Patents by Inventor Steven Ruggiero
Steven Ruggiero has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9657336Abstract: Methods and systems of quantifying a target material in solution include detection of a size change of a hybridized nanoparticle. In particular, the examples include functionalizing a plurality of nanoparticles to adapt the nanoparticles to hybridize with a species-specific target material, measuring the size of the functionalized nanoparticles to predetermine a standard distribution of non-hybridized nanoparticles, introducing the functionalized nanoparticles in a solution containing species-specific target materials and/or non-target materials, and hybridizing the functionalized nanoparticles with the species-specific target material if present in the solution. The size of the nanoparticles in solution are then measured after hybridization, and the presence or non-presence of the species-specific target material is detected and/or quantified by comparing the measured size of the nanoparticles after hybridization to the standard distribution of non-hybridized nanoparticles.Type: GrantFiled: April 25, 2012Date of Patent: May 23, 2017Assignee: University of Notre Dame Du LacInventors: Steven Ruggiero, Carol Tanner
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Patent number: 9447456Abstract: Methods and systems of quantifying a target material in solution include detection of a size change of a hybridized nucleic acid complex, without the use of nanobeads. In particular, the examples include providing a plurality of nucleic acid fragments and a species-specific oligonucleotide tags, measuring the size of the nucleic acid fragments and/or oligonucleotides to predetermine a standard distribution of the solution(s), introducing the oligonucleotides in a solution containing nucleic acid target materials and/or non-target materials, and hybridizing the oligonucleotides with the species-specific target material if present in the solution. The size of the nucleic acid complexes in solution are then measured after hybridization, and the presence or non-presence of the species-specific target material is detected and/or quantified by comparing the measured size of the nucleic acid complexes after hybridization to the standard distribution.Type: GrantFiled: September 12, 2012Date of Patent: September 20, 2016Assignee: University of Notre Dame du LacInventors: Carol Tanner, Steven Ruggiero
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Patent number: 9366612Abstract: An apparatus for obtaining suspended particle information includes an optical array to divide light to a first path and a second path, a platform to orient a first and second container with either the first or second path, and a first and second photodetector to receive at least a direct illuminating component of the light of the first and second path after said light penetrates through the first and second container. A detector interface receives transmission signals from the first and second photodetectors of the direct illuminating component of the light after penetrating through the first and second container and a calculation engine computes the particle information based on a ratio of the received transmission signals.Type: GrantFiled: September 18, 2014Date of Patent: June 14, 2016Assignee: University of Notre Dame du LacInventors: Steven Ruggiero, Carol Tanner
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Publication number: 20150070696Abstract: An apparatus for obtaining suspended particle information includes an optical array to divide light to a first path and a second path, a platform to orient a first and second container with either the first or second path, and a first and second photodetector to receive at least a direct illuminating component of the light of the first and second path after said light penetrates through the first and second container. A detector interface receives transmission signals from the first and second photodetectors of the direct illuminating component of the light after penetrating through the first and second container and a calculation engine computes the particle information based on a ratio of the received transmission signals.Type: ApplicationFiled: September 18, 2014Publication date: March 12, 2015Inventors: Steven Ruggiero, Carol Tanner
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Patent number: 8867039Abstract: Example methods and apparatus for obtaining suspended particle information are disclosed. A disclosed example method includes emitting light from a light source, dividing the light source into a first path and a second path, and directing the first path to a first container comprising a plurality of particles in a suspension material. The example method also includes directing the second path to a second container containing a suspension material devoid of particles, retrieving a first transmission value of the first path through the first container, and retrieving a second transmission value of the second path through the second container.Type: GrantFiled: June 3, 2013Date of Patent: October 21, 2014Assignee: University of Notre Dame du LacInventors: Steven Ruggiero, Carol Tanner
