Abstract: Genetically modified non-human animals are provided that may be used to model human hematopoietic cell development, function, or disease. The genetically modified non-human animals comprise a nucleic acid encoding human IL-6 operably linked to an IL-6 promoter. In some instances, the genetically modified non-human animal expressing human IL-6 also expresses at least one of human M-CSF, human IL-3, human GM-CSF, human SIRPa or human TPO. In some instances, the genetically modified non-human animal is immunodeficient. In some such instances, the genetically modified non-human animal is engrafted with healthy or diseased human hematopoietic cells. Also provided are methods for using the subject genetically modified non-human animals in modeling human hematopoietic cell development, function, and/or disease, as well as reagents and kits thereof that find use in making the subject genetically modified non-human animals and/or practicing the subject methods.

Abstract: A thermoplastic elastomer tube can include a thermoplastic elastomer component disposed within a matrix. In an embodiment, the thermoplastic elastomer component is disposed within the matrix in a thermoplastic elastomer phase having a number of domains. At least approximately 50% of the domains of the thermoplastic elastomer component have an aspect ratio of no greater than approximately 1.5. In a particular embodiment, the thermoplastic elastomer tube comprises at least approximately 20 wt % of the thermoplastic elastomer component and no greater than approximately 50 wt % of a polyolefin component. In some embodiments, the thermoplastic elastomer component includes styrene.

Abstract: A method analyzes characteristics of a vehicle driver, especially for insurance purposes. The method is performed by a cooperation of an analyzing vehicle system in a vehicle and a stationary processing unit remote from the vehicle. The analyzing vehicle system determines a driver operation characteristics parameter from the driving vehicle and sends the parameter to the stationary processing unit. The stationary processing unit derives a metric from that parameter as driver operation characteristics.

Abstract: An apparatus comprises a slider configured for heat-assisted magnetic coupled to a controller. The slider comprises a writer, a heater, a near-field transducer, and an optical waveguide for communicating light from a laser diode to the near-field transducer. The controller is configured to set a target pre-write clearance of the slider prior to performing a write operation, set a target write clearance of the slider for performing the write operation, and determine a difference between the target pre-write and write clearances to define a target pre-write clearance offset. The controller is also configured to measure, for a plurality of different target pre-write clearance offsets, a writability metric for the slider while sweeping a laser diode current, and adjust the target pre-write clearance offset so that the writability metric reaches a predetermined threshold. The controller is further configured to perform subsequent write operations using the adjusted target pre-write clearance offset.

Abstract: A camera mounting assembly includes a first bezel configured to be positioned on a first side of a panel of a work vehicle and to support a camera. The camera mounting assembly also includes a second bezel configured to be positioned on a second side of the panel and to couple to the first bezel to support the camera between the first bezel and the second bezel, and to couple the camera mounting assembly to the panel.

Abstract: This invention is directed to aqueous redox flow batteries comprising redox-active metal ligand coordination compounds. The compounds and configurations described herein enable flow batteries with performance and cost parameters that represent a significant improvement over that previous known in the art.

Abstract: Certain example embodiments relate to a highly-concurrent, predictable, fast, self-managed, in-process space for storing data that is hidden away from the garbage collector and its related pauses. More particularly, certain example embodiments relate to improved memory management techniques for computer systems that leverage an off-heap direct-memory data store that is massively scalable and highly efficient. The off-heap store may be provided in connection with a Java-based environment, and garbage collection may be completely or nearly completely avoided for the off-heap store. The off-heap store may be integrated into a tiered storage solution in certain example embodiments.

Abstract: Methods and apparatus for verifying operability of a neurophysiological-based control system include generating a test stimulus that will result in a predetermined neurophysiological response in a user. Neurophysiological brain activity signals obtained from the user in response to the test stimulus are processed to generate a test neurophysiological response. The test neurophysiological response and a predetermined neurophysiological response are compared to determine if the neurophysiological-based control system is operating properly.

Abstract: A cushion (16) for use with a mask (10) in delivering a flow of breathing gas to a user includes a first portion adapted to contact a surface of a user, a second portion adapted to be coupled to a mask shell (18), and a wall portion extending between the first portion and the second portion. The wall portion includes a chamber formed therein, the chamber having one of an electro-rheological fluid or a magneto-rheological fluid disposed therein. The cushion further includes a means (44, 50) for selectively varying the apparent viscosity of the fluid disposed within the chamber.

Abstract: A vehicular camera assembly for a vehicle vision system includes front and rear housing members, a lens assembly and a circuit board. An imaging element is disposed on a first side of the circuit board and a plurality of electrical connectors is disposed on a second side of the circuit board. The front housing member includes a lens assembly receiving portion and a circuit board attachment portion. With the circuit board attached at the front housing member and with the lens assembly received at the lens assembly receiving portion, the lens assembly and the imaging element are distanced from one another, and images are focused on the imaging element by the lens assembly. The front housing member and the rear housing member are configured to be attached together. With the front and rear housing members attached together, outer walls of the front and rear housing members enclose the circuit board.

Abstract: An inflation device including a handle mechanism configured to selectively engage and disengage threads within the device. In some instances the threads are configured to couple a plunger to a syringe body. The handle mechanism may be configured to (1) provide a mechanical advantage and (2) change the location and direction of the input force, thereby making the device easier to use.

Abstract: A composition of matter includes: a first composition and a second composition configured to react with each other and provide an epoxy-based binder system; and aggregate for being disbursed into the binder system to provide a material; wherein a moisture content of the aggregate is controlled according to a desired strength for cured material. A method of application of the resulting epoxy based material is disclosed.

Abstract: There is provided a system and method for inducing a reply from a first client connected to a virtual world to facilitate a social interaction using a second client connected to the virtual world. There is provided a method for inducing a reply from a first client connected to a virtual world to facilitate a social interaction using a second client connected to the virtual world, the method comprising locating, in the virtual world, an avatar of the second client in a proximity of an avatar of the first client, executing a social action using the avatar of the second client such that the social action is observable by the first client but not observable by the second client, receiving the reply from the first client in response to the social action, and rendering the reply from first client using the avatar of the first client.

Abstract: An apparatus for electroplating metal on a semiconductor substrate with improved azimuthal uniformity includes in one aspect: a plating chamber configured to contain an electrolyte and an anode; a substrate holder configured to hold the semiconductor substrate; an ionically resistive ionically permeable element (“the element”) configured to be positioned proximate the substrate; and a shield configured for providing azimuthally asymmetrical shielding and positioned between the substrate holder and the element such that the closest distance between the substrate-facing surface of the shield and the working surface of the substrate is less than 2 mm. In some embodiments there is an electrolyte-filled gap between the substrate-facing surface of the element and the shield during electroplating. The substrate-facing surface of the shield may be contoured such that the distance from different positions of the shield to the substrate is varied.

Abstract: A sprinkler includes a compartment that surrounds its riser portion in an offset or asymmetrical configuration. More specifically, the distance of the compartments walls from those of the riser vary (i.e., increase or decrease) at different locations surrounding the riser. Put another way, the riser is closer to one side of the compartment than other sides of the compartment. This non-concentric configuration allows larger components to fit inside the compartment than would otherwise fit if the riser was symmetrically surrounded by the compartment.