Abstract: An apparatus to produce an OCT of an eye or a brain of a patient to identify one or more plaques in a plurality of discrete OCT retinal layers. The apparatus also includes a plurality of methods for identifying one or more plaques in a plurality of discrete OCT retinal layers that can include a contrast agent and a normative database.

Abstract: An eye imaging apparatus to produce an image of an eye of a patient user is disclosed. The eye imaging apparatus may include a video camera, a slit lamp chinrest, a camera housing, a plurality of illumination source optics and a processing system. The eye imaging apparatus may also include a video camera, a plurality of video camera optics, a camera housing, a microscope assembly, a plurality of illumination source optics and a floor base. The eye imaging apparatus may be utilized in combination with one or more contrasting agents. The eye imaging apparatus may detect amyloid-beta plaque, amyloid or amyloid-beta peptide by a spectral signature.

Abstract: The present invention is an apparatus and method to produce an image of an eye of a patient that includes an optical head that includes imaging optics, illumination source optics and a camera housing with a perimeter that houses the video camera optics and the illumination source optics, a slit lamp chinrest and joystick assembly that includes an adjustable head support, a movable base, a joystick that adjusts a position of the camera housing relative to the head support and the housing support that mounts the video camera, a rubber eyecup that provides an interface between the camera housing and the patient's eye that protrudes outward from the perimeter and a computer system that analyzes images and data for the presence of amyloid in a retina, and other deposits and provides a diagnosis of macular degeneration, Alzheimer's disease, traumatic brain injury, multiple concussive injury, neurodegenerative and other ocular disorders.

Abstract: A slit lamp mounted eye imaging, a slit lamp integrated, a handheld, OCT integrated, or attached to a separate chinrest-joystick assembly apparatus and method for producing a wide field and/or magnified views of the posterior or the anterior segments of an eye through an undilated or dilated pupil is disclosed. The apparatus images sections and focal planes and utilizes an illumination system that uses one or more LEDs, shifting optical elements, flipping masks, and/or aperture stops where the light can be delivered into the optical system on optical axis or off axis from center of optical system and return imaging path from the eye, creating artifacts in different locations on the eye image. Image processing is employed to detect and eliminate artifacts and masks from images. The apparatus can be used in combination with an OCT, microscope and can be disposed in a hand-held housing for hand-held use.

Abstract: A slit lamp mounted eye imaging a slit lamp integrated, a handheld, OCT integrated, or attached to a separate chinrest-joystick assembly apparatus for producing a wide field and/or magnified views of the posterior or the anterior segments of an eye through an undilated or dilated pupil. The apparatus images sections and focal planes and utilizes an illumination system that uses one or more LEDs, shifting optical elements, flipping masks, and/or aperture stops where the light can be delivered into the optical system on optical axis or off axis from center of optical system and return imaging path from the eye, creating artifacts in different locations on the eye image. Image processing is employed to detect and eliminate artifacts and masks from images. The apparatus can be used in combination with an OCT, microscope and can be disposed in a hand-held housing for hand-held use.

Abstract: A slit lamp mounted eye imaging a slit lamp integrated, a handheld, OCT integrated, or attached to a separate chinrest-joystick assembly apparatus for producing a wide field and/or magnified views of the posterior or the anterior segments of an eye through an undilated or dilated pupil. The apparatus images sections and focal planes and utilizes an illumination system that uses one or more LEDs, shifting optical elements, flipping masks, and/or aperture stops where the light can be delivered into the optical system on optical axis or off axis from center of optical system and return imaging path from the eye, creating artifacts in different locations on the eye image. Image processing is employed to detect and eliminate artifacts and masks from images. The apparatus can be used in combination with an OCT, microscope and can be disposed in a hand-held housing for hand-held use.

Abstract: A system and method for imaging a patient user's body part is disclosed. The system may include a patient user body part imaging non-transitory storage media to image a patient user body part. The method may include selecting an optical imaging device to image the patient user's body part, acquiring one or more data sets with the optical imaging device, the acquiring is performed with focus at multiple axial positions and exposure control or deliberate focus at specified image locations and exposure control, registering the acquired data sets, performing image processing on the acquired data sets and recombining good data from the image processed data sets into a single image of the patient user's body part.

