Patents by Inventor Steven Ruggiero

Steven Ruggiero has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9657336
    Abstract: Methods and systems of quantifying a target material in solution include detection of a size change of a hybridized nanoparticle. In particular, the examples include functionalizing a plurality of nanoparticles to adapt the nanoparticles to hybridize with a species-specific target material, measuring the size of the functionalized nanoparticles to predetermine a standard distribution of non-hybridized nanoparticles, introducing the functionalized nanoparticles in a solution containing species-specific target materials and/or non-target materials, and hybridizing the functionalized nanoparticles with the species-specific target material if present in the solution. The size of the nanoparticles in solution are then measured after hybridization, and the presence or non-presence of the species-specific target material is detected and/or quantified by comparing the measured size of the nanoparticles after hybridization to the standard distribution of non-hybridized nanoparticles.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: May 23, 2017
    Assignee: University of Notre Dame Du Lac
    Inventors: Steven Ruggiero, Carol Tanner
  • Patent number: 9447456
    Abstract: Methods and systems of quantifying a target material in solution include detection of a size change of a hybridized nucleic acid complex, without the use of nanobeads. In particular, the examples include providing a plurality of nucleic acid fragments and a species-specific oligonucleotide tags, measuring the size of the nucleic acid fragments and/or oligonucleotides to predetermine a standard distribution of the solution(s), introducing the oligonucleotides in a solution containing nucleic acid target materials and/or non-target materials, and hybridizing the oligonucleotides with the species-specific target material if present in the solution. The size of the nucleic acid complexes in solution are then measured after hybridization, and the presence or non-presence of the species-specific target material is detected and/or quantified by comparing the measured size of the nucleic acid complexes after hybridization to the standard distribution.
    Type: Grant
    Filed: September 12, 2012
    Date of Patent: September 20, 2016
    Assignee: University of Notre Dame du Lac
    Inventors: Carol Tanner, Steven Ruggiero
  • Patent number: 9366612
    Abstract: An apparatus for obtaining suspended particle information includes an optical array to divide light to a first path and a second path, a platform to orient a first and second container with either the first or second path, and a first and second photodetector to receive at least a direct illuminating component of the light of the first and second path after said light penetrates through the first and second container. A detector interface receives transmission signals from the first and second photodetectors of the direct illuminating component of the light after penetrating through the first and second container and a calculation engine computes the particle information based on a ratio of the received transmission signals.
    Type: Grant
    Filed: September 18, 2014
    Date of Patent: June 14, 2016
    Assignee: University of Notre Dame du Lac
    Inventors: Steven Ruggiero, Carol Tanner
  • Publication number: 20150070696
    Abstract: An apparatus for obtaining suspended particle information includes an optical array to divide light to a first path and a second path, a platform to orient a first and second container with either the first or second path, and a first and second photodetector to receive at least a direct illuminating component of the light of the first and second path after said light penetrates through the first and second container. A detector interface receives transmission signals from the first and second photodetectors of the direct illuminating component of the light after penetrating through the first and second container and a calculation engine computes the particle information based on a ratio of the received transmission signals.
    Type: Application
    Filed: September 18, 2014
    Publication date: March 12, 2015
    Inventors: Steven Ruggiero, Carol Tanner
  • Patent number: 8867039
    Abstract: Example methods and apparatus for obtaining suspended particle information are disclosed. A disclosed example method includes emitting light from a light source, dividing the light source into a first path and a second path, and directing the first path to a first container comprising a plurality of particles in a suspension material. The example method also includes directing the second path to a second container containing a suspension material devoid of particles, retrieving a first transmission value of the first path through the first container, and retrieving a second transmission value of the second path through the second container.
    Type: Grant
    Filed: June 3, 2013
    Date of Patent: October 21, 2014
    Assignee: University of Notre Dame du Lac
    Inventors: Steven Ruggiero, Carol Tanner
  • Publication number: 20140120539
    Abstract: Methods and systems of quantifying a target material in solution include detection of a size change of a hybridized nucleic acid complex, without the use of nanobeads. In particular, the examples include providing a plurality of nucleic acid fragments and a species-specific oligonucleotide tags, measuring the size of the nucleic acid fragments and/or oligonucleotides to predetermine a standard distribution of the solution(s), introducing the oligonucleotides in a solution containing nucleic acid target materials and/or non-target materials, and hybridizing the oligonucleotides with the species-specific target material if present in the solution. The size of the nucleic acid complexes in solution are then measured after hybridization, and the presence or non-presence of the species-specific target material is detected and/or quantified by comparing the measured size of the nucleic acid complexes after hybridization to the standard distribution.
