Patents by Inventor Steven Wagner

Steven Wagner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted pyridinones as bromodomain inhibitors
    Patent number: 10710992
    Abstract: The present disclosure relates to substituted pyridinones, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: July 14, 2020
    Assignee: Zenith Epigenetics Ltd.
    Inventors: May Xiaowu Jiang, Bruce Francis Molino, Shuang Liu, Ruifang Wang, Bryan Cordell Duffy, John Frederick Quinn, Gregory Steven Wagner
  • NOVEL BICYCLIC BROMODOMAIN INHIBITORS
    Publication number: 20190358237
    Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.
    Type: Application
    Filed: June 13, 2019
    Publication date: November 28, 2019
    Inventors: John Frederick Quinn, Bryan Cordell Duffy, Shuang LIU, Ruifang Wang, May Xiaowu Jiang, Gregory Scott Martin, Gregory Steven Wagner, Peter Ronald Young
  • Bicyclic bromodomain inhibitors
    Patent number: 10363257
    Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: July 30, 2019
    Assignee: Zenith Epigenetics Ltd.
    Inventors: John Frederick Quinn, Bryan Cordell Duffy, Shuang Liu, Ruifang Wang, May Xiaowu Jiang, Gregory Scott Martin, Gregory Steven Wagner, Peter Roland Young
  • NOVEL SUBSTITUTED BICYCLIC COMPOUNDS AS BROMODOMAIN INHIBITORS
    Publication number: 20190216782
    Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.
    Type: Application
    Filed: January 18, 2019
    Publication date: July 18, 2019
    Inventors: Shuang Liu, John Frederick Quinn, Bryan Cordell Duffy, Ruifang Wang, May Xiaowu Jiang, Gregory Scott Martin, He Zhao, Michael Ellis, Gregory Steven Wagner, Peter Ronald Young
  • Substituted bicyclic compounds as bromodomain inhibitors
    Patent number: 10226451
    Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: March 12, 2019
    Assignee: Zenith Epigenetics Ltd.
    Inventors: Shuang Liu, John Frederick Quinn, Bryan Cordell Duffy, Ruifang Wang, May Xiaowu Jiang, Gregory Scott Martin, He Zhao, Michael Ellis, Gregory Steven Wagner, Peter Ronald Young
  • Substituted pyridines as bromodomain inhibitors
    Patent number: 10179125
    Abstract: The disclosure relates to substituted pyridines, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: January 15, 2019
    Assignee: Zenith Epigenetics Ltd.
    Inventors: May Xiaowu Jiang, Bruce Francis Molino, Shuang Liu, Ruifang Wang, Bryan Cordell Duffy, John Frederick Quinn, Gregory Steven Wagner
  • Substituted bicyclic compounds as bromodomain inhibitors
    Patent number: 10166215
    Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.
    Type: Grant
    Filed: April 20, 2017
    Date of Patent: January 1, 2019
    Assignee: Zenith Epigenetics Ltd.
    Inventors: Shuang Liu, John Frederick Quinn, Bryan Cordell Duffy, Ruifang Wang, May Xiaowu Jiang, Gregory Scott Martin, He Zhao, Michael Ellis, Gregory Steven Wagner, Peter Ronald Young
  • Bicyclic bromodomain inhibitors
    Patent number: 10010556
    Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.
    Type: Grant
    Filed: April 12, 2017
    Date of Patent: July 3, 2018
    Assignee: Zenith Epigenetics Ltd.
    Inventors: John Frederick Quinn, Bryan Cordell Duffy, Shuang Liu, Ruifang Wang, May Xiaowu Jiang, Gregory Scott Martin, Gregory Steven Wagner, Peter Ronald Young
  • Substituted bicyclic compounds as bromodomain inhibitors
    Patent number: 9999616
    Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.
    Type: Grant
    Filed: April 20, 2017
    Date of Patent: June 19, 2018
    Assignee: Zenith Epigenetics Ltd.
    Inventors: Shuang Liu, John Frederick Quinn, Bryan Cordell Duffy, Ruifang Wang, May Xiaowu Jiang, Gregory Scott Martin, He Zhao, Michael Ellis, Gregory Steven Wagner, Peter Ronald Young
  • NOVEL BICYCLIC BROMODOMAIN INHIBITORS
    Publication number: 20180161337
    Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.
    Type: Application
    Filed: January 19, 2018
    Publication date: June 14, 2018
    Inventors: John Frederick QUINN, Bryan Cordell DUFFY, Shuang LIU, Ruifang WANG, May Xiaowu JIANG, Gregory Scott MARTIN, Gregory Steven WAGNER, Peter Ronald YOUNG
  • SUBSTITUTED PYRIDINES AS BROMODOMAiN INHIBITORS
    Publication number: 20170360765
    Abstract: The disclosure relates to substituted pyridines, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.
