Abstract: Process for preparing (S)—N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a] pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide (formula I) or a salt thereof by reacting phenyl(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3,3a-dihydropyrazolo[1,5-a]pyrimidin-3-yl)carbamate or a similar derivative (formula 13) with (S)-pyrrolidin-3-ol (formula 14). Process for preparing phenyl(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3,3a-dihydropyrazolo[1,5-a]pyrimidin-3-yl)carbamate (formula 13) or a similar derivative by reduction of (R)-5-(2-(2,5-difluorophenyl) pyrrolidin-1-yl)-3-nitropyrazolo[1,5-a]pyrimidine (formula 11) to (R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-amine (formula 12). Process for preparing (R)-2-(2,5-difluorophenyl)pyrrolidine(R)-2-hydroxysuccinate (formula 10) by treating (R)—N—((R)-1-(2,5-difluorophenyl)-3-(1,3-dioxan-2-yl)propyl)-2-methylpropane-2-sulfinamide (formula 19) with an acid and a reducing agent.

Abstract: A reduced length ecology tab is provided for a can end. The can end includes an end panel and a rivet affixing the tab to the end panel. The tab includes a body having first and second opposing ends, and a length measured by the distance between the first end and the second end. A nose portion is disposed at or about the first end, and a lift portion is disposed at or about the second end. The length of the tab is less than 0.985 inch.

Abstract: The purpose of this device is to reduce the fuel consumption of heavy trucks by improving airflow past trailer axles. Rather than restrict airflow to the side of the vehicle, diffusers streamline its aerodynamic profile and allow air to flow smoothly beneath. A series of panels mounted to each axle of a truck and trailer forms a substantially continuous surface from the front to the rear axle, promoting laminar flow to the aft of the vehicle, minimizing the effect of suction drag.

Abstract: Technologies are disclosed herein for optimizing in-application purchase (IAP) items to achieve a developer-specified success metric. Application developers can define customer segments and a success metric for each segment. In-application purchase items (IAP) for an application can be tuned for each customer segment in an attempt to achieve the defined success metric. The disclosed techniques can automatically determine the most compelling combination of attributes for an IAP item, such as item price, behavior, definition, and timing. Based on contextual information received from a number of resources, such as an application store, an e-commerce system, and a user device, an optimization service can modify attributes of the IAP items for users in the customer segment to achieve the developer-specified success metrics.

Abstract: Technology is described for augmenting medical imaging for use in a medical procedure. The method can include the operation of receiving an image of patient anatomy captured by a visual image camera during the medical procedure. An acquired medical image associated with the patient anatomy can then be retrieved. Another operation can be associating the acquired medical image to the patient anatomy. An augmentation tag associated with a location in one layer of the acquired medical image can be retrieved. A further operation can be projecting the acquired medical image and the augmentation tag using an augmented reality headset to form a single graphical view as an overlay to the patient anatomy in either 2D, 3D or holographic form.

Abstract: An AR headset is described to co-localize an image data set with a body of a person. One method can include identifying optical codes with a contrast medium in a tubing on the body of the person using the AR headset. The image data set can be aligned with the body of the person using the fixed position of the image visible marker with the contrast medium in the tubing with respect to the optical code referenced to a representation of the image visible marker. In one configuration, an image data set can be scaled by comparing a measured size of the image visible marker (e.g., gadolinium tubing) in the captured image data set to the known size of the image visible marker. In addition, a center of an optical code may be identified to more accurately align the image data set with a body of a person.

Abstract: A system that is capable of controlling multiple entertainment systems and/or speakers using voice commands. The system receives voice commands and may determine audio sources and speakers indicated by the voice commands. The system may generate audio data from the audio sources and may send the audio data to the speakers using multiple interfaces. For example, the system may send the audio data directly to the speakers using a network address, may send the audio data to the speakers via a voice-enabled device or may send the audio data to the speakers via a speaker controller. The system may generate output zones including multiple speakers and may associate input devices with speakers within the output zones. For example, the system may receive a voice command from an input device in an output zone and may reduce output audio generated by speakers in the output zone.

Abstract: A method for disabling a device associated with a virtual identity may include receiving, from the device, a request to use the virtual identity, where the request that may include a passcode guess and a device identifier. The method may also include determining that the passcode guess does not authorize use of the virtual identity and incrementing a number of incorrect passcode guesses received within a time interval. The method may additionally include determining that the number of incorrect passcode guesses received within the time interval is greater than or equal to a threshold. The method may further include storing an indication that subsequent requests associated with the device identifier should not authorize use of the virtual identity.

Abstract: A system and method of additively manufacturing a part via salt micro-spheres. The method includes mixing salt micro-spheres with an additive manufacturing material to form an additive manufacturing material mixture. The additive manufacturing material mixture is deposited on a build platform layer by layer and cured so as to create a structure having pores formed by the salt micro-spheres. The salt micro-spheres may then be dissolved and flushed from the pores.

Abstract: A method of manufacturing comingled yarn of carbon and thermofusible fibres comprises the steps of: feeding a tow of thermofusible fibres from a spool to a blending roller and between the spool and the blending roller, spreading the thermofusible tow; feeding a tow of carbon fibres from a spool to the blending roller; spreading the carbon fibre tow between the spool and the blending roller by applying a flow of air over the tow to urge the tow against a supporting surface over which the carbon fibres pass on their way to the blending roller; combining the thermofusible and carbon fibre tows at the blending roller.

Abstract: A retainer assembly includes a retaining member assembly and a motion assembly. The retaining member assembly is structured to selectively retain at least one shell in a transfer belt assembly belt recess. The retaining member assembly includes a retaining member. The motion assembly is structured to move the retaining member between a first position, wherein the retaining member is spaced from the transfer belt assembly transfer belt, and, a second position, wherein the retaining member is disposed a retaining distance from the transfer belt assembly transfer belt.

Abstract: A can end includes a center panel, an annular portion disposed about the center panel, a chuck wall disposed about the annular portion, a curl extending radially outwardly from the chuck wall, the annular portion including a subsurface step.

Abstract: Technology is described for augmenting medical imaging for use in a medical procedure. The method can include the operation of receiving an image of patient anatomy captured by a visual image camera during the medical procedure. An acquired medical image associated with the patient anatomy can then be retrieved. Another operation can be associating the acquired medical image to the patient anatomy. An augmentation tag associated with a location in one layer of the acquired medical image can be retrieved. A further operation can be projecting the acquired medical image and the augmentation tag using an augmented reality headset to form a single graphical view as an overlay to the patient anatomy in either 2D, 3D or holographic form.

Abstract: A glide rack assembly removably installable within a cooking chamber. The assembly includes a support rack, an engagement member extending downward therefrom and being translatable between a fully retracted position and an extended position, and a locking arm. The locking arm is configured such that when the support rack is in the fully retracted position, the engagement member deflects said locking arm into an unlocked position wherein the locking arm does not cooperate with an embossment on a side wall of the cooking chamber. Further, when the support rack is translated from the fully retracted position, the engagement member does not deflect the locking arm such that the locking arm pivots to a locked position wherein the locking arm cooperates with the embossment such that the assembly is inhibited from being removed.