Abstract: An energy generation device Including: a surface for supporting movement of a work material, and an energy converter. The surface is operable to induce movement of the work material relative to the surface. The energy converter is arranged to generate electrical energy based on the induced movement of the work material relative to the surface.

Abstract: The present invention provides a vented individual negative pressure enclosure system for extracting potentially contaminated air from an individual. The system includes an adjustable assemblable and disassemblable frame structure configured to surround a bed, chair, or toilet. A vapor-impermeable sheet extends over the frame structure. An air purification system communicates with a plurality of extraction vents positioned on or in the frame structure. The air purification system may be a water-filtration-based air purification system including a particle growth tube for increasing the size of aerosol droplets to facilitate capture. The air purification system includes a pump and HEPA filter and, optionally, a UV sterilizer.

Abstract: A helmet comprising first and second parts and a connector connecting the first and second parts of the helmet, the connector comprising: a first plate; a first anchor point on one side of the first plate, configured to be connected to the first part; a second plate located on an opposite side of the first plate from the first anchor point; a second anchor point on an opposite side of the second plate from the first plate, configured to be connected to the second part; a low friction interface provided between opposing surfaces of the first and second plates; and a cuff of deformable material provided around the first and second plates, and configured to at least partially cover the side of the first plate on which the first anchor point is located and to at least partially cover the side of the second plate on which the second anchor point is located.

Abstract: The present disclosure relates to systems and methods for testing functional vision of a subject. The systems and methods utilize a plurality of obstacle courses, a plurality of contrast levels of the obstacle courses, a plurality of illumination levels, video-recording, and a robust scoring algorithm to assess the mobility of the subject.

Abstract: The present invention provides a wireless rechargeable and portable anti-microbial respirator. The respirator includes a face-piece with an air inlet and an air outlet; a first belt and a second belt, the first belt is connected to ends of the face-piece, and the second belt is configured to wrap around the waist of a user; a flexible outlet tube, where the first end of the flexible outlet tube is connected to the air outlet of the face-piece; a flexible intake tube, where the first end of the flexible intake tube is connected to the air inlet of the face-piece; and a filtration system fixed onto the second belt. The key features of the respirator in the present invention include highly antibacterial and antiviral, long duration, reusable, self-cleaning and self-disinfecting, lightweight and portable, wireless power transfer, and great airflow and comfortable breathing.

Abstract: A fog-based self-powered system for collecting atmospheric water and generating electricity is presented. The system includes a mesh-based fog harvester for accumulating water droplets from atmospheric moisture. A droplet distributor receives accumulated water droplets from the mesh-based fog harvester. A droplet electrical generator harvests energy from the water droplets accumulated in the droplet distributor. The droplet electrical generator includes an electret surface for receiving the water droplets from the droplet distributor and at least two electrodes. A water reservoir receives water droplets from the droplet electrical generator.

Abstract: The present invention relates generally to chromosome maintenance and cell viability, and more specifically, to the identification of kinases the inhibition of which blocks telomere elongation. In one aspect, the present invention provides methods for treating cancer. The methods generally comprise the administration of agents that interfere with the lengthening of telomeres in cancer. In a specific embodiment, a method of treating cancer in a subject by interfering with lengthening of telomeres in cancer cells comprises administering to the cells an effective amount of an inhibitor of casein kinase 1 (CK1), wherein the administration of the inhibitor leads to progressive telomere shortening in the cancer cell, thereby treating cancer in the subject. In another embodiment, the method can further comprise administering to the cells an effective amount of an inhibitor of bromodomain-containing protein 4 (BRD4) and/or an inhibitor of the MEK/ERK pathway.

Abstract: An elastic terminal ferrule includes an annular body, a limit structure formed on the annular body, and a mating limit structure formed on the annular body for mating with the limit structure. When the annular body is in a natural state without radial expansion, the limit structure and the mating limit structure are spaced apart from each other in a circumferential direction. When the outer diameter of the annular body is expanded to a predetermined value, the limit structure and the mating limit structure abut against each other in the circumferential direction to prevent further radial expansion of the elastic terminal ferrule.

Abstract: According to an exemplary embodiment of the present disclosure, a cosmetic arrangement can be provided, which can include a first structure that can enclose a cosmetic active ingredient(s), a second structure that can enclose a solvent solution, a third structure(s) that can separate the solvent solution from the cosmetic active ingredient(s), a medium that can be configured to absorb a mixture of the cosmetic active ingredient(s) and solvent solution, and an indicator structure that can be configured to indicate whether the cosmetic active ingredient(s) and the solvent solution have come in contact with one another. Upon an application of a particular amount of pressure on a portion(s) of the arrangement, the cosmetic active ingredient(s) and the solvent solution can be caused to come into direct contact with one another.

Abstract: A helmet comprising first and second parts and a connector connecting the first and second parts of the helmet, the connector comprising: a first plate; a first anchor point on one side of the first plate, configured to be connected to the first part; a second plate located on an opposite side of the first plate from the first anchor point; a second anchor point on an opposite side of the second plate from the first plate, configured to be connected to the second part; a low friction interface provided between opposing surfaces of the first and second plates; and a cuff of deformable material provided around the first and second plates, and configured to at least partially cover the side of the first plate on which the first anchor point is located and to at least partially cover the side of the second plate on which the second anchor point is located.

