Patents by Inventor Steven W. Paugh

Steven W. Paugh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for overcoming glucocorticoid resistance and for determining glucocorticoid resistance potential in cancer
    Patent number: 11946053
    Abstract: The invention provides methods for overcoming glucocorticoid resistance of cancers by inhibition of CASP1. Also disclosed are diagnostic methods for determining glucocorticoid resistance potential by measuring expression level or promoter methylation status of CASP1 gene and/or NLRP3 gene.
    Type: Grant
    Filed: October 2, 2019
    Date of Patent: April 2, 2024
    Assignee: St. Jude Children's Research Hospital, Inc.
    Inventors: Steven W. Paugh, William E. Evans, Erik Bonten
  • METHODS FOR OVERCOMING GLUCOCORTICOID RESISTANCE AND FOR DETERMINING GLUCOCORTICOID RESISTANCE POTENTIAL IN CANCER
    Publication number: 20200102565
    Abstract: The invention provides methods for overcoming glucocorticoid resistance of cancers by inhibition of CASP1. Also disclosed are diagnostic methods for determining glucocorticoid resistance potential by measuring expression level or promoter methylation status of CASP1 gene and/or NLRP3 gene.
    Type: Application
    Filed: October 2, 2019
    Publication date: April 2, 2020
    Applicant: St. Jude Children's Research Hospital, Inc.
    Inventors: Steven W. Paugh, William E. Evans, Erik Bonten
  • Methods for overcoming glucocorticoid resistance and for determining glucocorticoid resistance potential in cancer
    Patent number: 10457946
    Abstract: The invention provides methods for overcoming glucocorticoid resistance of cancers by inhibition of CASP1. Also disclosed are diagnostic methods for determining glucocorticoid resistance potential by measuring expression level or promoter methylation status of CASP1 gene and/or NLRP3 gene.
    Type: Grant
    Filed: September 16, 2014
    Date of Patent: October 29, 2019
    Assignee: ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC.
    Inventors: Steven W. Paugh, William E. Evans, Erik Bonten
  • METHODS FOR OVERCOMING GLUCOCORTICOID RESISTANCE AND FOR DETERMINING GLUCOCORTICOID RESISTANCE POTENTIAL IN CANCER
    Publication number: 20160230173
    Abstract: The invention provides methods for overcoming glucocorticoid resistance of cancers by inhibition of CASP1. Also disclosed are diagnostic methods for determining glucocorticoid resistance potential by measuring expression level or promoter methylation status of CASP1 gene and/or NLRP3 gene.
    Type: Application
    Filed: September 16, 2014
    Publication date: August 11, 2016
    Applicant: St. Jude Children's Research Hospital, Inc.
    Inventors: Steven W. Paugh, William E. Evans, Erik Bonten