Abstract: A thermal therapy system includes at least one Peltier device having a heating side and a cooling side; a cold fluid channel adjacent the cooling side of the at least one Peltier device, and a hot fluid channel adjacent the heating side of the at least one Peltier device. A controllable cooling fluid pump in fluid communication with the cold fluid channel drives cooling fluid to an applicator pad, and an independently-controllable heating fluid pump in fluid communication with the hot fluid channel drives hot fluid to the applicator pad.

Abstract: A thermal therapy system includes at least one Peltier device having a heating side and a cooling side; a cold fluid reservoir adjacent the cooling side of the Peltier device, and a hot fluid reservoir adjacent the heating side of the Peltier device. A controllable cooling fluid pump in fluid communication with the cold fluid reservoir drives cooling fluid to an applicator pad, and an independently-controllable heating fluid pump in fluid communication with the hot fluid reservoir drives hot fluid to the applicator pad.

Abstract: A personal water and additive apparatus includes a first container; a manifold having a water passageway and an additive passageway, the water passageway and additive passageway intersecting to form a single mixing passageway; a first tube connecting the first container to the water passageway of the manifold, the combination of the first tube and the water passageway defining a water channel; a second container; a second tube connecting the second container to the additive passageway of the manifold, the combination of the second tube and the additive passageway defining an additive channel; an outlet tube having one end connected to the mixing passageway of the manifold; a check valve disposed in the water channel; and a flow regulator that controls flow in at least one of the water passageway and the additive passageway.

Abstract: A laser energy soft tissue aspiration device comprises a cannula defining an aspiration lumen and having one or more aspiration inlet ports at a distal end. A laser energy transmission guide delivers laser energy from the proximal end of the cannula to the distal end which can be inserted to a tissue removal site within a patient. Reciprocating longitudinal motion of the cannula along with suction provided within the lumen can cause soft tissue to be suctioned into the lumen for removal. Laser energy contained within the lumen and directed by an optical delivery system can ablate soft tissue pulled within the lumen. The optical delivery system can further protect the terminal point of the laser energy transmission guide, from which, the laser energy can be delivered.

Abstract: A laser energy soft tissue aspiration device comprises a cannula defining an aspiration lumen and having one or more aspiration inlet ports at a distal end. A laser energy transmission guide delivers laser energy from the proximal end of the cannula to the distal end which can be inserted to a tissue removal site within a patient. Reciprocating longitudinal motion of the cannula along with suction provided within the lumen can cause soft tissue to be suctioned into the lumen for removal. Laser energy contained within the lumen and directed by an optical delivery system can ablate soft tissue pulled within the lumen. The optical delivery system can further protect the terminal point of the laser energy transmission guide by isolating it, or removing it from the flow of aspirated tissue.

Abstract: A laser energy soft tissue aspiration device comprises a cannula defining an aspiration lumen and having one or more aspiration inlet ports at a distal end. A laser energy transmission guide delivers laser energy from the proximal end of the cannula to the distal end which can be inserted to a tissue removal site within a patient. Reciprocating longitudinal motion of the cannula along with suction provided within the lumen can cause soft tissue to be suctioned into the lumen for removal. Laser energy contained within the lumen and directed by an optical delivery system can ablate soft tissue pulled within the lumen. The optical delivery system can further protect the terminal point of the laser energy transmission guide, from which, the laser energy can be delivered.

Abstract: A personal water and additive apparatus includes a first container; a manifold having a water passageway and an additive passageway, the water passageway and additive passageway intersecting to form a single mixing passageway; a first tube connecting the first container to the water passageway of the manifold, the combination of the first tube and the water passageway defining a water channel; a second container; a second tube connecting the second container to the additive passageway of the manifold, the combination of the second tube and the additive passageway defining an additive channel; an outlet tube having one end connected to the mixing passageway of the manifold; a check valve disposed in the water channel; and a flow regulator that controls flow in at least one of the water passageway and the additive passageway.

Abstract: A personal water and additive apparatus includes a first container; a manifold having a water passageway and an additive passageway, the water passageway and additive passageway intersecting to form a single mixing passageway; a first tube connecting the first container to the water passageway of the manifold, the combination of the first tube and the water passageway defining a water channel; a second container; a second tube connecting the second container to the additive passageway of the manifold, the combination of the second tube and the additive passageway defining an additive channel; an outlet tube having one end connected to the mixing passageway of the manifold; a check valve disposed in the water channel; and a flow regulator that controls flow in at least one of the water passageway and the additive passageway.

Abstract: A method and device for reducing mitral regurgitation. An elongated body is positioned in a coronary sinus of a patient in a vicinity of a heart mitral valve posterior leaflet. The body is adapted to straighten a natural curvature of at least a portion of the coronary sinus in the vicinity of the posterior leaflet to move a posterior annulus anteriorly, which in turn moves the posterior leaflet anteriorly, thereby to improve leaflet coaptation.

Abstract: A method and apparatus for reducing mitral regurgitation. The apparatus is inserted into the coronary sinus of a patient in the vicinity of the posterior leaflet of the mitral valve, the apparatus being adapted to straighten the natural curvature of at least a portion of the coronary sinus in the vicinity of the posterior leaflet of the mitral valve, whereby to move the posterior annulus anteriorly and thereby improve leaflet coaptation and reduce mitral regurgitation.

