Patents by Inventor Steven V. Beer

Steven V. Beer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100242358
    Abstract: The present invention relates to a method of imparting pathogen resistance to plants. This involves applying a hypersensitive response elicitor polypeptide or protein in a non-infectious form to a plant seed under conditions where the polypeptide or protein contacts cells of the plant seed. The present invention is also directed to a pathogen resistance imparting plant seed. Alternatively, transgenic plant seeds containing a DNA molecule encoding a hypersensitive response elicitor polypeptide or protein can be planted in soil and a plant can be propagated from the planted seed under conditions effective to impart pathogen resistance to the plant.
    Type: Application
    Filed: October 5, 2009
    Publication date: September 30, 2010
    Inventors: Dewen Qiu, Zhong-Min Wei, Steven V. Beer
  • Publication number: 20090044296
    Abstract: The present invention relates to nucleic acid molecules configured to increase or decrease expression of a nucleic acid molecule that encodes a HrpN-interacting protein; nucleic acid constructs that include these nucleic acid molecules; host cells, transgenic plants, and transgenic plant seeds transformed thereby; and methods of increasing plant growth or imparting disease resistance to plants. Also disclosed are an isolated HIPM nucleic acid molecule and an isolated HIPM protein or polypeptide.
    Type: Application
    Filed: August 7, 2007
    Publication date: February 12, 2009
    Applicant: CORNELL RESEARCH FOUNDATION, INC.
    Inventors: Steven V. BEER, Ray J. WU, Chang-Sik OH
  • Patent number: 7132525
    Abstract: Isolated fragments of an Erwinia hypersensitive response elicitor protein or polypeptide that elicit a hypersensitive response in plants and isolated DNA molecules that encode those fragments are disclosed. Isolated fragments of hypersensitive response elicitor proteins or polypeptides, which elicit a hypersensitive response, and the isolated DNA molecules that encode them can be used to impart disease resistance to plants, to enhance plant growth, and/or to control insects on plants, either by applying the hypersensitive response eliciting fragments to plants or plant seeds or by providing transgenic plants or plant seeds transformed with a DNA molecule encoding a hypersensitive response eliciting fragment.
    Type: Grant
    Filed: March 12, 2003
    Date of Patent: November 7, 2006
    Assignees: Cornell Research Foundation, Inc., Eden BioScience Corporation
    Inventors: Ron J. Laby, Zhong-Min Wei, Steven V. Beer
  • Patent number: 7041876
    Abstract: The present invention relates to a chimeric gene that includes a first DNA molecule encoding a hypersensitive response elicitor protein or polypeptide, a promoter operably linked 5? to the first DNA molecule to induce transcription of the first DNA molecule in response to activation of the promoter by an oomycete, and a 3? regulatory region operably linked to the first DNA molecule. Also disclosed are an expression system and a host cell containing the chimeric gene. The present invention also relates to a transgenic plant resistant to disease resulting from oomycete infection, the transgenic plant including the chimeric gene, wherein the promoter induces transcription of the first DNA molecule in response to infection of the plant by an oomycete. Transgenic seeds and transgenic cultivars obtained from the transgenic plant are also disclosed. Additional aspects of the present invention include methods of making a recombinant plant cell and a transgenic plant.
    Type: Grant
    Filed: January 26, 2001
    Date of Patent: May 9, 2006
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Steven V. Beer, David W. Bauer
  • Patent number: 7029667
    Abstract: The present invention is directed to an isolated DNA molecule from Erwinia amylovora that encodes a protein or polypeptide which elicits a hyersensitive response in plants. This isolated DNA molecule can used to impart disease resistance to plants, to enhance plant growth, and/or to control insects on plants. Plants or plant seeds transformed with a DNA molecule encoding a hypersensitive response elicitor protein or polypeptide can be provided and the transgenic plants or plants resulting from the transgenic plant seeds are grown under conditions effective to impart disease resistance, to enhance plant growth, and/or to control insects on plants or plants grown from the plant seeds.
    Type: Grant
    Filed: June 20, 2000
    Date of Patent: April 18, 2006
    Assignee: Cornell Research Foundation Inc.
