Patents by Inventor Steven Rothstein

Steven Rothstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250092433
    Abstract: Described herein are polypeptides encoding enzymes for the synthesis of monoterpene indole alkaloids. For example, the polypeptide comprises or consists of the sequence of SEQ ID NO: 1-68, or a variant thereof having at least 80% sequence identity to SEQ ID NO: 1-68, or a fragment of the polypeptide, or the variant thereof.
    Type: Application
    Filed: September 20, 2024
    Publication date: March 20, 2025
    Applicant: Mitradyne Corporation
    Inventors: Jose CASARETTO, Tariq A. AKTAR, Steven ROTHSTEIN, Eric SOUBEYRAND
  • Publication number: 20240299478
    Abstract: In aspects, a cannabis extract enriched in polyphenolic compounds is provided herein. Also provided herein is a method for enriching a composition with polyphenolic compounds as well as compositions made by the method. Various cosmetic and pharmaceutical products, methods, and uses are provided herein as well as natural health products.
    Type: Application
    Filed: March 18, 2024
    Publication date: September 12, 2024
    Inventors: Steven ROTHSTEIN, Tariq AKHTAR, Jose CASARETTO, Gale BOZZO, Colby PERRIN, Cameron PARRY
  • Patent number: 12011471
    Abstract: In aspects, a cannabis extract enriched in polyphenolic compounds is provided herein. Also provided herein is a method for enriching a composition with polyphenolic compounds as well as compositions made by the method. Various cosmetic and pharmaceutical products, methods, and uses are provided herein as well as natural health products.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: June 18, 2024
    Assignee: ATLAS365 INCORPORATED
    Inventors: Steven Rothstein, Tariq Akhtar, Jose Casaretto, Gale Bozzo, Colby Perrin, Cameron Parry
  • Publication number: 20240026314
    Abstract: Described herein is a polypeptide encoding a prenyltransferase for prenylating a polyphenol and a polypeptide encoding an O-methyltransferase for methylating a polyphenol. For example, the polypeptide comprises or consists of the sequence of SEQ ID NO: 1, 2, 3, 4, 5, and/or 6, and/or a polypeptide listed in Table 1, and/or SEQ ID NO: 7-30, or a variant thereof having at least 80% sequence identity to SEQ ID NO: 1, 2, 3, 4, 5, and/or 6, and/or the polypeptide listed in Table 1, and/or SEQ ID NO: 7-30, or a fragment of the polypeptide or the variant thereof.
    Type: Application
    Filed: November 24, 2021
    Publication date: January 25, 2024
    Inventors: Steven ROTHSTEIN, Tariq AKHTAR, Jose CASARETTO, Colby PERRIN, Kristen VAN GELDER
  • Publication number: 20230047321
    Abstract: In aspects, a cannabis extract enriched in polyphenolic compounds is provided herein. Also provided herein is a method for enriching a composition with polyphenolic compounds as well as compositions made by the method. Various cosmetic and pharmaceutical products, methods, and uses are provided herein as well as natural health products.
    Type: Application
    Filed: December 18, 2020
    Publication date: February 16, 2023
    Inventors: Steven ROTHSTEIN, Tariq AKHTAR, Jose CASARETTO, Gale BOZZO, Colby PERRIN, Cameron PARRY
  • Publication number: 20150218578
    Abstract: The present invention provides methods of increasing tolerance to high temperature or heat stress in a plant, plant part, or plant cell, the method comprising introducing one or more nucleic acids encoding (i) a glutamine synthetase 1;2 (GS 1;2), (ii) a glutamate decarboxylase 3 (GAD3), (iii) a class I glutamine amidotransferase (GAT1), (iv) a MYB55 polypeptide or any combination thereof into a plant, plant part or plant cell. Also provided are methods of increasing amino acid content in a plant, plant part, or plant cell, the method comprising introducing one or more nucleic acids encoding (i) a GS1;2, (ii) a GAD3, (iii) a GAT1, (iv) a MYB55 polypeptide or any combination thereof into a plant, plant part or plant cell.
    Type: Application
    Filed: March 13, 2013
    Publication date: August 6, 2015
    Applicant: University of Guelph
    Inventors: Steven Rothstein, Ashraf El-kereamy, Yongmei Bi
  • Publication number: 20150203864
    Abstract: The invention provides MYB55 promoter sequences that can advantageously be used to express a nucleotide sequence of interest in a plant, plant part or plant cell. Also provided are methods of increasing the expression of a nucleotide sequence of interest in a plant, plant part or plant cell in response to high temperature, abscisic acid, salicylic acid and/or methyl jasmonate. Further provided are methods of increasing the tolerance of a plant, plant part or plant cell to heat stress using the promoter sequences as described herein.
