Patents by Inventor Steven Wesolowski

Steven Wesolowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HALO-SUBSTITUTED PIPERIDINES AS OREXIN RECEPTOR MODULATORS
    Publication number: 20220380359
    Abstract: The present application relates to certain halo-substituted piperidine compounds, pharmaceutical compositions containing them, and methods of using them, including methods for treating substance addiction, panic disorder, anxiety, post-traumatic stress disorder, pain, depression, seasonal affective disorder, an eating disorder, or hypertension.
    Type: Application
    Filed: July 20, 2022
    Publication date: December 1, 2022
    Inventors: Theodore M. Kamenecka, Jörg Holenz, Steven Wesolowski, Yuanjun He, Roland Bürli
  • Halo-substituted piperidines as orexin receptor modulators
    Patent number: 11434236
    Abstract: The present application relates to certain halo-substituted piperidine compounds, pharmaceutical compositions containing them, and methods of using them, including methods for treating substance addiction, panic disorder, anxiety, post-traumatic stress disorder, pain, depression, seasonal affective disorder, an eating disorder, or hypertension.
    Type: Grant
    Filed: December 9, 2020
    Date of Patent: September 6, 2022
    Assignees: ASTRAZENECA AB, EOLAS THERAPEUTICS, INC.
    Inventors: Theodore M. Kamenecka, Jörg Holenz, Steven Wesolowski, Yuanjun He, Roland Bürli
  • HALO-SUBSTITUTED PIPERIDINES AS OREXIN RECEPTOR MODULATORS
    Publication number: 20210214348
    Abstract: The present application relates to certain halo-substituted piperidine compounds, pharmaceutical compositions containing them, and methods of using them, including methods for treating substance addiction, panic disorder, anxiety, post-traumatic stress disorder, pain, depression, seasonal affective disorder, an eating disorder, or hypertension.
    Type: Application
    Filed: December 9, 2020
    Publication date: July 15, 2021
    Inventors: Theodore M. Kamenecka, Jörg Holenz, Steven Wesolowski, Yuanjun He, Roland Bürli
  • Halo-substituted piperidines as orexin receptor modulators
    Patent number: 10894789
    Abstract: The present application relates to certain halo-substituted piperidine compounds, pharmaceutical compositions containing them, and methods of using them, including methods for treating substance addiction, panic disorder, anxiety, post-traumatic stress disorder, pain, depression, seasonal affective disorder, an eating disorder, or hypertension.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: January 19, 2021
    Assignees: ASTRAZENECA AB, EOLAS THERAPEUTICS, INC.
    Inventors: Theodore M. Kamenecka, Jörg Holenz, Steven Wesolowski, Yuanjun He, Roland Bürli
  • HALO-SUBSTITUTED PIPERIDINES AS OREXIN RECEPTOR MODULATORS
    Publication number: 20190135800
    Abstract: The present application relates to certain halo-substituted piperidine compounds, pharmaceutical compositions containing them, and methods of using them, including methods for treating substance addiction, panic disorder, anxiety, post-traumatic stress disorder, pain, depression, seasonal affective disorder, an eating disorder, or hypertension.
    Type: Application
    Filed: February 10, 2017
    Publication date: May 9, 2019
    Inventors: Theodore M. Kamenecka, Jörg Holenz, Steven Wesolowski, Yuanjun He, Roland Bürli
  • CYCLOPROPYL AMIDE DERIVATIVES
    Publication number: 20150216861
    Abstract: Disclosed herein is at least one cyclopropyl amide derivative, at least one pharmaceutical composition comprising at least one cyclopropyl amide derivative disclosed herein, and at least one method of using at least one cyclopropyl amide derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith.
    Type: Application
    Filed: April 13, 2015
    Publication date: August 6, 2015
    Inventors: James Arnold, Andrew Todd Brugel, Scott Throner, Steven Wesolowski, Phil Edwards, Andrew Griffin, Thierry Groblewski, Denis Labrecque
  • Cyclopropyl amide derivatives
    Patent number: 9029381
    Abstract: Disclosed herein is at least one cyclopropyl amide derivative, at least one pharmaceutical composition comprising at least one cyclopropyl amide derivative disclosed herein, and at least one method of using at least one cyclopropyl amide derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith.