    Inventors: Jihyun Francis Kim, Steven V. Beer
  • Patent number: 6998515
    Abstract: The present invention relates to a method of enhancing growth in plants. Transgenic plants or transgenic plant seeds transformed with a DNA molecule encoding a hypersensitive response elicitor polypeptide or protein are grown and, optionally, the transgenic plants or plants resulting from the transgenic plant seeds further have the hypersensitive response elicitor polypeptide or protein applied to them.
    Type: Grant
    Filed: June 20, 2000
    Date of Patent: February 14, 2006
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Dewen Qiu, Zhong-Min Wei, Steven V. Beer
  • Patent number: 6858707
    Abstract: The present invention is directed to isolated active fragments of a hypersensitive response elicitor protein or polypeptide which fragment does not elicit a hypersensitive response in plants. Also disclosed are isolated DNA molecules which encode such fragments. Isolated fragments of hypersensitive response elicitor proteins or polypeptides in accordance with the present invention and the isolated DNA molecules that encode them have the following activities: imparting disease resistance to plants, enhancing plant growth, and/or controlling insects on plants. This can be achieved by applying the fragments of a hypersensitive response elicitor in a non-infectious form to plants or plant seeds under conditions effective to impart disease resistance, to enhance plant growth, and/or to control insects on plants or plants grown from the plant seeds.
    Type: Grant
    Filed: October 4, 1999
    Date of Patent: February 22, 2005
    Assignees: EDEN Bioscience Corporation, Cornell Research Foundation, Inc.
    Inventors: Zhong-Min Wei, Hao Fan, Jennifer J. Stephens, Steven V. Beer, Ron J. Laby
  • Patent number: 6855683
    Abstract: The present invention is directed to an isolated protein or polypeptide which elicits a hypersensitive response in plants as well as an isolated DNA molecule which encodes the hypersensitive response eliciting protein or polypeptide. This isolated protein or polypeptide and the isolated DNA molecule can used to impart disease resistance to plants, to enhance plant growth, and/or to control insects on plants. This can be achieved by applying the hypersensitive response elicitor protein or polypeptide in a non-infectious form to plants or plant seeds under conditions effective to impart disease resistance, to enhance plant growth, and/or to control insects on plants or plants grown from the plant seeds.
    Type: Grant
    Filed: June 19, 2000
    Date of Patent: February 15, 2005
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Adam J. Bogdanove, Jihyun Francis Kim, Zhong-Min Wei, Steven V. Beer
  • Publication number: 20030182683
    Abstract: Isolated fragments of an Erwinia hypersensitive response elicitor protein or polypeptide that elicit a hypersensitive response in plants and isolated DNA molecules that encode those fragments are disclosed. Isolated fragments of hypersensitive response elicitor proteins or polypeptides, which elicit a hypersensitive response, and the isolated DNA molecules that encode them can be used to impart disease resistance to plants, to enhance plant growth, and/or to control insects on plants, either by applying the hypersensitive response eliciting fragments to plants or plant seeds or by providing transgenic plants or plant seeds transformed with a DNA molecule encoding a hypersensitive response eliciting fragment.
    Type: Application
    Filed: March 12, 2003
    Publication date: September 25, 2003
    Inventors: Ron J. Laby, Zhong-Min Wei, Steven V. Beer
  • Patent number: 6596509
    Abstract: One aspect of the present invention relates to a DNA construct that contains a first DNA molecule encoding a functional type III secretion system, a promoter, and a second DNA molecule encoding a protein or polypeptide capable of being secreted by the type III secretion system. The second DNA molecule is operably coupled to the promoter so that upon introduction of the DNA construct into a host cell, the encoded protein or polypeptide and the type III secretion system are expressed and the encoded protein or polypeptide is secreted. Another aspect of the present invention relates to a system that includes (i) a first DNA construct having a first DNA molecule encoding a functional type III secretion system and (ii) a second DNA construct having a promoter operably coupled to a second DNA molecule encoding a protein or polypeptide capable of being secreted by the type III secretion system.
    Type: Grant
    Filed: July 9, 1999
    Date of Patent: July 22, 2003
    Assignee: Cornell Research Foundation, Inc.
