Patents by Inventor Steven Wittenberger

Steven Wittenberger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • (1S,5S)-3-(5,6-DICHLORO-3-PYRIDINYL)-3,6-DIAZABICYCLO[3.2.0]HEPTANE
    Publication number: 20080070891
    Abstract: The present invention discloses (1S,5S)-3-(5,6-dichloro-3-pyridinyl)-3,6-diazabicyclo[3.2.0]heptane, salts thereof, and its use to treat pain and other disorders associated with the nicotinic acetylcholine receptor.
    Type: Application
    Filed: August 14, 2007
    Publication date: March 20, 2008
    Inventors: Michael Buckley, Jianguo Ji, Geoff Zhang, Rodger Henry, Weili Wang, Gregory Wayne, Wenke Li, Timothy Towne, Steven Wittenberger, Steven Hannick, Brian Kotecki, Bryan Macri, Timothy Robbins
  • Synthesis of (2S,5R)-5-ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile
    Publication number: 20080058528
    Abstract: A process for making (2S,5R)-5-ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile and salts thereof, and intermediates used in the process are disclosed.
    Type: Application
    Filed: July 19, 2007
    Publication date: March 6, 2008
    Inventors: Todd McDermott, Seble Wagaw, Kenneth Engstrom, Jorge Gandarilla, Albert Kruger, Michael Rozema, Michael Fickes, Steven Wittenberger, Lakshmi Bhagavatula, Thomas Borchardt
  • Octahydro-pyrrolo[3,4-b]pyrrole Derivatives
    Publication number: 20070232612
    Abstract: Octahydro-pyrrolo[3,4-b]pyrrole derivatives are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands, Octahydro-pyrrolo[3,4-b]pyrrole compounds, methods for using such compounds, compositions for making them, and processes for preparing such compounds are disclosed herein.
    Type: Application
    Filed: February 13, 2007
    Publication date: October 4, 2007
    Inventors: Marlon Cowart, Chen Zhao, Minghua Sun, Lawrence Black, Guo Zheng, Robert Gregg, Geoff Zhang, Ahmand Sheikh, Xiaochun Lou, Rodger Henry, David Barnes, Lawrence Kolaczkowski, Anthony Haight, Sou-Jen Chang, Steven Wittenberger, Michael Fickes
  • Endothelin antagonists
    Publication number: 20060229280
    Abstract: A compound of the formula (I): or a pharmaceutically acceptable salt thereof is disclosed, as well as processes for and intermediates in the preparation thereof, and a method of antagonizing endothelin.
    Type: Application
    Filed: February 23, 2005
    Publication date: October 12, 2006
    Inventors: Martin Winn, Steven Boyd, Charles Hutchins, Hwan-Soo Jae, Andrew Tasker, Thomas von Geldern, Jeffrey Kester, Bryan Sorensen, Bruce Szczepankiewicz, Kenneth Henry, Gang Liu, Steven Wittenberger, Steven King
  • Preparation of quinoline-substituted carbonate and carbamate derivatives
    Publication number: 20060128962
    Abstract: The invention relates to a process for preparing quinoline-substituted carbonate and carbamate compounds, which are important intermediates in the synthesis of 6-O-substituted macrolide antibiotics. The process employs metal-catalyzed coupling reactions to provide a carbonate or carbamate of formula (I) or (II) or a substrate that can be reduced to obtain the same.
    Type: Application
    Filed: February 6, 2006
    Publication date: June 15, 2006
    Inventors: Michael Allen, Ramiya Premchandran, Sou-Jen Chang, Stephen Condon, John DeMattei, Steven King, Lawrence Kolaczkowski, Sukumar Manna, Paul Nichols, Hemant Patel, Subhash Patel, Daniel Plata, Eric Stoner, Jien-Heh Tien, Steven Wittenberger
  • (1S,5S)-3-(5,6-DICHLORO-3-PYRIDINYL)-3,6-DIAZABICYCLO[3.2.0]HEPTANE
    Publication number: 20060035936
    Abstract: The present invention discloses (1S,5S)-3-(5,6-dichloro-3-pyridinyl)-3,6-diazabicyclo[3.2.0]heptane, salts thereof, and its use to treat pain and other disorders associated with the nicotinic acetylcholine receptor.
    Type: Application
    Filed: July 7, 2005
    Publication date: February 16, 2006
    Inventors: Michael Buckley, Jianguo Ji, Geoff Zhang, Rodger Henry, Weili Wang, Gregory Wayne, Wenke Li, Timothy Towne, Steven Wittenberger, Steven Hannick, Brian Kotecki, Bryan Macri, Timothy Robbins
  • Aminobenzoxazoles as therapeutic agents
    Publication number: 20060025383
    Abstract: A compound of Formula (I), wherein the substituents are as defined herein, which are useful as kinase inhibitors.
    Type: Application
    Filed: February 3, 2005
    Publication date: February 2, 2006
    Inventors: Neil Wishart, Michael Friedman, Lee Arnold, Bryant Yang, Shannon Fix-Stenzel, Anna Ericsson, Michael Michaelides, Xiao-Dong Qian, James Holms, Douglas Steinman, Zhengping Tian, Steven Wittenberger