    Type: Grant
    Filed: November 21, 2011
    Date of Patent: May 12, 2015
    Assignee: Astrazeneca AB
    Inventors: James Arnold, Todd Andrew Brugel, Scott Throner, Steven Wesolowski, Phil Edwards, Andrew Griffin, Thierry Groblewski, Denis Labrecque
  • Dibenzothiazepine derivatives and uses thereof—424
    Patent number: 8653257
    Abstract: Compounds the following formula: wherein Z is as described in the specification, pharmaceutically acceptable salts thereof, compositions comprising the same, and methods of treating bipolar disorder, an anxiety disorder, a mood disorder or schizophrenia or other psychotic disorder with said compounds.
    Type: Grant
    Filed: April 12, 2012
    Date of Patent: February 18, 2014
    Assignee: Astrazeneca AB
    Inventors: Dean Brown, James R. Damewood, Phil Edwards, James Hulsizer, James Campbell Muir, M. Edward Pierson, Jr., Ashokkumar Bhikkappa Shenvi, Steven Wesolowski, Dan Widzowski, Michael Wood
  • DIBENZOTHIAZEPINE DERIVATIVES AND USES THEREOF - 424
    Publication number: 20120202991
    Abstract: Compounds the following formula: wherein Z is as described in the specification, pharmaceutically acceptable salts thereof, compositions comprising the same, and methods of treating bipolar disorder, an anxiety disorder, a mood disorder or schizophrenia or other psychotic disorder with said compounds.
    Type: Application
    Filed: April 12, 2012
    Publication date: August 9, 2012
    Inventors: Dean Brown, James R. Damewood, Phil Edwards, James Hulsizer, James Campbell Muir, M. Edward Pierson, JR., Ashokkumar Bhikkappa Shenvi, Steven Wesolowski, Dan Widzowski, Michael Wood
  • Dibenzothiazepine derivatives and uses thereof—424
    Patent number: 8158618
    Abstract: Compounds the following formula: wherein Z is as described in the specification, pharmaceutically acceptable salts thereof, compositions comprising the same, and methods of treating bipolar disorder, an anxiety disorder, a mood disorder or schizophrenia or other psychotic disorder with said compounds.
    Type: Grant
    Filed: June 19, 2009
    Date of Patent: April 17, 2012
    Assignee: AstraZeneca AB
    Inventors: Dean Brown, James R. Damewood, Phil Edwards, James Hulsizer, James Campbell Muir, M. Edward Pierson, Jr., Ashokkumar Bhikkappa Shenvi, Steven Wesolowski, Dan Widzowski, Michael Wood
  • Cyclopropyl Amide Derivatives '978
    Publication number: 20120065193
    Abstract: Disclosed herein is at least one cyclopropyl amide derivative, at least one pharmaceutical composition comprising at least one cyclopropyl amide derivative disclosed herein, and at least one method of using at least one cyclopropyl amide derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith.
    Type: Application
    Filed: November 21, 2011
    Publication date: March 15, 2012
    Inventors: James Arnold, Andrew Todd Brugel, Scott Throner, Steven Wesolowski, Phil Edwards, Andrew Griffin, Thierry Groblewski, Denis Labrecque
  • Cyclopropyl amide derivatives
    Patent number: 8063215
    Abstract: Disclosed herein is at least one cyclopropyl amide derivative, at least one pharmaceutical composition comprising at least one cyclopropyl amide derivative disclosed herein, and at least one method of using at least one cyclopropyl amide derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith.
    Type: Grant
    Filed: August 21, 2008
    Date of Patent: November 22, 2011
    Assignee: AstraZeneca AB
    Inventors: James Arnold, Todd Andrew Brugel, Scott Throner, Steven Wesolowski, Phil Edwards, Andrew Griffin, Thierry Groblewski, Denis Labrecque
  • Dibenzothiazepine Derivatives and Use Thereof
    Publication number: 20110160184
    Abstract: Compounds the following formula: wherein Z is as described in the specification, pharmaceutically acceptable salts thereof, compositions comprising the same, and methods of treating bipolar disorder, an anxiety disorder, a mood disorder or schizophrenia or other psychotic disorder with said compounds.
