Abstract: The present invention relates to methods of detecting compounds that affect the activity of a therapeutic substance or composition administered to a subject, and to reagents for use in such methods.

Abstract: A microarchitecture and instruction set that supports multiple, simultaneously executing threads. The approach is disclosed in regard to its applicability in connection with a recently developed microarchitecture called “WaveScalar.” WaveScalar is a compiler that breaks a control flow graph for a program into pieces called waves having instructions that are partially ordered (i.e., a wave contains no back-edges), and for which control enters at a single point. Certain aspects of the present approach are also generally applicable to executing multiple threads on a more conventional microarchitecture. In one aspect of this approach, instructions are provided that enable and disable wave-ordered memory. Additional memory access instructions bypass wave-ordered memory, exposing additional parallelism. Also, a lightweight, interthread synchronization is employed that models hardware queue locks. Finally, a simple fence instruction is used to allow applications to handle relaxed memory consistency.

Abstract: A dataflow instruction set architecture and execution model, referred to as WaveScalar, which is designed for scalable, low-complexity/high-performance processors, while efficiently providing traditional memory semantics through a mechanism called wave-ordered memory. Wave-ordered memory enables “real-world” programs, written in any language, to be run on the WaveScalar architecture, as well as any out-of-order execution unit. Because it is software-controlled, wave-ordered memory can be disabled to obtain greater parallelism. Wavescalar also includes a software-controlled tag management system.

Abstract: A method and device is provided for communicating with an access device. The device includes a wireless communications module to communicate with the access device in a wireless fashion, a data storage module to store bulk data, and a controller connected to the communication module and to the data storage module. The controller controls storage of data in the data storage module and retrieval of data from the data storage module in response to requests from a user via the access device. The device may function as a personal server which, for example, communicates with an access device (e.g., PC, PDA, cellular telephone, or the like) using Bluetooth technology. As Bluetooth is a universally accepted communication standard, a variety of different access devices, or any one particular preferred interface, in proximity to the user may be used to define a personal computing environment.

Abstract: Indazolecarboxamides are used as antagonists and partial agonists for the serotonin receptor 5-HT.sub.4 and provide therapeutic methods for treatment of disorders caused by or affected by dysfunction of the 5-HT.sub.4 receptor.

Abstract: Indazolecarboxamides are used as antagonists and partial agonists for the serotonin receptor 5-HT.sub.4 and provide therapeutic methods for treatment of disorders caused by or affected by dysfunction of the 5-HT.sub.4 receptor.

Abstract: Indazolecarboxamides are used as antagonists and partial agonists for the serotonin receptor 5-HT.sub.4 and provide therapeutic methods for treatment of disorders caused by or affected by dysfunction of the 5-HT.sub.4 receptor.