Patents by Inventor Steven W. Elmore

Steven W. Elmore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apoptosis promoters
    Patent number: 7750004
    Abstract: Compounds which inhibit the activity of anti-apoptotic Mcl-1 protein, compositions containing the compounds and methods of treating diseases during which are expressed the Mcl-1 protein are disclosed.
    Type: Grant
    Filed: July 7, 2006
    Date of Patent: July 6, 2010
    Assignee: Abbott Laboratories
    Inventors: Michael D. Wendt, Hong Ding, Sheela A. Thomas, Steven W. Elmore, Wang Shen, Daniel A. Dickman, David Augeri
  • APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
    Publication number: 20100160322
    Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
    Type: Application
    Filed: December 4, 2009
    Publication date: June 24, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Milan Bruncko, Yujia Dai, Hong Ding, George A. Doherty, Steven W. Elmore, Lisa Hasvold, Laura Hexamer, Aaron Kunzer, Robert A. Mantei, William J. McClellan, Chang H. Park, Cheol-Min Park, Andrew M. Petros, Xiaohong Song, Andrew J. Souers, Gerard M. Sullivan, Zhi-Fu Tao, Gary T. Wang, Le Wang, Xilu Wang, Michael D. Wendt
  • BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE DISEASES
    Publication number: 20100152183
    Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 or Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which are expressed anti-apoptotic Bcl-2 protein.
    Type: Application
    Filed: December 4, 2009
    Publication date: June 17, 2010
    Applicant: ABBOTT LABORATORIES
    Inventors: Milan Bruncko, Hong Ding, George A. Doherty, Steven W. Elmore, Lisa Hasvold, Laura Hexamer, Aaron Kunzer, Robert A. Mantei, William J. McClellan, Chang H. Park, Cheol-Min Park, Andrew M. Petros, Xiaohong Song, Andrew J. Souers, Gerard M. Sullivan, Zhi-Fu Tao, Gary T. Wang, Le Wang, Xilu Wang, Michael D. Wendt
  • Apoptosis promoters
    Patent number: 7709467
    Abstract: Compounds which inhibit the activity of anti-apoptotic family protein members, compositions containing the compounds and methods of treating diseases during which occur expression one or more than one of an anti-apoptotic family protein member are disclosed.
    Type: Grant
    Filed: May 15, 2008
    Date of Patent: May 4, 2010
    Assignee: Abbott Laboratories
    Inventors: Milan Bruncko, Hong Ding, Steven W. Elmore, Aaron R. Kunzer, Christopher L. Lynch, William J. McClellan, Cheol Min Park, Xiahong Song, Xilu Wang
  • N-SULFONYLCARBOXIMIDAMIDE APOPTOSIS PROMOTERS
    Publication number: 20100035879
    Abstract: Compounds having the formula are apoptosis promoters. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: May 29, 2009
    Publication date: February 11, 2010
    Inventors: Steven W. Elmore, Milan Bruncko, Cheol-Min Park
  • N-sulfonylcarboximidamide apoptosis promoters
    Patent number: 7585858
    Abstract: Compounds having the formula are apoptosis promoters. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Grant
    Filed: May 26, 2005
    Date of Patent: September 8, 2009
    Assignee: Abbott Laboratories
    Inventors: Steven W. Elmore, Milan Bruncko, Cheol-Min Park
  • 7-NONSUBSTITUTED INDOLE MCL-1 INHIBITORS
    Publication number: 20090124616
    Abstract: Compounds which inhibit the activity of anti-apoptotic Mcl-1 protein, compositions containing the compounds, and methods of treating diseases involving overexpressed or unregulated Mcl-1 protein are disclosed.
    Type: Application
    Filed: April 16, 2008
    Publication date: May 14, 2009
    Applicant: Abbott Laboratories
    Inventors: Xiaohong Song, Hong Ding, Steven W. Elmore, Milan Bruncko, David J. Madar, Andrew J. Souers, Cheol-Min Park, Zhi-Fu Tao, Xilu Wang, Aaron R. Kunzer
  • 7-SUBSTITUTED INDOLE MCL-1 INHIBITORS
    Publication number: 20090054402
    Abstract: Compounds which inhibit the activity of anti-apoptotic Mcl-1 protein, compositions containing the compounds, and methods of treating diseases involving overexpressed or unregulated Mcl-1 protein are disclosed.
    Type: Application
    Filed: April 16, 2008
    Publication date: February 26, 2009
    Applicant: Abbott Laboratories
    Inventors: Xilu Wang, Xiaohong Song, Steven W. Elmore, Milan Bruncko, David J. Madar, Andrew J. Souers, Lisa A. Hasvold, Le Wang, Zhi-Fu Tao, Aaron R. Kunzer
  • APOPTOSIS PROMOTERS
    Publication number: 20080287419
    Abstract: Compounds which inhibit the activity of anti-apoptotic family protein members, compositions containing the compounds and methods of treating diseases during which occur expression one or more than one of an anti-apoptotic family protein member are disclosed.
    Type: Application
    Filed: May 15, 2008
    Publication date: November 20, 2008
    Applicant: Abbott Laboratories
    Inventors: Milan Bruncko, Hong Ding, Steven W. Elmore, Aaron R. Kunzer, Christopher L. Lynch, William J. McClellan, Cheol Min Park, Xiahong Song, Xilu Wang
  • N-sulfonylurea apoptosis promoters
    Patent number: 7449485
    Abstract: Compounds having the formula are apoptosis promoters. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Grant
    Filed: February 26, 2008
    Date of Patent: November 11, 2008
    Assignee: Abbott Laboratories Inc.
