Abstract: Systems and techniques are described for Alpha channel inter-frame and intra-frame compression. An example method includes receiving a first frame representative of a graphical user interface at a first time and a second frame representative of the graphical user interface at a second time. The example includes dividing the first frame and the second frame into respective blocks. The example includes searching the frames for at least one target block that share a common value with at least one other block in either the first frame and/or the second frame. The example includes applying at least one transform to the at least one target block that references either the common value or the at least one other block in either the first frame and/or the second frame. The example includes replacing the at least one target block with a transform block.