Patents by Inventor Steven YEO
Steven YEO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230273448Abstract: An illumination system includes a surface configured to have an imaging target placed thereon, a light source, a beam splitter and at least a first mirror. The beam splitter is configured to split the beam of light from the light source and the first mirror is configured to reflect a first beam from the beam splitter onto the surface with the imaging target. An imaging system includes an imaging surface configured to have an imaging target placed thereon, a mirror, and a capturing device. The capturing device is configured to capture an image of the imaging target through a path of emitted light that extends from the imaging target, reflects off of the mirror, and to the capturing device. The mirror, the capturing device, or both are configured to move in a diagonal direction with respect to the imaging surface to reduce a length of the path of emitted light. Systems and methods to calibrate an imaging system to remove or reduce non-uniformities within images of samples due to imaging system properties.Type: ApplicationFiled: January 24, 2023Publication date: August 31, 2023Inventors: Mingsong CHEN, Benyong SHI, Tiong Han TOH, Huei Steven YEO
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Patent number: 11592679Abstract: An illumination system includes a surface configured to have an imaging target placed thereon, a light source, a beam splitter and at least a first mirror. The beam splitter is configured to split the beam of light from the light source and the first mirror is configured to reflect a first beam from the beam splitter onto the surface with the imaging target. An imaging system includes an imaging surface configured to have an imaging target placed thereon, a mirror, and a capturing device. The capturing device is configured to capture an image of the imaging target through a path of emitted light that extends from the imaging target, reflects off of the mirror, and to the capturing device. The mirror, the capturing device, or both are configured to move in a diagonal direction with respect to the imaging surface to reduce a length of the path of emitted light. Systems and methods to calibrate an imaging system to remove or reduce non-uniformities within images of samples due to imaging system properties.Type: GrantFiled: October 13, 2017Date of Patent: February 28, 2023Assignee: LIFE TECHNOLOGIES HOLDINGS PTE LIMITEDInventors: Mingsong Chen, Benyong Shi, Tiong Han Toh, Huei Steven Yeo
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Patent number: 10931872Abstract: A method to maximize use of the field of view for an imaging system is provided herein. An imaging device can be part of the imaging system and include a detection unit and an alignment unit. The method includes capturing an initial image of an object and then calculating a rotational angle and zoom factor for the object in order to maximize the object's footprint within the field of view. Once the calculations are complete a computer can instruct the detection and alignment units to reconfigure their orientations relative to the object.Type: GrantFiled: August 21, 2019Date of Patent: February 23, 2021Assignees: LIFE TECHNOLOGIES HOLDINGS PTE LIMITED, PIERCE BIOTECHNOLOGY, INC.Inventors: Yanpeng Cao, Suk Hong, Tiong Han Toh, Steven Yeo, Benyong Shi, Kok Siong Teo, Brian Webb
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Patent number: 10627638Abstract: An illumination system includes a surface configured to have an imaging target placed thereon, a light source, a beam splitter and at least a first mirror. The beam splitter is configured to split the beam of light from the light source and the first mirror is configured to reflect a first beam from the beam splitter onto the surface with the imaging target. An imaging system includes an imaging surface configured to have an imaging target placed thereon, a mirror, and a capturing device. The capturing device is configured to capture an image of the imaging target through a path of emitted light that extends from the imaging target, reflects off the mirror, and to the capturing device. The mirror, the capturing device, or both are configured to move in a diagonal direction with respect to the imaging surface to reduce a length of the path of emitted light. Systems and methods to calibrate an imaging system to remove or reduce non-uniformities within images of samples due to imaging system properties.Type: GrantFiled: September 5, 2018Date of Patent: April 21, 2020Assignee: LIFE TECHNOLOGIES HOLDING PTE LIMITEDInventors: Mingsong Chen, Benyong Shi, Tiong Han Toh, Steven Yeo, Soo Fan Phua
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Publication number: 20200112677Abstract: A method to maximize use of the field of view for an imaging system is provided herein. An imaging device can be part of the imaging system and include a detection unit and an alignment unit. The method includes capturing an initial image of an object and then calculating a rotational angle and zoom factor for the object in order to maximize the object's footprint within the field of view. Once the calculations are complete a computer can instruct the detection and alignment units to reconfigure their orientations relative to the object.Type: ApplicationFiled: August 21, 2019Publication date: April 9, 2020Inventors: Yanpeng Cao, Suk Hong, Tiong Han Toh, Steven Yeo, Benyong Shi, Kok Siong Teo, Brian Webb
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Patent number: 10432857Abstract: A method to maximize use of the field of view for an imaging system is provided herein. An imaging device can be part of the imaging system and include a detection unit and an alignment unit. The method includes capturing an initial image of an object and then calculating a rotational angle and zoom factor for the object in order to maximize the object's footprint within the field of view. Once the calculations are complete a computer can instruct the detection and alignment units to reconfigure their orientations relative to the object.Type: GrantFiled: October 13, 2017Date of Patent: October 1, 2019Assignees: LIFE TECHNOLOGIES HOLDINGS PTE LIMITED, PIERCE BIOTECHNOLOGY, INC.Inventors: Yanpeng Cao, Suk Hong, Tiong Han Toh, Steven Yeo, Benyong Shi, Kok Siong Teo, Brian Webb