Abstract: A method for combining a plurality of eye images into a plenoptic multifocal image that includes registering the eye images with a plurality of frames into one or more eye image sets with a processor and a memory system, aligning each of the eye images in each of the one or more image sets with a selected reference that resides on the memory system with the processor and determining one or more in-focus regions of the eye images by calculating one or more gradient images while ignoring noise and other imaging artifacts. The method also includes identifying the one or more in-focus regions with highest resolution from the one or more gradient images and selecting one or more corresponding in-focus intensities from the frames to combine into a plenoptic multifocal image with a higher resolution than the eye images, the frames and the one or more eye image sets.

Abstract: A slit lamp mounted eye imaging a slit lamp integrated, a handheld, OCT integrated, or attached to a separate chinrest-joystick assembly apparatus for producing a wide field and/or magnified views of the posterior or the anterior segments of an eye through an undilated or dilated pupil. The apparatus images sections and focal planes and utilizes an illumination system that uses one or more LEDs, shifting optical elements, flipping masks, and/or aperture stops where the light can be delivered into the optical system on optical axis or off axis from center of optical system and return imaging path from the eye, creating artifacts in different locations on the eye image. Image processing is employed to detect and eliminate artifacts and masks from images. The apparatus can be used in combination with an OCT, microscope and can be disposed in a hand-held housing for hand-held use.

Abstract: A slit lamp mounted eye imaging a slit lamp integrated, a handheld, OCT integrated, or attached to a separate chinrest-joystick assembly apparatus for producing a wide field and/or magnified views of the posterior or the anterior segments of an eye through an undilated or dilated pupil. The apparatus images sections and focal planes and utilizes an illumination system that uses one or more LEDs, shifting optical elements, flipping masks, and/or aperture stops where the light can be delivered into the optical system on optical axis or off axis from center of optical system and return imaging path from the eye, creating artifacts in different locations on the eye image. Image processing is employed to detect and eliminate artifacts and masks from images. The apparatus can be used in combination with an OCT, microscope and can be disposed in a hand-held housing for hand-held use.

Abstract: The present invention is an apparatus and method to produce an image of an eye of a patient that includes an optical head that includes imaging optics, illumination source optics and a camera housing with a perimeter that houses the video camera optics and the illumination source optics, a slit lamp chinrest and joystick assembly that includes an adjustable head support, a movable base, a joystick that adjusts a position of the camera housing relative to the head support and the housing support that mounts the video camera, a rubber eyecup that provides an interface between the camera housing and the patient's eye that protrudes outward from the perimeter and a computer system that analyzes images and data for the presence of amyloid in a retina, and other deposits and provides a diagnosis of macular degeneration, Alzheimer's disease, traumatic brain injury, multiple concussive injury, neurodegenerative and other ocular disorders.

Abstract: An eye imaging apparatus to produce an image of an eye of a patient user is disclosed. The eye imaging apparatus may include a video camera, a slit lamp chinrest, a camera housing, a plurality of illumination source optics and a processing system. The eye imaging apparatus may also include a video camera, a plurality of video camera optics, a camera housing, a microscope assembly, a plurality of illumination source optics and a floor base. The eye imaging apparatus may be utilized in combination with one or more contrasting agents. The eye imaging apparatus may detect amyloid-beta plaque, amyloid or amyloid-beta peptide by a spectral signature.

Abstract: The present invention is a slit lamp mounted eye imaging, a slit lamp integrated, a handheld, OCT integrated, or attached to a separate chinrest-joystick assembly apparatus and method for producing a wide field and/or magnified views of the posterior or the anterior segments of an eye through an undilated or dilated pupil. The apparatus images sections and focal planes and utilizes an illumination system that uses one or more LEDs, shifting optical elements, flipping masks, and/or aperture stops where the light can be delivered into the optical system on optical axis or off axis from center of optical system and return imaging path from the eye, creating artifacts in different locations on the eye image. Image processing is employed to detect and eliminate artifacts and masks from images. The apparatus can be used in combination with an OCT, microscope and can be disposed in a hand-held housing for hand-held use.

