.

Abstract: An airfoil for a turbine engine can include an outer wall bounding an interior and defining a pressure side and a suction side extending between a leading edge and a trailing edge to define a chord-wise direction and extending between a root and a tip to define a span-wise direction. A plurality of outlets and a plurality of scalloped portions can extend proximate the trailing edge.

Abstract: An airfoil for a turbine engine, comprising an outer wall defining an exterior surface bounding an interior and defining a pressure side and a suction side extending between a leading edge and a trailing edge to define a chord-wise direction and extending between a root and a tip to define a span-wise direction, outlets on the exterior surface, and a cooling air supply conduit within the interior and having a supply passage.

Abstract: An airfoil for a turbine engine can include an outer wall bounding an interior and defining a pressure side and a suction side extending between a leading edge and a trailing edge to define a chord-wise direction and extending between a root and a tip to define a span-wise direction. A plurality of outlets and a plurality of scalloped portions can extend proximate the trailing edge.

Abstract: A system includes at least one unmanned aerial vehicle and at least one unmanned vehicle communicatively coupled to the unmanned aerial vehicle. The unmanned aerial vehicle includes a propulsion system and an onboard pilot system configured to determine a flight path for the unmanned aerial vehicle. The unmanned vehicle includes a propulsion system and a localization system configured to determine a location of the unmanned aerial vehicle relative to the unmanned vehicle. The unmanned vehicle further includes a communication component configured to transmit location information to the unmanned aerial vehicle. The onboard pilot system is configured to determine the flight path based on the location information provided by the unmanned vehicle.

Abstract: The present approach employs a context-aware simulation platform to facilitate control of a robot remote from an operator. Such a platform may use the prior domain/task knowledge along with the sensory feedback from the remote robot to infer context and may use inferred context to dynamically change one or both of simulation parameters and a robot-environment-task state being simulated. In some implementations, the simulator instances make forward predictions of their state based on task and robot constraints. In accordance with this approach, an operator may therefore issue a general command or instruction to a robot and based on this generalized guidance, the actions taken by the robot may be simulated, and the corresponding results visually presented to the operator prior to evaluate prior to the action being taken.

Abstract: A telepresence apparatus includes a first computer assembly configured to interface with a first memory assembly configured to tangibly store programmed coded instructions. The programmed coded instructions are configured to urge the first computer assembly to compute whether to suspend transmission of an aspect of a telepresence data unit to the second computer assembly via the communication network depending on a match made between a user gesture signal and a predetermined user gesture.

Abstract: The invention relates to (among other things) a method of administering to a patient suffering from a cancer, the method comprising the steps of: (a) administering an IL-2R?-activating amount of a long acting, IL-2R?-selective agonist; and (b) administering a CTLA-4 pathway-inhibiting amount of an anti-CTLA-4 antibody or a PD-1 pathway-inhibiting amount of an anti-PD-1 antibody.

Abstract: The present disclosure provides methods, compositions, and kits for methods that can improve techniques nucleic acid analysis, and can allow for more reliable and accurate targeted, multiplexed, high throughput sequencing. The methods, compositions, and kits can be used for sequencing target loci of nucleic acid. The methods, compositions, and kits disclosed herein can be used for assisted de novo targeted sequencing. The methods, compositions, and kits disclosed herein can also be used for library labeling for de novo sequencing and phasing.

Abstract: Described herein, an anhydrous cosmetic composition includes one or more water-absorbing components; a malodour-controlling component; a cosmetically acceptable carrier; wherein the anhydrous cosmetic composition has a burst resistance pressure greater than about 137.9 mBar (2 psi); wherein the anhydrous cosmetic composition has a water vapor sorption per 100 g of the composition from about 2.0 g to about 15 g; and wherein the anhydrous cosmetic composition is essentially free of aluminium-based antiperspirant actives.

Abstract: Described herein, an anhydrous cosmetic composition includes a first water-absorbing component having a water vapor sorption greater than about 20 g per 100 g of the first water-absorbing component according to the Water Vapor Sorption Test Method as disclosed herein; a second water-absorbing component having a water vapor sorption from about 8.5 to about 19.9 g per 100 g of the second water-absorbing component according to the Water Vapor Sorption Test Method as disclosed herein; a malodour-controlling component; a cosmetically acceptable carrier; and wherein the anhydrous cosmetic composition is essentially free of aluminum-based antiperspirant actives.

