Abstract: The over-the-wire interlock attachment/detachment mechanism includes a cylindrical lock receiving section of a small diameter attached to an implantable medical device such as a blood clot filter, a stent, or a septal occluder. This cylindrical lock receiving section has a plurality of spaced, curved cutouts to receive both the guide fingers and contoured locking fingers formed on a cylindrical locking section. The locking fingers are angled outwardly from the cylindrical body of the cylindrical locking section, and are moved inwardly into engagement with the curved cutouts of the cylindrical lock receiving section by a sheath which slides over the cylindrical locking section or other suitable operator.

Abstract: Devices and techniques for modifying and maintaining a configuration of an occlusion device for the closure of physical anomalies, such as an atrial septal defect, a patent foramen ovale (PFO), and other septal and vascular defects are described. The devices and techniques relate particularly to, but are not limited to, modifying and maintaining a configuration of a PFO occluder made from a polymer tube. The proximal portion of a catch member may be provided with one or more protrusions, or arms, or bump or other raised element for securing the occluder in a partial or fully deployed configuration, either temporarily or permanently.

Abstract: The invention generally relates to an intravascular catheter that includes a proximal hub and a distal elongated tubular member. In one embodiment, the hub is designed to mitigate the introduction of air into a patient's vasculature during the delivery of a second device through the catheter into the patient's body.

Abstract: Devices, delivery systems and delivery techniques for an occlusion device for the closure of physical anomalies, such as an atrial septal defect, a patent foramen ovale (PFO), and other septal and vascular defects are described. The devices, delivery systems and delivery techniques relate particularly to, but are not limited to, a patent foramen ovale (PFO) occluder made from a polymer tube. In certain embodiments, the occluder includes a catch system that holds the occluder in the deployed, expanded profile. The catch system includes a locking funnel cap. In some embodiments, the locking funnel cap forces the proximal ends of the occluder in a radially inward position to lock the catch member in place and prevent the occluder from moving from its deployed configuration.

Abstract: Devices and techniques for modifying and maintaining a configuration of an occlusion device for the closure of physical anomalies, such as an atrial septal defect, a patent foramen ovale (PFO), and other septal and vascular defects are described. The devices and techniques relate particularly to, but are not limited to, modifying and maintaining a configuration of a PFO occluder made from a polymer tube. The proximal portion of a catch member may be provided with one or more protrusions, or arms, or bump or other raised element for securing the occluder in a partial or fully deployed configuration, either temporarily or permanently.

Abstract: The over-the-wire interlock attachment/detachment mechanism includes a cylindrical lock receiving section of a small diameter attached to an implantable medical device such as a blood clot filter, a stent, or a septal occluder. This cylindrical lock receiving section has a plurality of spaced, curved cutouts to receive both the guide fingers and contoured locking fingers formed on a cylindrical locking section. The locking fingers are angled outwardly from the cylindrical body of the cylindrical locking section, and are moved inwardly into engagement with the curved cutouts of the cylindrical lock receiving section by a sheath which slides over the cylindrical locking section or other suitable operator.

Abstract: A coupling system is disposed at the distal end of an interventional delivery system for coupling to an implant. The coupling device has a first and second prong connected at one end. The other end of the prongs open or close to release or trap an object, e.g., a bead tethered from an implant. A slot at the distal end of the coupling device allows extra degrees of flexibility for the coupling device.

Abstract: A coupling system is disposed at the distal end of an interventional delivery system for coupling to an implant. The coupling device has a first and second prong connected at one end. The other end of the prongs open or close to release or trap an object, e.g., a bead tethered from an implant. A slot at the distal end of the coupling device allows extra degrees of flexibility for the coupling device.

Abstract: The over-the-wire interlock attachment/detachment mechanism includes a cylindrical lock receiving section of a small diameter attached to an implantable medical device such as a blood clot filter, a stent, or a septal occluder. This cylindrical lock receiving section has a plurality of spaced, curved cutouts to receive both the guide fingers and contoured locking fingers formed on a cylindrical locking section. The locking fingers are angled outwardly from the cylindrical body of the cylindrical locking section, and are moved inwardly into engagement with the curved cutouts of the cylindrical lock receiving section by a sheath which slides over the cylindrical locking section or other suitable operator.

