Patents by Inventor Steven Wishnies

Steven Wishnies has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for direct biomolecule identification by matrix-assisted laser desorption ionization (MALDI) mass spectrometry
    Publication number: 20070114375
    Abstract: The present invention relates to the use of post source decay (PSD) or collision induced dissociation (CID) direct tissue (DT) MALDI-TOF or DT-MALDI-TOF-TOF mass spectrographic identification of biological molecules in a tissue or cellular sample without the need for further protein extraction. This method provides for studying cells or tissues by direct tissue MALDI (DT-MALDI), thereby substituting in situ protein release for further protein extraction. Mass/intensity data was processed with Mascot© software interrogation of the NCBI database. These results are proof of principle that DT-MALDI, combined with bioinformatics, can directly identify proteins in cells and tissues from their mass spectra.
    Type: Application
    Filed: September 29, 2006
    Publication date: May 24, 2007
    Inventors: Paul Pevsner, Frederick Naftolin, Douglas Miller, Dean Hillman, Brian Stall, Steven Wishnies