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Publication number: 20140120539Abstract: Methods and systems of quantifying a target material in solution include detection of a size change of a hybridized nucleic acid complex, without the use of nanobeads. In particular, the examples include providing a plurality of nucleic acid fragments and a species-specific oligonucleotide tags, measuring the size of the nucleic acid fragments and/or oligonucleotides to predetermine a standard distribution of the solution(s), introducing the oligonucleotides in a solution containing nucleic acid target materials and/or non-target materials, and hybridizing the oligonucleotides with the species-specific target material if present in the solution. The size of the nucleic acid complexes in solution are then measured after hybridization, and the presence or non-presence of the species-specific target material is detected and/or quantified by comparing the measured size of the nucleic acid complexes after hybridization to the standard distribution.Type: ApplicationFiled: September 12, 2012Publication date: May 1, 2014Applicant: University of Notre Dame du LacInventors: Carol Tanner, Steven Ruggiero
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Publication number: 20140045722Abstract: Methods and systems of quantifying a target material in solution include detection of a size change of a hybridized nanoparticle. In particular, the examples include functionalizing a plurality of nanoparticles to adapt the nanoparticles to hybridize with a species-specific target material, measuring the size of the functionalized nanoparticles to predetermine a standard distribution of non-hybridized nanoparticles, introducing the functionalized nanoparticles in a solution containing species-specific target materials and/or non-target materials, and hybridizing the functionalized nanoparticles with the species-specific target material if present in the solution. The size of the nanoparticles in solution are then measured after hybridization, and the presence or non-presence of the species-specific target material is detected and/or quantified by comparing the measured size of the nanoparticles after hybridization to the standard distribution of non-hybridized nanoparticles.Type: ApplicationFiled: April 25, 2012Publication date: February 13, 2014Applicant: UNIVERSITY OF NOTRE DAME DU LACInventors: Steven Ruggiero, Carol Tanner
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Publication number: 20140022545Abstract: Example methods and apparatus for obtaining suspended particle information are disclosed. A disclosed example method includes emitting light from a light source, dividing the light source into a first path and a second path, and directing the first path to a first container comprising a plurality of particles in a suspension material. The example method also includes directing the second path to a second container containing a suspension material devoid of particles, retrieving a first transmission value of the first path through the first container, and retrieving a second transmission value of the second path through the second container.Type: ApplicationFiled: June 3, 2013Publication date: January 23, 2014Applicant: UNIVERSITY OF NOTRE DAME DU LACInventors: Steven Ruggiero, Carol Tanner
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Patent number: 8456635Abstract: Example methods and apparatus for obtaining suspended particle information are disclosed. A disclosed example method includes emitting light from a light source, dividing the light source into a first path and a second path, and directing the first path to a first container comprising a plurality of particles in a suspension material. The example method also includes directing the second path to a second container containing a suspension material devoid of particles, retrieving a first transmission value of the first path through the first container, and retrieving a second transmission value of the second path through the second container.Type: GrantFiled: October 23, 2009Date of Patent: June 4, 2013Assignee: University of Notre Dame Du LacInventors: Steven Ruggiero, Carol Tanner
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Publication number: 20110249254Abstract: Example methods and apparatus for obtaining suspended particle information are disclosed. A disclosed example method includes emitting light from a light source, dividing the light source into a first path and a second path, and directing the first path to a first container comprising a plurality of particles in a suspension material. The example method also includes directing the second path to a second container containing a suspension material devoid of particles, retrieving a first transmission value of the first path through the first container, and retrieving a second transmission value of the second path through the second container.Type: ApplicationFiled: October 23, 2009Publication date: October 13, 2011Inventors: Steven Ruggiero, Carol Tanner
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Patent number: 5251268Abstract: An apparatus and method for recognizing written items including characters and symbols is disclosed. A scanner is utilized for scanning the characters and symbols. A recognition module is used to confidently identify the scanned characters and symbols. The recognition module includes a mechanism for recognizing characters. This mechanism includes a character recognition rule base which yields identified characters and unidentified characters. The unidentified characters are conveyed to neural networks for recognition. The recognition module also includes a mechanism for recognizing symbols. This mechanism includes a symbol recognition rule base which yields identified symbols and unidentified symbols. The unidentified symbols are conveyed to neural networks for recognition. The recognition module also includes a mechanism for context processing of the characters and symbols. The context processor utilizes a multilevel blackboard with a number of ascending levels.Type: GrantFiled: August 9, 1991Date of Patent: October 5, 1993Assignee: Electric Power Research Institute, Inc.Inventors: Robert W. Colley, Parvathy Bhaskaran, Alan Filipski, Robert Flandrena, Tad Krolik, Mark Janney, Steven Ruggiero