Abstract: Disclosed herein are devices and methods for occluding intracardiac defects, for example, a patent foramen ovale (PFO). The devices according to the invention have various features that enhance the flexibility of the device and improve the device's ability to conform to the location of the intracardiac defect. In particular, intracardiac occluders with curved arms are disclosed.

Abstract: The invention generally relates to an intravascular catheter that includes a proximal hub and a distal elongated tubular member. In one embodiment, the hub is designed to mitigate the introduction of air into a patient's vasculature during the delivery of a second device through the catheter into the patient's body.

Abstract: The invention generally relates to an intravascular catheter that includes a proximal hub and a distal elongated tubular member. In one embodiment, the hub is designed to mitigate the introduction of air into a patient's vasculature during the delivery of a second device through the catheter into the patient's body.

Abstract: Devices, delivery systems and techniques for an occlusion device for the closure of physical anomalies, such as an atrial septal defect, a patent foramen ovale (PFO), and other septal and vascular defects are described. The devices, delivery systems and techniques relate to, but are not limited to, a patent foramen ovale (PFO) occluder made from a substantially cylindrical form. An occluder having a distal side and a proximal side, with a catch system for securing the deployed configuration, is introduced into the treatment site by a delivery sheath. In one aspect, the occluder has an adjustable length center joint that allows the device to fit a particular septal defect. In some embodiments, the occluder includes a catch member that holds the occluder in the deployed, expanded profile configuration. In one aspect, the catch member also has an adjustable length.

Abstract: An implant for occluding a septal defect, such as a patent foramen ovale (PFO), and methods of delivering the implant are described. The implant includes a scaffold, at least one channel, and an injection port in fluid communication with the channels for inflating the scaffold.

Abstract: A magnetic attachment device is provided for use in a transcatheter delivery system. The system may be useful for delivering, repositioning, and removal of an implant, such as a septal occluder, in or out of a patient.

Abstract: A coupling system is disposed at the distal end of an interventional delivery system for coupling to an implant. The coupling device has a first and second prong connected at one end. The other end of the prongs open or close to release or trap an object, e.g., a bead tethered from an implant. A slot at the distal end of the coupling device allows extra degrees of flexibility for the coupling device.

Abstract: A coupling system is disposed at the distal end of an interventional delivery system for coupling to an implant. The coupling device has a first and second prong connected at one end. The other end of the prongs open or close to release or trap an object, e.g., a bead tethered from an implant. A slot at the distal end of the coupling device allows extra degrees of flexibility for the coupling device.

Abstract: The present invention provides methods and devices for closing two overlapping layers of tissue in a mammalian heart, for example a patent foramen ovale (PFO). The closure devices may take a number of different forms and may be retrievable. In some embodiments, the closure devices may be delivered with a catheter capable of puncturing mammalian tissue.

Abstract: The over-the-wire interlock attachment/detachment mechanism includes a cylindrical lock receiving section of a small diameter attached to an implantable medical device such as a blood clot filter, a stent, or a septal occluder. This cylindrical lock receiving section has a plurality of spaced, curved cutouts to receive both the guide fingers and contoured locking fingers formed on a cylindrical locking section. The locking fingers are angled outwardly from the cylindrical body of the cylindrical locking section, and are moved inwardly into engagement with the curved cutouts of the cylindrical lock receiving section by a sheath which slides over the cylindrical locking section or other suitable operator.

Abstract: A medical device comprising a flexible, elongated member sized and shaped to fit within a vessel and defining a first lumen. A distal end of the flexible, elongated member including a port for connection to a vacuum source. A wire is slideably positionable within the first lumen and is movable between a first position and a second position. A cutting instrument is attached to a distal end of the wire and is retracted within the distal end of the lumen when the wire is at the first position and extending outside the distal end of the lumen when the wire is at the second position.