Abstract: Spin resonance spectroscopy and/or imaging is achieved using a system that combines longitudinal (e.g., along the z-axis) detection with a modulated fictitious field generated by a transverse plane (e.g., xy-plane) RF field. Based on z-axis detection of magnetization polarized by this fictitious field as it is modulated (e.g., modulated on and off, or otherwise), spin resonance signals (e.g., EPR, NMR) are measurable with high isolation simultaneous transmit and receive capability. Additionally or alternatively, spin relaxation times can be measured using the described systems.

Abstract: A switchable birdcage coil functioning as a transmitter coil and a separate RF surface coil functioning as the receiver coil are utilize in NMR and MRI apparatus. To prevent the switchable birdcage coil from absorbing energy by coupling to the receiver coil or by absorbing power from the RF field produced by the precessing nuclear spins, one or more of the reactive elements of the birdcage coil are switched from a normal reactive impedance state to a high impedance state. The high impedance state is formed by switchably combining the reactive element with a complementary reactive element thereby forming parallel resonant high impedance circuit that is tuned to resonate at the NMR frequency.

Abstract: Methods, systems, devices and computer program products monitor in vivo detected radiation in a target localized site within a subject, over a selected time period, to do one or more of: (a) quantify a radiation dose received at a local site; (b) assess bioreceptiveness to a particular treatment time or type; (c) evaluate the pharmacokinetics of a radiolabeled analyte corresponding to a non-radiolabeled analyte; (d) monitor or evaluate metabolic activity; or (e) evaluate a tumor prior to or after a therapeutic treatment.

Abstract: System for analyzing an in vivo response of a subject include a radiation detector for detecting radiation present in at least one localized solid tissue region of interest in a subject associated with internal activity of an administered quantity of an analyte comprising at least one of C-14 labeled glucose, a C-14 labeled constituent thereof, and a C-14 labeled glucose derivative, in the at least one solid tissue region of interest over a desired time interval of interest; and a reader in communication with the implantable detector for collecting radiation data from the detector associated with the detected radiation to determine at least one of the following; the in vivo dynamic, kinetic, and metabolic response of the subject.

Abstract: Methods, systems, devices and computer program products monitor in vivo detected radiation in a target localized site within a subject, over a selected time period, to do one or more of: (a) quantify a radiation dose received at a local site; (b) assess bioreceptiveness to a particular treatment time or type; (c) evaluate the pharmacokinetics of a radiolabeled analyte corresponding to a non-radiolabeled analyte; (d) monitor or evaluate metabolic activity; or (e) evaluate a tumor prior to or after a therapeutic treatment.