    Type: Application
    Filed: March 13, 2013
    Publication date: July 23, 2015
    Applicant: University of Guelph
    Inventors: Steven Rothstein, Yongmei Bi, Ashraf El-kereamy
  • Patent number: 8742201
    Abstract: The present invention relates to a nitrogen-regulated GATA transcription factor gene required for sugar sensing and the modulation of the expression of this gene to modulate a characteristic in a plant. The GATA transcription factor of the present invention is involved in regulating sugar sensing in plants and its expression is influenced by nitrogen status. Increased expression of this or substantially similar genes can produce plants with improved nitrogen utilization and increased yield.
    Type: Grant
    Filed: May 6, 2010
    Date of Patent: June 3, 2014
    Assignee: University of Guelph
    Inventors: Steven Rothstein, Yong-Mei Bi
  • Patent number: 8586825
    Abstract: The present invention relates to a nitrogen-regulated GATA transcription factor gene required for sugar sensing and the modulation of the expression of this gene to modulate a characteristic in a plant. The GATA transcription factor of the present invention is involved in regulating sugar sensing in plants and its expression is influenced by nitrogen status. Increased expression of this or substantially similar genes can produce plants with improved nitrogen utilization and increased yield.
    Type: Grant
    Filed: June 29, 2009
    Date of Patent: November 19, 2013
    Assignee: The University of Guelph
    Inventors: Steven Rothstein, Yong-Mei Bi
  • Publication number: 20130074214
    Abstract: Isolated nucleic acids and proteins and plants expressing the same for improved nitrogen utilization, increased yield, and increased stress tolerance.
    Type: Application
    Filed: September 25, 2009
    Publication date: March 21, 2013
    Applicants: University Of Guelph, Syngenta Participations
    Inventors: Surya Kant, Steven Rothstein, Yong-Mei Bi, Joseph Clarke
  • Patent number: 8119598
    Abstract: In joint reconstruction, repair and cushioning applications, a synthetic polypeptide material is useful that contains cross-linked polypeptides that are modeled on human elastin or other fibrous proteins. The polypeptides comprise at least three consecutive beta-sheet/beta-turn structures and at least one amino acid residue that participates in cross-linking.
    Type: Grant
    Filed: May 6, 2008
    Date of Patent: February 21, 2012
    Assignees: Hospital For Sick Children, Elastin Specialties, Inc.
    Inventors: Fred Keeley, Aser Rothstein, Steven Rothstein, Kimberly Woodhouse
  • Publication number: 20110055975
    Abstract: The present invention relates to a nitrogen-regulated GATA transcription factor gene required for sugar sensing and the modulation of the expression of this gene to modulate a characteristic in a plant. The GATA transcription factor of the present invention is involved in regulating sugar sensing in plants and its expression is influenced by nitrogen status. Increased expression of this or substantially similar genes can produce plants with improved nitrogen utilization and increased yield.
    Type: Application
    Filed: May 6, 2010
    Publication date: March 3, 2011
    Applicant: UNIVERSITY OF GUELPH
    Inventors: Steven ROTHSTEIN, Yong-Mei Bi
  • Publication number: 20090328255
    Abstract: The present invention relates to a nitrogen-regulated RING-like ubiquitin E3 ligase gene required for sugar sensing and the modulation of the expression of this gene to modulate a characteristic in a plant. The RING-like ubiquitin E3 ligase of the present invention is involved in mediating nitrogen limitation adaptive responses in plants and its expression is influenced by nitrogen status. Increased expression of this or substantially similar genes can produce plants with improved nitrogen utilization and increased yield.
    Type: Application
    Filed: June 13, 2007
    Publication date: December 31, 2009
    Inventors: Steven Rothstein, Mingsheng Peng, Yong-Mei Bi
  • Publication number: 20090276919
    Abstract: The present invention relates to a nitrogen-regulated GATA transcription factor gene required for sugar sensing and the modulation of the expression of this gene to modulate a characteristic in a plant. The GATA transcription factor of the present invention is involved in regulating sugar sensing in plants and its expression is influenced by nitrogen status. Increased expression of this or substantially similar genes can produce plants with improved nitrogen utilization and increased yield.