Abstract: Apparatus for resecting a diseased heart valve, the apparatus comprising: a body portion; a first handle and a second handle; a cutting blade; a set of retaining arms; a pass-off tool having a first attachment device configured to selectively engage the first handle attached to the body portion so as to allow placement of the second handle of the body portion adjacent to the diseased heart valve, and a controller tool having a second attachment device at the distal end thereof, the second attachment device configured to selectively engage the second handle attached to the body portion so as to allow positioning of the body portion adjacent to the diseased heart valve, a cutting blade actuator configured to cause the cutting blade to selectively rotate, and a retaining arm actuator configured to selectively position the set of retaining arms from the contracted state to the expanded state.

Abstract: A fixation band for affixing a prosthetic heart valve to tissue having proximal and distal annular portions positionable relative to one another, the proximal and distal annular portions each having a proximal and distal sides, the proximal side of the distal annular portion and the distal side of the proximal annular portion being oriented toward one another, and a prosthetic heart valve being attachable to one of the distal side of the distal annular portion and the proximal side of the proximal annular portion; staples configured between the distal side of the proximal annular portion and the proximal side of the distal annular portion; and a compression device operative between the proximal and distal annular portions for selectively positioning the proximal and distal annular members toward one another for compressing the staples therebetween and deploying the staples into tissue so as to affix the prosthetic heart valve to tissue.

Abstract: A method for reducing mitral regurgitation includes deploying deforming matter into a selected one of (i) a mitral valve annulus adjacent a posterior leaflet, and (ii) tissue adjacent the mitral valve annulus and proximate the posterior leaflet, to cause conformational change in the mitral valve annulus to increase mitral valve leaflet coaptation.

Abstract: A novel system for performing a heart valve annuloplasty. The system involves the use of a plication band. In one embodiment, the annulus of the valve is reduced by constriction of the plication band itself. More particularly, each plication band enters the tissue at two or more points which are spaced from one other by a distance which is dictated by the geometry of the plication band. Subsequent constriction of the plication band causes these points to move toward each other, thereby constricting the tissue trapped between these points and thus reducing the overall circumference of the valve annulus. In a second embodiment, the annulus of the valve is reduced by linking multiple plication bands to one other, using a linkage construct, and then using a shortening of the length of the linkage construct between each plication band so as to gather the tissue between each plication band, whereby to reduce the overall circumference of the valve annulus.

Abstract: Apparatus for reducing mitral regurgitation, by applying a force to the wall of the coronary sinus so as to force the posterior leaflet anteriorly and thereby reduce mitral regurgitation.

Abstract: A method of performing a medical procedure on target tissue within the body includes immobilizing the target tissue with an immobilization device, positioning an insertion tool (e.g., a needle, a needle and marker wire, a needle gun, etc.) to be inserted into the target tissue on the immobilization device based on at least one reading of the target tissue, and inserting the insertion tool into the target tissue. An immobilization device for performing methods includes a frame assembly, a tissue immobilization assembly coupled to the frame assembly, the tissue immobilization assembly including a structure adapted to immobilize tissue, and a needle assembly releasably connectable to the frame assembly. The needle assembly includes a needle capable of being inserted into the immobilized tissue.

Abstract: Apparatus for reducing mitral regurgitation, including a bendable elongated body adapted to be inserted into the coronary sinus of a patient in the vicinity of the posterior leaflet of the mitral valve, the elongated body being adjustable between a first configuration adapted to be delivered into the coronary sinus and a second configuration adapted to exert a force onto the posterior annulus. The body includes a flexible spine having a proximal end and a distal end, and a flexible wire mounted on the spine and having a distal end fixed to the spine proximate to the distal end of the spine, and having a proximal portion extending from the proximal end of the spine. Axial movement of the wire causes a change in the spine from the first configuration to the second configuration to exert the force on the posterior annulus and thereby reduce mitral regurgitation.

Abstract: The present invention comprises a method for deploying an aortic valve prosthesis. This valve prosthesis may include any of the known aortic valves including, but not limited to, stented and unstented bioprosthetic valves, stented mechanical valves, and expandable or self-expanding valves, whether biological or artificial. The method involves the steps of: making a first opening leading to the left atrium; passing a valve prosthesis through the opening and into a cardiac chamber of the left side of the heart using a first manipulation instrument; making a second opening in the arterial system and advancing one end of a second manipulation instrument through the arterial opening and into the aforementioned cardiac chamber; securing the second manipulation instrument to the valve prosthesis; and using the second manipulation instrument to retract at least some portion of the valve prosthesis out of the aforementioned cardiac chamber.

Abstract: A method and apparatus for reducing mitral regurgitation. The apparatus is inserted into the coronary sinus of a patient in the vicinity of the posterior leaflet of the mitral valve, the apparatus being adapted to straighten the natural curvature of at least a portion of the coronary sinus in the vicinity of the posterior leaflet of the mitral valve, whereby to move the posterior annulus anteriorly and thereby improve leaflet coaptation and reduce mitral regurgitation.

Abstract: A personal water and additive apparatus includes a first container; a manifold having a water passageway and an additive passageway, the water passageway and additive passageway intersecting to form a single mixing passageway; a first tube connecting the first container to the water passageway of the manifold, the combination of the first tube and the water passageway defining a water channel; a second container; a second tube connecting the second container to the additive passageway of the manifold, the combination of the second tube and the additive passageway defining an additive channel; an outlet tube having one end connected to the mixing passageway of the manifold; a check valve disposed in the water channel; and a flow regulator that controls flow in at least one of the water passageway and the additive passageway.