Abstract: The present disclosure involves a method of measuring a physiological feedback from a patient in response to electrical stimulation. A stimulation parameter of a sacral nerve stimulation therapy is ramped up. The sacral nerve stimulation therapy includes electrical pulses generated by a pulse generator based on programming instructions received from an electronic programmer. The electrical pulses are delivered to a patient via a stimulation lead that is implanted in the patient. Via an anal electrode device that is at least partially inserted inside an anal canal of the patient, a compound motor action potential (CMAP) is measured from an anal sphincter of the patient while the stimulation parameter of the sacral nerve stimulation therapy is being ramped up. A stimulation threshold is determined based on the measured CMAP.

Abstract: A color-coded eyeglasses identification system includes a plurality of identification components; at least one eyeglass frame; and a color code placard, including color code designators and designations. A color of an identification component is associated with a characteristic of an eyeglass frame, including an optical power or an owner. When an identification component is installed on an eyeglass frame, a user can identify a characteristic of the eyeglass frame by the installed identification component. Further disclosed is a color-coded eyeglasses apparatus, including an eyeglass frame and at least one identification component.

Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.

Abstract: Surgically implantable drug delivery systems for long-term delivery of haloperidol containing a biodegradable polymer and haloperidol fabricated into the surgically implantable drug delivery systems via solvent casting and compression molding are provided. Also provided are methods for producing the surgically implantable drug delivery systems and methods for using these systems in the treatment of psychotic disorders such as schizophrenia.

Abstract: The present disclosure involves a method of measuring a physiological feedback from a patient in response to electrical stimulation. A stimulation parameter of a sacral nerve stimulation therapy is ramped up. The sacral nerve stimulation therapy includes electrical pulses generated by a pulse generator based on programming instructions received from an electronic programmer. The electrical pulses are delivered to a patient via a stimulation lead that is implanted in the patient. Via an anal electrode device that is at least partially inserted inside an anal canal of the patient, a compound motor action potential (CMAP) is measured from an anal sphincter of the patient while the stimulation parameter of the sacral nerve stimulation therapy is being ramped up. A stimulation threshold is determined based on the measured CMAP.

Abstract: In various examples, an apparatus includes a stimulation lead including an elongate body including a distal end and a proximal end. At least one first electrode is disposed proximate the distal end of the elongate body and is configured to stimulate a first target nerve. At least one second electrode is disposed between the at least one first electrode and the proximal end of the elongate body and is configured to stimulate a second target nerve. At least one first fixation structure is disposed between the at least one second electrode and the proximal end of the elongate body. The at least one first fixation structure is configured to anchor the stimulation lead proximate the sacrum, wherein the at least one first fixation structure is located on the elongate body and spaced a first distance proximally along the elongate body from the at least one first electrode.

Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.

Abstract: Surgically implantable drug delivery systems for long-term delivery of haloperidol containing a biodegradable polymer and haloperidol fabricated into the surgically implantable drug delivery systems via solvent casting and compression molding are provided. Also provided are methods for producing the surgically implantable drug delivery systems and methods for using these systems in the treatment of psychotic disorders such as schizophrenia.

Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.

Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.

Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.

Abstract: This invention is a system and method for a matching system that cross-references patients anonymously with doctors and pharmacies. The invention uses patient-unique biometrics, such as fingerprinting, retinal scanning, or another such unique identifier, for patient identification and verification without revealing a patient's name or other personal information. The system tracks patient prescriptions and produces alerts to indicate potential problems, such as drug interactions or possible fraudulent behavior. The system utilizes the biometric data of the prescribing physician as authorization of the prescription. The system can produce a traceable paper trail, for investigation or prosecution, and protects the medical industry, patients, and the public from the consequences of doctor shopping.

Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.

Abstract: A technique for triggering a system bus write command with user code includes identifying a specific store-type instruction in a user instruction sequence. The specific store-type instruction is converted into a specific request-type command, which is configured to include core permission controls (that are stored in core configuration registers of a processor core by a trusted kernel) and user created data (stored in a cache memory). Slave devices are configured through register space (that is only accessible by the trusted kernel) with respective slave permission controls. The specific request-type command is then transmitted from the cache memory, via a system bus. In this case, the slave devices that receive the specific request-type command process the specific request-type command when the core permission controls are the same as the respective slave permission controls. The trusted kernel may be included in a hypervisor or an operating system.

Abstract: A technique for maintaining input/output (I/O) command ordering on a bus includes assigning a channel identifier to I/O commands of an I/O stream. In this case, the channel identifier indicates the I/O commands belong to the I/O stream. A command location indicator is assigned to each of the I/O commands. The command location indicator provides an indication of which one of the I/O commands is a start command in the I/O stream and which of the I/O commands are continue commands in the I/O stream. The I/O commands are issued in a desired completion order. When a first one of the I/O commands does not complete successfully, the I/O commands in the I/O stream are reissued on the bus starting at the first one of the I/O commands that did not complete successfully.

Abstract: The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.

Abstract: A method, apparatus and computer program product are provided for implementing a pointer and stake model for frame alteration code in a network processor. A current pointer and a stake are provided for a packet selected for transmit. The current pointer is maintained for tracking a current position for frame alteration operations in the packet. The stake is maintained for tracking a start of a current header for frame alteration operations in the packet. The current pointer is used by frame alteration code instructions to specify a sequence of operations relative to the current pointer. The specified frame alteration sequence is compact in terms of code size to operate on data within a small window of bytes. Advance pointer instructions allow the current and stake pointers to be advanced an arbitrary number of bytes into the packet.

Abstract: The decision within a packet processing device to transmit a newly arriving packet into a queue to await further processing or to discard the same packet is made by a flow control method and system. The flow control is updated with a constant period determined by storage and flow rate limits. The update includes comparing current queue occupancy to a threshold. The outcome of the update is adjustment up or down of the transmit probability value. The value is stored for the subsequent period of flow control and packets arriving during that period are subject to a transmit or discard decision that uses that value.

Abstract: This invention is a system and method for a matching system that cross-references patients anonymously with doctors and pharmacies. The invention uses patient-unique biometrics, such as fingerprinting, retinal scanning, or another such unique identifier, for patient identification and verification without revealing a patient's name or other personal information. The system tracks patient prescriptions and produces alerts to indicate potential problems, such as drug interactions or possible fraudulent behavior. The system can produce a traceable paper trail, for investigation or prosecution, and protects the medical industry, patients, and the public from the consequences of doctor shopping.

Abstract: Novel data structures, methods and apparatus for finding the longest prefix match search when searching tables with variable length patterns or prefixes. To find the exact match or the best matching prefix, patterns have to be compared a bit at a time until the exact or first match is found. This requires “n” number of comparisons or memory accesses to identify the closest matching pattern. The trees are built in such a way that the matching result is guaranteed to be a best match, whether it is an exact match or a longest prefix match. Using the trail of all the birds and associated prefix lengths enables determination of the correct prefix result from the trail. By construction, the search tree provides the best matching prefix at or after the first compare during walking of the trail or tree.