    Inventors: David W. Bauer, Steven V. Beer, Adam J. Bogdanove, Alan Collmer, Jong Hyun Ham
  • Patent number: 6583107
    Abstract: The present invention is directed to isolated fragments of an Erwinia hypersensitive response elicitor protein or polypeptide which fragments elicit a hypersensitive response in plants. Also disclosed are isolated DNA molecules which encode the Erwinia hypersensitive response eliciting fragment. Isolated fragments of hypersensitive response elicitor proteins or polypeptides, which elicit a hypersensitive response, and the isolated DNA molecules that encode them can used to impart disease resistance to plants, to enhance plant growth, and/or to control insects on plants. This can be achieved by applying the hypersensitive response eliciting fragments in a non-infectious form to plants or plant seeds under conditions effective to impart disease resistance, to enhance plant growth, and/or to control insects on plants or plants grown from the plant seeds.
    Type: Grant
    Filed: May 28, 1998
    Date of Patent: June 24, 2003
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Ron J. Laby, Zhong-Min Wei, Steven V. Beer
  • Patent number: 6485977
    Abstract: The present invention relates to a method for delivering effector proteins into a target cell. This method involves introducing into the target cell an effector protein fused to a protein transduction domain of a human immunodeficiency virus TAT protein or derivatives or functional analogs thereof. The present invention also relates to a fusion protein including an effector protein fused to a protein transduction domain of a human immunodeficiency virus TAT protein or derivatives or functional analogs thereof. Another aspect of the present invention relates to a DNA construct including a first DNA molecule encoding an effector protein and a second DNA molecule operatively associated with the first DNA molecule and encoding a protein transduction domain of a human immunodeficiency virus TAT protein or derivatives or functional analogs thereof and its use in a method for delivering effector proteins into a target cell.
    Type: Grant
    Filed: September 13, 2000
    Date of Patent: November 26, 2002
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Alan Collmer, Steven V. Beer
  • Publication number: 20020116733
    Abstract: The present invention relates to a method of imparting pathogen resistance to plants. This involves applying a hypersensitive response elicitor polypeptide or protein in a non-infectious form to a plant seed under conditions where the polypeptide or protein contacts cells of the plant seed. The present invention is also directed to a pathogen resistance imparting plant seed. Alternatively, transgenic plant seeds containing a DNA molecule encoding a hypersensitive response elicitor polypeptide or protein can be planted in soil and a plant can be propagated from the planted seed under conditions effective to impart pathogen resistance to the plant.
    Type: Application
    Filed: January 19, 2001
    Publication date: August 22, 2002
    Inventors: Dewen Qiu, Zhong-Min Wei, Steven V. Beer
  • Publication number: 20020069434
    Abstract: The present invention relates to a chimeric gene that includes a first DNA molecule encoding a hypersensitive response elicitor protein or polypeptide, a promoter operably linked 5′ to the first DNA molecule to induce transcription of the first DNA molecule in response to activation of the promoter by an oomycete, and a 3′ regulatory region operably linked to the first DNA molecule. Also disclosed are an expression system and a host cell containing the chimeric gene. The present invention also relates to a transgenic plant resistant to disease resulting from oomycete infection, the transgenic plant including the chimeric gene, wherein the promoter induces transcription of the first DNA molecule in response to infection of the plant by an oomycete. Transgenic seeds and transgenic cultivars obtained from the transgenic plant are also disclosed. Additional aspects of the present invention include methods of making a recombinant plant cell and a transgenic plant.
    Type: Application
    Filed: January 26, 2001
    Publication date: June 6, 2002
    Inventors: Steven V. Beer, David W. Bauer
  • Patent number: 6333302
    Abstract: The present invention is directed to the use of a protein or polypeptide from Gram positive bacteria, such as Clavibacter michiganensis subsp. sepedonicus, which elicits a hypersensitive response in plants. This protein or polypeptide can used to impart disease resistance to plants, to enhance plant growth, and/or to control insects on plants. This can be achieved by applying the hypersensitive response elicitor protein or polypeptide in a non-infectious form to plants or plant seeds under conditions where the protein or polypeptide contacts the cells of the plant or the plant seed and is effective to impart disease resistance, to enhance plant growth, and/or to control insects on plants or plants grown from the plant seeds.
