Abstract: Embodiments of the invention relates to a temperature sensor and an analytical device comprising the same. The temperature sensor comprises a carrier (11) with a detection surface (12) on which temperature indicating agents (14) are present and, optionally, at which target components can collect and optionally bind to specific capture elements. An incident light beam (L1) is transmitted into the carrier and evanescent wave excitation is induced at the detection surface (12). The amount of light in the reflected light beam (L2) or an optical, e.g. luminescence response is then detected by a light detector (31). In one example, evanescent light is affected (absorbed, scattered) by temperature indicating agents and optionally target components and/or label particles at the binding surface (12) and will therefore be missing in a frustrated total internal reflected light beam (L2).

Abstract: According to the present invention, a process for treating cultured cells is provided, which comprises the steps of: a) providing planar, two-dimensional objects (“flakes”), wherein these objects comprise a material which, upon application of an extrinsic stimulus, is transferred from the planar state into a rolled state, b) providing cells on said flakes, and c) transferring the flakes from the planar state into a rolled state by application of said extrinsic stimulus.