Abstract: A method for combining a plurality of eye images into a plenoptic multifocal image that includes registering the eye images with a plurality of frames into one or more eye image sets with a processor and a memory system, aligning each of the eye images in each of the one or more image sets with a selected reference that resides on the memory system with the processor and determining one or more in-focus regions of the eye images by calculating one or more gradient images while ignoring noise and other imaging artifacts. The method also includes identifying the one or more in-focus regions with highest resolution from the one or more gradient images and selecting one or more corresponding in-focus intensities from the frames to combine into a plenoptic multifocal image with a higher resolution than the eye images, the frames and the one or more eye image sets.

Abstract: The present invention is an apparatus to produce an OCT of an eye or a brain of a patient to identify one or more plaques in a plurality of discrete OCT retinal layers. The present invention also includes a plurality of methods for identifying one or more plaques in a plurality of discrete OCT retinal layers that can include a contrast agent and a normative database.

Abstract: The present invention is an apparatus and method to produce an image of an eye of a patient that includes an optical head that includes imaging optics, illumination source optics and a camera housing with a perimeter that houses the video camera optics and the illumination source optics, a slit lamp chinrest and joystick assembly that includes an adjustable head support, a movable base, a joystick that adjusts a position of the camera housing relative to the head support and the housing support that mounts the video camera, a rubber eyecup that provides an interface between the camera housing and the patient's eye that protrudes outward from the perimeter and a computer system that analyzes images and data for the presence of amyloid in a retina, and other deposits and provides a diagnosis of macular degeneration, Alzheimer's disease, traumatic brain injury, multiple concussive injury, neurodegenerative and other ocular disorders.

Abstract: The present invention is a slit lamp mounted eye imaging, a slit lamp integrated, a handheld, OCT integrated, or attached to a separate chinrest-joystick assembly apparatus and method for producing a wide field and/or magnified views of the posterior or the anterior segments of an eye through an undilated or dilated pupil. The apparatus images sections and focal planes and utilizes an illumination system that uses one or more LEDs, shifting optical elements, flipping masks, and/or aperture stops where the light can be delivered into the optical system on optical axis or off axis from center of optical system and return imaging path from the eye, creating artifacts in different locations on the eye image. Image processing is employed to detect and eliminate artifacts and masks from images. The apparatus can be used in combination with an OCT, microscope and can be disposed in a hand-held housing for hand-held use.

Abstract: A slit lamp mounted eye imaging device for viewing wide field and/or magnified views of the retina or the anterior segment through an undilated or dilated pupil. The apparatus images posterior and anterior segments of the eye, and sections/focal planes in between and contains an illumination system that uses one or more LEDs, shifting optical elements, and/or aperture stops where the light can be delivered into the optical system on optical axis or off axis from center of optical system and return imaging path from the retina, thereby creating artifacts in different locations on retina. Image processing is employed to detect and eliminate artifacts from images. The device is well suited for retinal imaging through an undilated pupil, non-pharmacologically dilated, or a pupil as small as 2 mm. Two or more images with reflection artifacts can be created and subsequently recombined through image processing into a composite artifact-free image.

Abstract: A slit lamp mounted eye imaging device for viewing wide field and/or magnified views of the retina or the anterior segment through an undilated or dilated pupil. The apparatus images posterior and anterior segments of the eye, and sections/focal planes in between and contains an illumination system that uses one or more LEDs, shifting optical elements, and/or aperture stops where the light can be delivered into the optical system on optical axis or off axis from center of optical system and return imaging path from the retina, thereby creating artifacts in different locations on retina. Image processing is employed to detect and eliminate artifacts from images. The device is well suited for retinal imaging through an undilated pupil, non-pharmacologically dilated, or a pupil as small as 2 mm. Two or more images with reflection artifacts can be created and subsequently recombined through image processing into a composite artifact-free image.