    Type: Grant
    Filed: August 19, 1998
    Date of Patent: December 25, 2001
    Assignees: Cornell Research Foundation, Inc., Eden Bioscience Corporation
    Inventors: Steven V. Beer, Jerry L. Butler
  • Patent number: 6277814
    Abstract: The present invention relates to a method of enhancing growth of plants. This involves applying a hypersensitive response elicitor polypeptide or protein in a non-infectious form to a plant or plant seed under conditions effective to enhance growth of the plant or plants produced from the plant seed. Alternatively, transgenic plants or transgenic plant seeds transformed with a DNA molecule encoding a hypersensitive response elicitor polypeptide or protein can be provided and the transgenic plants or plants resulting from the transgenic plant seeds are grown under conditions effective to enhance plant growth.
    Type: Grant
    Filed: January 26, 1998
    Date of Patent: August 21, 2001
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Dewen Qiu, Zhong-Min Wei, Steven V. Beer
  • Publication number: 20010011380
    Abstract: The present invention is directed to isolated fragments of an Erwinia hypersensitive response elicitor protein or polypeptide which fragments elicit a hypersensitive response in plants. Also disclosed are isolated DNA molecules which encode the Erwinia hypersensitive response eliciting fragment. Isolated fragments of hypersensitive response elicitor proteins or polypeptides, which elicit a hypersensitive response, and the isolated DNA molecules that encode them can used to impart disease resistance to plants, to enhance plant growth, and/or to control insects on plants. This can be achieved by applying the hypersensitive response eliciting fragments in a non-infectious form to plants or plant seeds under conditions effective to impart disease resistance, to enhance plant growth, and/or to control insects on plants or plants grown from the plant seeds.
    Type: Application
    Filed: May 28, 1998
    Publication date: August 2, 2001
    Inventors: RON J. LABY, ZHONG-MIN WEI, STEVEN V. BEER
  • Patent number: 6262018
    Abstract: The present invention is directed to an isolated protein or polypeptide which elicits a hypersensitive response in plants as well as an isolated DNA molecule which encodes the hypersensitive response eliciting protein or polypeptide. This isolated protein or polypeptide and the isolated DNA molecule can used to impart disease resistance to plants, to enhance plant growth, and/or to control insects on plants. This can be achieved by applying the hypersensitive response elicitor protein or polypeptide in a non-infectious form to plants or plant seeds under conditions effective to impart disease resistance, to enhance plant growth, and/or to control insects on plants or plants grown from the plant seeds.
    Type: Grant
    Filed: July 22, 1998
    Date of Patent: July 17, 2001
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Jihyun Francis Kim, Steven V. Beer
  • Patent number: 6235974
    Abstract: The present invention relates to a method of imparting pathogen resistance to plants. This involves applying a hypersensitive response elicitor polypeptide or protein in a non-infectious form to a plant seed under conditions where the polypeptide or protein contacts cells of the plant seed. The present invention is also directed to a pathogen resistance imparting plant seed. Alternatively, transgenic plant seeds containing a DNA molecule encoding a hypersensitive response elicitor polypeptide or protein can be planted in soil and a plant can be propagated from the planted seed under conditions effective to impart pathogen resistance to the plant.
    Type: Grant
    Filed: December 3, 1997
    Date of Patent: May 22, 2001
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Dewen Qiu, Zhong-Min Wei, Steven V. Beer
  • Patent number: 6228644
    Abstract: The present invention is directed to an isolated protein or polypeptide which elicits a hypersensitive response in plants as well as an isolated DNA molecule which encodes the hypersensitive response eliciting protein or polypeptide. This isolated protein or polypeptide and the isolated DNA molecule can used to impart disease resistance to plants, to enhance plant growth, and/or to control insects on plants. This can be achieved by applying the hypersensitive response elicitor protein or polypeptide in a non-infectious form to plants or plant seeds under conditions effective to impart disease resistance, to enhance plant growth, and/or to control insects on plants or plants grown from the plant seeds.
    Type: Grant
    Filed: July 22, 1998
    Date of Patent: May 8, 2001
    Assignee: Cornell Research Foundation, Inc.
    Inventors: Adam J. Bogdanove, Jihyun Francis Kim, Zhong-Min Wei, Steven V. Beer