    Inventors: Steven W. Elmore, Cheol-Min Park, Xilu Wang
  • Apoptosis Promoters
    Publication number: 20080194691
    Abstract: Compounds of formula (I), in which B1 and X1 are together alkylene which is unsubstituted or substituted with ?O and having one CH2 moiety unreplaced or replaced with CH?CH, O, NH or N(alkyl), which inhibit the activity of antiapoptotic Bcl-2 family protein members, compositions containing the compounds and methods of treating diseases during which are expressed one or more than one of an anti-apoptotic family protein member are disclosed.
    Type: Application
    Filed: May 17, 2006
    Publication date: August 14, 2008
    Applicant: Abbott Laboratories
    Inventors: Steven W. Elmore, Christopher L. Lynch, Xilu Wang
  • Apoptosis promoters
    Patent number: 7390799
    Abstract: Compounds which inhibit the activity of anti-apoptotic family protein members, compositions containing the compounds and methods of treating diseases during which occur expression one or more than one of an anti-apoptotic family protein member are disclosed.
    Type: Grant
    Filed: May 12, 2006
    Date of Patent: June 24, 2008
    Assignee: Abbott Laboratories
    Inventors: Milan Bruncko, Hong Ding, Steven W. Elmore, Aaron R. Kunzer, Christopher L. Lynch, William J. McClellan, Cheol Min Park, Xiahong Song, Xilu Wang
  • N-SULFONYLUREA APOPTOSIS PROMOTERS
    Publication number: 20080146572
    Abstract: Compounds having the formula are apoptosis promoters. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: February 26, 2008
    Publication date: June 19, 2008
    Applicant: ABBOTT LABORATORIES
    Inventors: Steven W. Elmore, Cheol-Min Park, Xilu Wang
  • N-sulfonylurea apoptosis promoters
    Patent number: 7358251
    Abstract: Compounds having the formula are apoptosis promoters. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Grant
    Filed: November 29, 2005
    Date of Patent: April 15, 2008
    Assignee: Abbott Laboratories
    Inventors: Steven W. Elmore, Cheol-Min Park, Xilu Wang
  • N-sulfonylurea apoptosis promoters
    Patent number: 7030115
    Abstract: Compounds having the formula are apoptosis promoters. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Grant
    Filed: March 21, 2003
    Date of Patent: April 18, 2006
    Assignee: Abbott Laboratories
    Inventors: Steven W. Elmore, Cheol-Min Park, Xilu Wang
  • Glucocorticoid-selective anti-inflammatory agents
    Patent number: 6951942
    Abstract: Compounds having Formula I are useful for partially or fully antagonizing, repressing, agonizing, or modulating the glucocorticoid receptor and treating immune, autoimmune and inflammatory diseases in a mammal. Also disclosed are pharmaceutical compositions comprising compounds of Formula I and methods of inhibiting immune or autoimmune diseases in a mammal.
    Type: Grant
    Filed: July 23, 2002
    Date of Patent: October 4, 2005
    Assignees: Abbott Laboratories, Ligand Pharmaceuticals Incorporated
    Inventors: Michael J. Coghlan, James P. Edwards, Steven W. Elmore, Todd K. Jones, Michael E. Kort, Philip R. Kym, Jimmie L. Moore, John K. Pratt, Alan X. Wang
  • N-sulfonylurea apoptosis promoters
    Publication number: 20030236247
    Abstract: Compounds having the formula 1
    Type: Application
    Filed: March 21, 2003
    Publication date: December 25, 2003
    Inventors: Steven W. Elmore, Cheol-Min Park, Xilu Wang
  • Glucocortiocoid-selective antinflammatory agents
    Publication number: 20030073703
    Abstract: Compounds having Formula I 1
    Type: Application
    Filed: July 23, 2002
    Publication date: April 17, 2003
    Applicant: Abbott Laboratories and Ligand Pharmaceuticals Incorporated
    Inventors: Michael J. Coghlan, James P. Edwards, Steven W. Elmore, Todd K. Jones, Michael E. Kort, Philip R. Kym, Jimmie L. Moore, John K. Pratt, Alan X. Wang
  • Glucocortiocoid-selective antinflammatory agents
    Patent number: 6506766
    Abstract: Compounds having Formula I are useful for partially or fully antagonizing, repressing, agonizing, or modulating the glucocorticoid receptor and treating immune, autoimmune and inflammatory diseases in a mammal. Also disclosed are pharmaceutical compositions comprising compounds of Formula I and methods of inhibiting immune or autoimmune diseases in a mammal.
    Type: Grant
    Filed: July 5, 2000
    Date of Patent: January 14, 2003
    Assignees: Abbott Laboratories, Ligand Pharmaceuticals Incorporated
    Inventors: Michael J. Coghlan, James P. Edwards, Steven W. Elmore, Todd K. Jones, Michael E. Kort, Philip R. Kym, Jimmie L. Moore, John K. Pratt, Alan X. Wang
  • Quinoline and naphthyridine carboxylic acid antibacterials
    Publication number: 20020049223
    Abstract: Compounds having formula (I) 1
    Type: Application
    Filed: May 7, 2001
    Publication date: April 25, 2002
    Inventors: Steven W. Elmore, Curt S. Cooper, Colleen C. Schultz, Douglas K. Hutchinson, Pamela L. Donner, Brian E. Green, David D. Anderson, Qinghua Xie, Jurgen Dinges, Linda M. Lynch, John K. Pratt