Abstract: Systems, methods, and media for generating electronic books are provided herein. Methods may include obtaining digital source content, the digital source content being arranged in a native format, the native format determining how the digital source content is displayed on a user interface, and determining characteristics from the digital source content, the characteristics at least defining a layout of the digital source content in the native format; and rendering the determined content into an electronic book according to an electronic book standard, based upon the characteristics such that a generated format of the electronic book substantially corresponds to the native format of the digital source content.

Abstract: A variable grip blind rivet includes a tubular rivet body and a mandrel. The rivet body has a first shank, insertable into a hole in a workpiece, and a flange at a first end of the first shank for abutting the workpiece when so inserted. The mandrel has a head, for engaging a second end of the first shank, and a second shank adapted to extend through the axial bore of the rivet body. The head has an abutment portion for abutting the first end of the first shank, and the second shank has a first reduced diameter portion adapted to break when a predetermined tensile is loaded applied. At least one protrusion adjacent the abutment portion defines a recess for receiving the first end of the first shank during setting of the rivet.

Abstract: Methods of treating using adipose tissue using ultrasonic cavitation to dissociate the fat cells and blood vessels contained within adipose tissue and thereby obtain mesenchymal or stromal vascular fractions for use in human subjects are provided. These methods preferably do not include the use of any exogenous dissociating enzymes such as collagenase and result in increased numbers of the cells which constitute the mesenchymal or stromal vascular fractions (about 10-fold greater) than methods which use collagenase to isolate these cells.

Abstract: The present invention relates to compounds of formula (I) for stabilizing the tetrameric form of transthyretin, compounds for use in the treatment or prevention of amyloidosis, and agents and medicaments comprising such compounds. wherein X, Y, R1, R2, R3, R4, m, n, p, q, and the linker are as defined herein.

Abstract: Methods of treating using adipose tissue using ultrasonic cavitation to dissociate the fat cells and blood vessels contained within adipose tissue and thereby obtain mesenchymal or stromal vascular fractions for use in human subjects are provided. These methods preferably do not include the use of any exogenous dissociating enzymes such as collagenase and result in increased numbers of the cells which constitute the mesenchymal or stromal vascular fractions (about 10-fold greater) than methods which use collagenase to isolate these cells.

Abstract: A variable grip blind rivet includes a tubular rivet body and a mandrel. The rivet body has a first shank, insertable into a hole in a workpiece, and a flange at a first end of the first shank for abutting the workpiece when so inserted. The mandrel has a head, for engaging a second end of the first shank, and a second shank adapted to extend through the axial bore of the rivet body. The head has an abutment portion for abutting the first end of the first shank, and the second shank has a first reduced diameter portion adapted to break when a predetermined tensile is loaded applied. At least one protrusion adjacent the abutment portion defines a recess for receiving the first end of the first shank during setting of the rivet.

Abstract: Disclosed are compounds of Formula I: pharmaceutical compositions containing compounds of Formula I, and the use of compounds of Formula I to treat diseases and disorders including schizophrenia, paranoia, depression, manic-depressive illness and anxiety wherein W1-W5, X1-X4, Y, Z1-Z5, m, n, p, and R1-R6 in Formula I are defined in the specification.

Abstract: The present invention relates to compounds of formula (I) for stabilizing the tetrameric form of transthyretin, compounds for use in the treatment or prevention of amyloidosis, and agents and medicaments comprising such compounds. wherein X, Y, R1, R2, R3, R4, m, n, p, q, and the linker are as defined herein.

Abstract: A non-computer interface to a storage system includes a set top box (STB) or interface unit connected to a storage system for storing information to be accessed by a user. The storage system can be a database, such as a relational database having a plurality of tables, or a digital library system, for storing information to be accessed by the user. Also stored in the storage system are navigation information or rules for controlling a user's navigation of the database. A user interacts with the storage system through the STB, sending navigation commands to the storage system via the STB. The navigation commands available to a user are generated by combining the navigation rules with the user's access privileges. The user can send navigation commands via a remote controller which sends cursor control commands to the STB. Alternatively, the user can send navigation commands via a virtual reality interface.

Abstract: A customizable workflow is specified in a script that is associated with an object that is to be processed by the workflow. Both the object and the script can be stored in a content management system, with the object and script associated with one another by way of identifying the script in metadata stored in the system for the object. The script can be located by locating the object. The script can specify a sequence of a plurality of workflow processes that are performed over the life of the object.