    Type: Application
    Filed: June 29, 2009
    Publication date: November 5, 2009
    Applicant: UNIVERSITY OF GUELPH
    Inventors: Steven Rothstein, Yong-Mei Bi
  • Patent number: 7554018
    Abstract: The present invention relates to a nitrogen-regulated GATA transcription factor gene required for sugar sensing and the modulation of the expression of this gene to modulate a characteristic in a plant. The GATA transcription factor of the present invention is involved in regulating sugar sensing in plants and its expression is influenced by nitrogen status. Increased expression of this or substantially similar genes can produce plants with improved nitrogen utilization and increased yield.
    Type: Grant
    Filed: January 13, 2006
    Date of Patent: June 30, 2009
    Assignee: University of Guelph
    Inventors: Steven Rothstein, Yong-Mei Bi
  • Publication number: 20090075868
    Abstract: In joint reconstruction, repair and cushioning applications, a synthetic polypeptide material is useful that contains cross-linked polypeptides that are modeled on human elastin or other fibrous proteins. The polypeptides comprise at least three consecutive beta-sheet/beta-turn structures and at least one amino acid residue that participates in cross-linking.
    Type: Application
    Filed: May 6, 2008
    Publication date: March 19, 2009
    Inventors: Fred Keeley, Aser Rothstein, Steven Rothstein, Kimberly Woodhouse
  • Publication number: 20070250956
    Abstract: The present invention relates to a nitrogen-regulated GATA transcription factor gene required for sugar sensing and the modulation of the expression of this gene to modulate a characteristic in a plant. The GATA transcription factor of the present invention is involved in regulating sugar sensing in plants and its expression is influenced by nitrogen status. Increased expression of this or substantially similar genes can produce plants with improved nitrogen utilization and increased yield.
    Type: Application
    Filed: April 17, 2007
    Publication date: October 25, 2007
    Applicant: University of Guelph
    Inventors: Steven Rothstein, Yong-Mei Bi
  • Publication number: 20060179512
    Abstract: The present invention relates to a nitrogen-regulated GATA transcription factor gene required for sugar sensing and the modulation of the expression of this gene to modulate a characteristic in a plant. The GATA transcription factor of the present invention is involved in regulating sugar sensing in plants and its expression is influenced by nitrogen status. Increased expression of this or substantially similar genes can produce plants with improved nitrogen utilization and increased yield.
    Type: Application
    Filed: January 13, 2006
    Publication date: August 10, 2006
    Inventors: Steven Rothstein, Yong-Mei Bi
  • Publication number: 20060117407
    Abstract: Methods for transformation of maize with nucleic acid sequences of interest are disclosed. The method involves subjecting immature zygotic embryos or Type I callus to high velocity microprojectile bombardment. The method is capable of producing transformed maize lines of commercial importance and their hybrid combinations.
    Type: Application
    Filed: March 2, 2005
    Publication date: June 1, 2006
    Inventors: Michael Koziel, Nalini Desai, Kelly Lewis, Vance Kramer, Gregory Warren, Steve Evola, Lyle Crossland, Martha Wright, Ellis Merlin, Karen Launis, Steven Rothstein, Cindy Boyce, John Dawson, Erik Dunder, Gary Pace, Jan Suttie, Nadine Carozzi, Annick De Framond, James Linder, Robert Miller, Bruce Skillings, Alan Mousel, Albert Hornbrook, Christopher Clucas, Moez Meghji, Andreas Tanner, Francis Cassagne, Gilles Pollini, Terry Colbert, Francis Cammack
  • Publication number: 20060021095
    Abstract: DNA sequences optimized for expression in plants are disclosed. The DNA sequences preferably encode for an insecticidal polypeptides, particularly insecticidal proteins from Bacillus thuringiensis. Plant promoters, particular tissue-specific and tissue-preferred promoters are also provided. Additionally disclosed are transformation vectors comprising said DNA sequences. The transformation vectors demonstrate high levels of insecticidal activity when transformed into maize.
    Type: Application
    Filed: January 8, 2004
    Publication date: January 26, 2006
    Inventors: Michael Koziel, Nalini Desai, Kelly Lewis, Gregory Warren, Steve Evola, Martha Wright, Karen Launis, Steven Rothstein, Cindy Boyce, John Dawson, Erik Dunder, Gary Pace, Jan Suttie, Nadine Carozzi