    Type: Application
    Filed: December 1, 2015
    Publication date: December 21, 2017
    Inventors: May Xiaowu Jiang, Bruce Francis Molino, Shuang Liu, Ruifang Wang, Bryan Cordell Duffy, John Frederick Quinn, Gregory Steven Wagner
  • Online analytic processing cube with time stamping
    Patent number: 9830366
    Abstract: In one example embodiment, a system and method are shown for receiving data that include a time stamp. The system and method also include building an Online Analytical Processing (OLAP) cube that includes a dimension, the dimension acting as a schema for the data that include the time stamp. The system and method may also include populating the OLAP cube with an object, the object including the data and the time stamp as at least one attribute. The system and method may also include storing the OLAP cube.
    Type: Grant
    Filed: March 23, 2009
    Date of Patent: November 28, 2017
    Assignee: Thomson Reuters Global Resources
    Inventor: Steven Wagner
  • SUBSTITUTED PYRIDINONES AS BROMODOMAIN INHIBITORS
    Publication number: 20170320866
    Abstract: The present disclosure relates to substituted pyridinones, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.
    Type: Application
    Filed: December 1, 2015
    Publication date: November 9, 2017
    Inventors: May Xiaowu Jiang, Bruce Francis Molino, Shuang Liu, Ruifang Wang, Bryan Cordell Duffy, John Frederick Quinn, Gregory Steven Wagner
  • Biaryl derivatives as bromodomain inhibitors
    Patent number: 9765039
    Abstract: The present disclosure relates to compounds, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.
    Type: Grant
    Filed: November 20, 2013
    Date of Patent: September 19, 2017
    Assignee: Zenith Epigenetics Ltd.
    Inventors: David John Fairfax, Gregory Scott Martin, John Frederick Quinn, Bryan Cordell Duffy, Gregory Steven Wagner, Peter Ronald Young
  • NOVEL BICYCLIC BROMODOMAIN INHIBITORS
    Publication number: 20170216301
    Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.
    Type: Application
    Filed: April 12, 2017
    Publication date: August 3, 2017
    Inventors: John Frederick QUINN, Bryan Cordell DUFFY, Shuang LIU, Ruifang WANG, May Xiaowu JIANG, Gregory Scott MARTIN, Gregory Steven WAGNER, Peter Ronald YOUNG
  • NOVEL SUBSTITUTED BICYCLIC COMPOUNDS AS BROMODOMAIN INHIBITORS
    Publication number: 20170216257
    Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.
    Type: Application
    Filed: April 20, 2017
    Publication date: August 3, 2017
    Inventors: Shuang Liu, John Frederick QUINN, Bryan Cordell DUFFY, Ruifang WANG, May Xiaowu JIANG, Gregory Scott MARTIN, He ZHAO, Michael ELLIS, Gregory Steven WAGNER, Peter Ronald YOUNG
  • NOVEL SUBSTITUTED BICYCLIC COMPOUNDS AS BROMODOMAIN INHIBITORS
    Publication number: 20170182029
    Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.
    Type: Application
    Filed: March 15, 2017
    Publication date: June 29, 2017
    Inventors: Shuang LIU, John Frederick QUINN, Bryan Cordell DUFFY, Ruifang WANG, May Xiaowu JIANG, Gregory Scott MARTIN, He ZHAO, Michael ELLIS, Gregory Steven WAGNER, Peter Ronald YOUNG
  • Substituted bicyclic compounds as bromodomain inhibitors
    Patent number: 9662311
    Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.
    Type: Grant
    Filed: June 20, 2014
    Date of Patent: May 30, 2017
    Assignee: Zenith Epigenetics Ltd.
    Inventors: Shuang Liu, John Frederick Quinn, Bryan Cordell Duffy, Ruifang Wang, May Xiaowu Jiang, Gregory Scott Martin, He Zhao, Michael Ellis, Gregory Steven Wagner, Peter Ronald Young
  • Bicyclic bromodomain inhibitors
    Patent number: 9663520
    Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: May 30, 2017
    Assignee: Zenith Epigenetics Ltd.
    Inventors: John Frederick Quinn, Bryan Cordell Duffy, Shuang Liu, Ruifang Wang, May Xiaowu Jiang, Gregory Scott Martin, Gregory Steven Wagner, Peter Ronald Young
  • Substituted bicyclic compounds as bromodomain inhibitors
    Patent number: 9636328
    Abstract: The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.
    Type: Grant
    Filed: June 20, 2014
    Date of Patent: May 2, 2017
    Assignee: Zenith Epigenetics Ltd.
    Inventors: Shuang Liu, John Frederick Quinn, Bryan Cordell Duffy, Ruifang Wang, May Xiaowu Jiang, Gregory Scott Martin, He Zhao, Michael Ellis, Gregory Steven Wagner, Peter Ronald Young