    Type: Application
    Filed: June 18, 2009
    Publication date: June 30, 2011
    Applicant: ASTRAZENECA AB
    Inventors: Dean Brown, Steven Wesolowski, Dan Widzowski, James R. Damewood, M. Edward Pierson, Jr., Michael Wood, Philip Edwards, James Hulsizer, Ashokkumar Bhikkappa Shenvi, James Campbell Muir
  • Spirocyclopropyl Piperidine Derivatives
    Publication number: 20100168105
    Abstract: Disclosed herein is at least one piperidine derivative, at least one pharmaceutical composition comprising at least one piperidine derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith
    Type: Application
    Filed: May 23, 2008
    Publication date: July 1, 2010
    Inventors: Peter Bernstein, Dean Brown, Joseph Cacciola, Phil Edwards, James Folmer, Thierry Groblewski, Mark Sylvester, Steven Wesolowski
  • Spirocyclobutyl Piperidine Derivatives
    Publication number: 20100130477
    Abstract: Disclosed herein is at least one spirocyclobutyl piperidine derivative, at least one pharmaceutical composition comprising at least one spirocyclobutyl piperidine derivative disclosed herein, and at least one method of using at least one spirocyclobutyl piperidine derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith.
    Type: Application
    Filed: November 23, 2009
    Publication date: May 27, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Peter Bernstein, Dean Brown, Andrew Griffin, Maxime C. Tremblay, Steven Wesolowski
  • DIBENZOTHIAZEPINE DERIVATIVES AND USES THEREOF - 424
    Publication number: 20090318415
    Abstract: Compounds the following formula: wherein Z is as described in the specification, pharmaceutically acceptable salts thereof, compositions comprising the same, and methods of treating bipolar disorder, an anxiety disorder, a mood disorder or schizophrenia or other psychotic disorder with said compounds.
    Type: Application
    Filed: June 19, 2009
    Publication date: December 24, 2009
    Applicant: AstraZeneca AB
    Inventors: Dean Brown, James R. Damewood, Phil Edwards, James M. Hulsizer, James Campbell Muir, M. Edward Pierson, Jr., Ashokkumar Bhikkappa Shenvi, Steven Wesolowski, Dan Widzowski, Michael Wood
  • Compounds
    Publication number: 20090076064
    Abstract: Disclosed are compounds of Formula (I) wherein G, R2, A, D and E are as described in the specification, or pharmaceutically-acceptable salts, or in vivo-hydrolysable precursors thereof. Also disclosed herein is at least one method of making, at least one pharmaceutical composition containing, and at least one method for using at least one compound in accordance with Formula I.
    Type: Application
    Filed: January 3, 2007
    Publication date: March 19, 2009
    Applicant: ASTRAZENECA AB
    Inventors: Rebecca Urbanek, Dean Brown, Gary Steelman, William Blackwell, Steven Wesolowski, Xia Wang
  • Cyclopropyl Amide Derivatives 978
    Publication number: 20090076020
    Abstract: Disclosed herein is at least one cyclopropyl amide derivative, at least one pharmaceutical composition comprising at least one cyclopropyl amide derivative disclosed herein, and at least one method of using at least one cyclopropyl amide derivative disclosed herein for treating at least one histamine H3 receptor associated condition therewith.
    Type: Application
    Filed: August 21, 2008
    Publication date: March 19, 2009
    Applicant: ASTRAZENECA AB
    Inventors: James Arnold, Todd Andrew Brugel, Scott Throner, Steven Wesolowski, Phil Edwards, Andrew Griffin, Thierry Groblewski, Denis Labrecque
  • Novel Mchr1 Antagonists and Their Use for the Treatment of Mchr1 Mediated Conditions and Disorders
    Publication number: 20080269275
    Abstract: Compounds of Formula I wherein R1, D, R2, A and R3 are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: May 29, 2006
    Publication date: October 30, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Dean Brown, William Blackwell, Frances M. McLaren, Volker Schnecke, Reed W. Smith, Gary Steelman, Xia Wang, Rebecca Urbanek, Steven Wesolowski
  • Piperidine Derivatives as Histamine H3 Receptor Ligands
    Publication number: 20080064706
    Abstract: Compounds of formula: wherein Ar1 and Q are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the treatment of depression.
    Type: Application
    Filed: July 27, 2005
    Publication date: March 13, 2008
    Applicant: AstraZeneca AB
    Inventors: James Folmer, Simon Hunt, Peter Hamley, Steven Wesolowski