Abstract: The present invention provides methods of treating patients with long acting injectable paliperidone palmitate formulations. The disclosure includes methods for mitigating at least one adverse change in blood lipid levels of a patient in need thereof who has been treated with a paliperidone palmitate extended-release injectable suspension at either one-month intervals (PP1M) or three-month intervals (PP3M), comprising transitioning the patient to a paliperidone palmitate extended-release injectable suspension having a six month dosing interval (PP6M).

Abstract: The present invention provides a wireless rechargeable and portable anti-microbial respirator. The respirator includes a face-piece with an air inlet and an air outlet; a first belt and a second belt, the first belt is connected to ends of the face-piece, and the second belt is configured to wrap around the waist of a user; a flexible outlet tube, where the first end of the flexible outlet tube is connected to the air outlet of the face-piece; a flexible intake tube, where the first end of the flexible intake tube is connected to the air inlet of the face-piece; and a filtration system fixed onto the second belt. The key features of the respirator in the present invention include highly antibacterial and antiviral, long duration, reusable, self-cleaning and self-disinfecting, lightweight and portable, wireless power transfer, and great airflow and comfortable breathing.

Abstract: The present invention provides a vented individual negative pressure enclosure system for extracting potentially contaminated air from an individual. The system includes an adjustable assemblable and disassemblable frame structure configured to surround a bed, chair, or toilet. A vapor-impermeable sheet extends over the frame structure. An air purification system communicates with a plurality of extraction vents positioned on or in the frame structure. The air purification system may be a water-filtration-based air purification system including a particle growth tube for increasing the size of aerosol droplets to facilitate capture. The air purification system includes a pump and HEPA filter and, optionally, a UV sterilizer.

Abstract: An energy generation device Including: a surface for supporting movement of a work material, and an energy converter. The surface is operable to induce movement of the work material relative to the surface. The energy converter is arranged to generate electrical energy based on the induced movement of the work material relative to the surface.

Abstract: A fog-based self-powered system for collecting atmospheric water and generating electricity is presented. The system includes a mesh-based fog harvester for accumulating water droplets from atmospheric moisture. A droplet distributor receives accumulated water droplets from the mesh-based fog harvester. A droplet electrical generator harvests energy from the water droplets accumulated in the droplet distributor. The droplet electrical generator includes an electret surface for receiving the water droplets from the droplet distributor and at least two electrodes. A water reservoir receives water droplets from the droplet electrical generator.

Abstract: According to an exemplary embodiment of the present disclosure, a cosmetic arrangement can be provided, which can include a first structure that can enclose a cosmetic active ingredient(s), a second structure that can enclose a solvent solution, a third structure(s) that can separate the solvent solution from the cosmetic active ingredient(s), a medium that can be configured to absorb a mixture of the cosmetic active ingredient(s) and solvent solution, and an indicator structure that can be configured to indicate whether the cosmetic active ingredient(s) and the solvent solution have come in contact with one another. Upon an application of a particular amount of pressure on a portion(s) of the arrangement, the cosmetic active ingredient(s) and the solvent solution can be caused to come into direct contact with one another.

Abstract: A connector for connecting first and second parts of an apparatus, comprising a first plate; a first anchor point on one side of the first plate, configured to be connected to the first part; a second plate located on an opposite side of the first plate from the first anchor point; a second anchor point on an opposite side of the second plate from the first plate, configured to be connected to the second part; a low friction interface provided between opposing surfaces of the first and second plates; and a cuff of deformable material provided around the first and second plates, and configured to at least partially cover the side of the first plate on which the first anchor point is located and to at least partially cover the side of the second plate on which the second anchor point is located.

Abstract: A compressor includes an inlet and the inlet includes a flange and an impeller eye. The flange is connected to a suction line that transfers a refrigerant into the compressor via the impeller eye. The refrigerant flows into the compressor with an amount of swirl and a pressure loss. The suction line includes a geometry that includes a constantly decreasing cross-sectional area in a direction towards the compressor. The geometry of the suction line is configured to reduce the amount of swirl and the pressure loss.

Abstract: Aspects discussed herein are directed to ergonomic pointing device systems. In one example, a pointing device system includes an elongate base member, a sleeve disposed to fit over at least a portion of the elongate base member, the sleeve configured to rotate about the elongate base member in a first direction and slide about the elongate base member in a second direction substantially orthogonal to the first direction, where the sleeve includes a pattern on a surface thereof, and a sensor disposed within the elongate base member and positioned to detect at least one of a rotational movement of the sleeve relative to the sensor and an axial movement of the sleeve relative to the sensor based at least in part on a variation of the pattern within a field of view of the sensor.

Abstract: According to an exemplary embodiment of the present disclosure, a cosmetic arrangement can be provided, which can include a first structure that can enclose a cosmetic active ingredient(s), a second structure that can enclose a solvent solution, a third structure(s) that can separate the solvent solution from the cosmetic active ingredient(s), a medium that can be configured to absorb a mixture of the cosmetic active ingredient(s) and solvent solution, and an indicator structure that can be configured to indicate whether the cosmetic active ingredient(s) and the solvent solution have come in contact with one another. Upon an application of a particular amount of pressure on a portion(s) of the arrangement, the cosmetic active ingredient(s) and the solvent solution can be caused to come into direct contact with one another.