    Type: Application
    Filed: September 12, 2012
    Publication date: May 1, 2014
    Applicant: University of Notre Dame du Lac
    Inventors: Carol Tanner, Steven Ruggiero
  • Publication number: 20140045722
    Abstract: Methods and systems of quantifying a target material in solution include detection of a size change of a hybridized nanoparticle. In particular, the examples include functionalizing a plurality of nanoparticles to adapt the nanoparticles to hybridize with a species-specific target material, measuring the size of the functionalized nanoparticles to predetermine a standard distribution of non-hybridized nanoparticles, introducing the functionalized nanoparticles in a solution containing species-specific target materials and/or non-target materials, and hybridizing the functionalized nanoparticles with the species-specific target material if present in the solution. The size of the nanoparticles in solution are then measured after hybridization, and the presence or non-presence of the species-specific target material is detected and/or quantified by comparing the measured size of the nanoparticles after hybridization to the standard distribution of non-hybridized nanoparticles.
    Type: Application
    Filed: April 25, 2012
    Publication date: February 13, 2014
    Applicant: UNIVERSITY OF NOTRE DAME DU LAC
    Inventors: Steven Ruggiero, Carol Tanner
  • Publication number: 20140022545
    Abstract: Example methods and apparatus for obtaining suspended particle information are disclosed. A disclosed example method includes emitting light from a light source, dividing the light source into a first path and a second path, and directing the first path to a first container comprising a plurality of particles in a suspension material. The example method also includes directing the second path to a second container containing a suspension material devoid of particles, retrieving a first transmission value of the first path through the first container, and retrieving a second transmission value of the second path through the second container.
    Type: Application
    Filed: June 3, 2013
    Publication date: January 23, 2014
    Applicant: UNIVERSITY OF NOTRE DAME DU LAC
    Inventors: Steven Ruggiero, Carol Tanner
  • Patent number: 8456635
    Abstract: Example methods and apparatus for obtaining suspended particle information are disclosed. A disclosed example method includes emitting light from a light source, dividing the light source into a first path and a second path, and directing the first path to a first container comprising a plurality of particles in a suspension material. The example method also includes directing the second path to a second container containing a suspension material devoid of particles, retrieving a first transmission value of the first path through the first container, and retrieving a second transmission value of the second path through the second container.
    Type: Grant
    Filed: October 23, 2009
    Date of Patent: June 4, 2013
    Assignee: University of Notre Dame Du Lac
    Inventors: Steven Ruggiero, Carol Tanner
  • Publication number: 20110249254
    Abstract: Example methods and apparatus for obtaining suspended particle information are disclosed. A disclosed example method includes emitting light from a light source, dividing the light source into a first path and a second path, and directing the first path to a first container comprising a plurality of particles in a suspension material. The example method also includes directing the second path to a second container containing a suspension material devoid of particles, retrieving a first transmission value of the first path through the first container, and retrieving a second transmission value of the second path through the second container.
    Type: Application
    Filed: October 23, 2009
    Publication date: October 13, 2011
    Inventors: Steven Ruggiero, Carol Tanner
  • Patent number: 5251268
    Abstract: An apparatus and method for recognizing written items including characters and symbols is disclosed. A scanner is utilized for scanning the characters and symbols. A recognition module is used to confidently identify the scanned characters and symbols. The recognition module includes a mechanism for recognizing characters. This mechanism includes a character recognition rule base which yields identified characters and unidentified characters. The unidentified characters are conveyed to neural networks for recognition. The recognition module also includes a mechanism for recognizing symbols. This mechanism includes a symbol recognition rule base which yields identified symbols and unidentified symbols. The unidentified symbols are conveyed to neural networks for recognition. The recognition module also includes a mechanism for context processing of the characters and symbols. The context processor utilizes a multilevel blackboard with a number of ascending levels.
    Type: Grant
    Filed: August 9, 1991
    Date of Patent: October 5, 1993
    Assignee: Electric Power Research Institute, Inc.
    Inventors: Robert W. Colley, Parvathy Bhaskaran, Alan Filipski, Robert Flandrena, Tad Krolik, Mark Janney, Steven Ruggiero