Abstract: The present invention relates to novel compounds, compositions comprising said compounds, and uses thereof, said compounds having the formula: X is —CH2—, —O— or —NR9—; R is a carbocyclic or heterocyclic ring; R1 is a cysteine trap; R2a, R2a?, R2b, and R2b? are each independently hydrogen, C1–C4 alkyl, C1–C4 alkoxy, and mixtures thereof; or R2a? and R2b? can taken together to form a double bond; R9 is hydrogen or a unit having the formula -L2-R10; L is the same as defined herein above; R10 is hydrogen; substituted or unsubstituted C1–C6 linear; branched, or cyclic hydrocarbyl; substituted or unsubstituted aryl; substituted or unsubstituted C1–C9 heterocyclic; and substituted or unsubstituted heteroaryl.

Abstract: The present invention is directed to a method of treating the inflammation associated with acne, comprising applying a patch to an affected area of the skin, wherein said patch includes an efficacious amount of a cortisone. The patch of the present invention may be self adhesive or treated with a water activated adhesive and may be of one layer or multiple layers.

Abstract: The present invention relates to interleukin-1? converting enzyme inhibitors having the formula: R is a carbocyclic or heterocyclic ring; R1 is a cysteine trap; R2a, R2a?, R2b, and R2b? are each independently hydrogen, C1–C4 alkyl, C1–C4 alkoxy, and mixtures thereof; or R2a? and R2b? can taken together to form a double bond; L and L1 are linking groups having the formula: T is selected from the group consisting of: i) —NR6—; ii) —O—; iii) —NR6S(O)2—; iv) —S(O)2NR6—; and v) mixtures thereof; R6 is hydrogen, substituted or unsubstituted C1–C20 linear, branched, or cyclic alkyl, C6–C20 aryl, C7–C20 alkylenearyl, and mixtures thereof; the indices w, w1, and w2 are each independently 0 or 1; i) hydrogen; ii) C1–C4 linear, branched, and cyclic alkyl; iii) R3a and R3b or R4a, and R4b can be taken together to form a carbonyl unit; iv) two R3a or two R3b units from adjacent carbon atoms or two R4a or two R4b units from adjacent carbon atoms can be taken together to form a double bond; and v) mixtures thereof;

Abstract: Provided are a method, system, and program for defining asset classes in a digital library. At least one asset class is defined to include at least one attribute and attributes are defined for each asset class to have an attribute object type. The attribute object type is defined to indicate one of a plurality of different data structure formats that are searchable through separate application programs, wherein the attribute object types in one asset class are implemented in different data structure formats. A asset object instance is generated for each asset class and information is generated in the asset object instance on a file location of attribute objects providing the attributes for the generated asset object instance.

Abstract: The present invention relates to novel compounds, compositions comprising said compounds, and uses thereof, said compounds having the formula: wherein each X is independently selected from: i) —C(W)2—; ii) —C(O)—; iii) —NR2—; iv) —S—; v) —S(O)—; vi) —S(O)2—; vii) two units, one from each adjacent X unit, can be taken together to form a substituted or unsubstituted double bond having the formula —CW?CW—; wherein each W is hydrogen of a unit having the formula —(L2)j—R2, the index j is 0 or 1; R is a carbocyclic or heterocyclic aryl ring; R1 is a cysteine trap; each R2 is independently a suitable substituent; and L, L1, and L2 are linking units.

Abstract: Provided are a method, system, and program for defining asset classes in a digital library. At least one asset class is defined to include at least one attribute and attributes are defined for each asset class to have an attribute object type. The attribute object type is defined to indicate one of a plurality of different data structure formats that are searchable through separate application programs, wherein the attribute object types in one asset class are implemented in different data structure formats. A asset object instance is generated for each asset class and information is generated in the asset object instance on a file location of attribute objects providing the attributes for the generated asset object instance.

Abstract: A microencapsulated catalyst is prepared by dissolving or dispersing a catalyst in a first phase (for example an organic phase), dispersing the first phase in a second, continuous phase (for example an aqueous phase) to form an emulsion, reacting one or more microcapsule wall-forming materials at the interface between the dispersed first phase and the continuous second phase to form a microcapsule polymer shell encapsulating the dispersed first phase core and optionally recovering the microcapsules from the continuous phase. The catalyst is preferably a transition metal catalyst and the encapsulated catalyst may be used for conventional catalysed reactions. The encapsulated catalyst may recovered from the reaction medium and re-cycled.

Abstract: A customizable workflow is specified in a script that is associated with an object that is to be processed by the workflow. Both the object and the script can be stored in a content management system, with the object and script associated with one another by way of identifying the script in metadata stored in the system for the object. The script can be located by locating the object. The script can specify a sequence of a plurality of workflow processes that are performed over the life of the object.

Abstract: The present invention relates to novel compounds, compositions comprising said compounds, and uses thereof, said compounds having the formula: 1

Abstract: The present invention relates to novel compounds, compositions comprising said compounds, and uses thereof, said compounds having the formula: 1