Abstract: Described herein, an anhydrous cosmetic composition includes a first water-absorbing component comprising a mixture of a superabsorbent polymer and a polyquaternium; a second water-absorbing component selected from the group consisting of starch particles, a stearate component, and mixtures thereof; a malodour-controlling component; a cosmetically acceptable carrier; and wherein the anhydrous cosmetic composition is essentially free of aluminum-based antiperspirant actives.

Abstract: The present disclosure relates to reinforcement devices, systems and methods for use in constructing new structures, including post frame structures. Specifically, the present disclosure relates to reinforcement devices, systems and methods for replacing traditional wood and/or precast concrete columns utilized in building a new construction foundation, with a height adjustable foundation column assembly constructed from a corrosion resistant material. The present disclosure also relates to reinforcement devices, systems and methods useful for reinforcing existing post frame structures, particularly those with framing elements requiring repair.

Abstract: A method of distributing data in a distributed storage system includes receiving a file, dividing the received file into chunks, and determining a distribution of the chunks among storage devices of the distributed storage system based on a maintenance hierarchy of the distributed storage system. The maintenance hierarchy includes maintenance levels, and each maintenance level includes one or more maintenance units. Each maintenance unit has an active state and an inactive state. Moreover, each storage device is associated with a maintenance unit. The determining of the distribution of the chunks includes identifying a random selection of the storage devices matching a number of chunks of the file and being capable of maintaining accessibility of the file when one or more maintenance units are in an inactive state. The method also includes distributing the chunks to storage devices of the distributed storage system according to the determined distribution.

Abstract: A component, such as for a turbine engine, can include an airfoil with an outer wall defining an exterior surface bounding an interior and defining a pressure side and a suction side extending between a leading edge and a trailing edge to define a chord-wise direction and extending between a root and a tip to define a span-wise direction. The component can also include at least one cooling passage within the interior.

Abstract: A passive fire suppression system including at least one tapered cellular glass block and having a cap with a tapered shape disposed on the top of the at least one cellular glass block. The passive fire suppression system allows drainage from the upper surface to the bottom of the system. The drainage is beneficial for both environmental conditions such as rain as well as for incidents where combustible liquids are spilled on the top surface of the system. Therefore, the system will not only shield any combustible materials that are under the system but will also quickly drain any combustible liquids that may spill onto the top of the system to the lower surface.

Abstract: A cable pull switch includes a polychotomous sensor configured to provide a reading of at least one of a plurality of values, the reading corresponding to a tension on a pull cable or a linear displacement of an end of a pull cable. A processor coupled to the polychotomous cable pull sensor configured to determine a rate of change of the value of the reading from the sensor and determine an occurrence of a cable pull event, the determination based on the determined rate of change of the value, and determine whether the rate of change of the value of an electrical resistance through the polychotomous cable pull sensor is below a threshold rate of change value, and adjust an upper pull threshold value to a new upper pull threshold value that is based on a present reading of the value of the electrical resistance through the strain gauge.

Abstract: Systems, methods and computer readable memory devices for delivering a presentation are provided. In one example, a method includes establishing a wireless network access point that creates a closed wireless network. An encrypted communication session is established via the closed wireless network with a plurality of client computing devices. A virtual network server is run on the host computing device, and each of the client computing devices is communicatively coupled to the virtual network server. A subset of the plurality of client computing devices is selected, and audio/video data is streamed to only the subset of the client computing devices.

Abstract: Technology is disclosed for managing network storage services by service level objectives (SLOs). The method receives multiple service level capability (SLC) templates; creates at least one storage service level (SSL) instance using at least one of the SLC templates; provisions a storage object located in a network storage infrastructure based on the SSL instance; and services storage requests using the storage object.

Abstract: The present invention provides a new and distinct cannabis cultivar designated as ‘BIHEMP 050924.’ Disclosed herein are main terpenes of ‘BIHEMP 050924,’ which are beta-caryophyllene, limonene, alpha-humulene, linalool, myrcene, trans-ocimene, beta-pinene, fenchol, and alpha-terpineol. Also, the present invention provides the estimated concentration of the THCmax, CBDmax, and CBGmax, about 0.21-0.43%, about 5.02-10.86%, and about 0.10-0.72%, respectively, at the time of assaying metabolites from flower samples of ‘BIHEMP 050924.