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Publication number: 20190193081Abstract: A thermal cycler is provided. The thermal cycler comprises a tray assembly. The tray assembly comprises a main body made of a first material having a first thermal conductivity. The tray assembly further comprises an adaptor made of a second material having a thermal conductivity that is greater than the thermal conductivity of the first material. The thermal cycler also includes a control block configured to control the temperature of the one or more nucleotide samples. The thermal cycler further includes a thermal cover sized and positioned to at least partially cover the plurality of vessels. The thermal cycler further includes a sample block including one or more depressions configured to receive a plurality of vessels containing one or more nucleotide samples.Type: ApplicationFiled: December 20, 2018Publication date: June 27, 2019Inventors: Huei Steven YEO, Soo Yong LAU, Cong JIANG
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Publication number: 20190126281Abstract: A biological analysis system is provided. The system comprises a sample block assembly. The sample block assembly comprises a sample block configured to accommodate a sample holder, the sample holder configured to receive a plurality of samples. The system also comprises a control system configured to cycle the plurality of samples through a series of temperatures. The system further comprises an automated tray comprising a slide assembly, the tray configured to reversibly slide the sample block assembly from a closed to an open position to allow user access to the plurality of sample holders.Type: ApplicationFiled: August 29, 2018Publication date: May 2, 2019Inventors: Yong CHU, Jeffrey MARKS, Jacob FREUDENTHAL, Mingsong CHEN, Tiong Han TOH, Mauro AGUANNO, Lik Seng LAU, Lian Seng LOH, Kok Siong TEO, Zeng Wei CHU, Xin MATHERS, Michael UY, Huei Steven YEO, Kuan Moon BOO, Way Xuang LEE, Chin Yong KOO, Wei Fuh TEO, Soo Yong LAU, Hon Siu SHIN, Zeqi TAN, Thomas WESSEL, David WOO
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Publication number: 20180373049Abstract: An illumination system includes a surface configured to have an imaging target placed thereon, a light source, a beam splitter and at least a first mirror. The beam splitter is configured to split the beam of light from the light source and the first mirror is configured to reflect a first beam from the beam splitter onto the surface with the imaging target. An imaging system includes an imaging surface configured to have an imaging target placed thereon, a mirror, and a capturing device. The capturing device is configured to capture an image of the imaging target through a path of emitted light that extends from the imaging target, reflects off the mirror, and to the capturing device. The mirror, the capturing device, or both are configured to move in a diagonal direction with respect to the imaging surface to reduce a length of the path of emitted light. Systems and methods to calibrate an imaging system to remove or reduce non-uniformities within images of samples due to imaging system properties.Type: ApplicationFiled: September 5, 2018Publication date: December 27, 2018Inventors: Mingsong CHEN, Benyong SHI, Tiong Han TOH, Steven YEO, Soo Fan PHUA
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Publication number: 20180124313Abstract: A method to maximize use of the field of view for an imaging system is provided herein. An imaging device can be part of the imaging system and include a detection unit and an alignment unit. The method includes capturing an initial image of an object and then calculating a rotational angle and zoom factor for the object in order to maximize the object's footprint within the field of view. Once the calculations are complete a computer can instruct the detection and alignment units to reconfigure their orientations relative to the object.Type: ApplicationFiled: October 13, 2017Publication date: May 3, 2018Inventors: Yanpeng CAO, Suk HONG, Tiong Han TOH, Steven YEO, Benyong SHI, Kok Siong TEO, Brian WEBB
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Publication number: 20180120575Abstract: An illumination system includes a surface configured to have an imaging target placed thereon, a light source, a beam splitter and at least a first mirror. The beam splitter is configured to split the beam of light from the light source and the first mirror is configured to reflect a first beam from the beam splitter onto the surface with the imaging target. An imaging system includes an imaging surface configured to have an imaging target placed thereon, a mirror, and a capturing device. The capturing device is configured to capture an image of the imaging target through a path of emitted light that extends from the imaging target, reflects off of the mirror, and to the capturing device. The mirror, the capturing device, or both are configured to move in a diagonal direction with respect to the imaging surface to reduce a length of the path of emitted light. Systems and methods to calibrate an imaging system to remove or reduce non-uniformities within images of samples due to imaging system properties.Type: ApplicationFiled: October 13, 2017Publication date: May 3, 2018Inventors: Mingsong CHEN, Benyong SHI, Tiong Han TOH, Steven YEO
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Publication number: 20160230210Abstract: An instrument for biological analysis includes a base, an excitation source, an optical sensor, an excitation optical system, and an emission optical system. The base is configured to receive a sample holder comprising a plurality of biological samples. The optical sensor is configured to receive emissions from the biological samples in response to the excitation source. The instrument may additionally include a sensor lens enclosed by a lens case and a focusing mechanism including a gear that engages the lens case, the focusing mechanism being accessible outside the enclosure for adjusting a focus. The may instrument further include a sensor aperture dispose along an emission optical path and a blocking structure disposed to cooperate with the sensor aperture such that none of the reflected radiation from an illuminated surface near the sample holder is received by the optical sensor that does not also reflect off another surface of the instrument.Type: ApplicationFiled: February 5, 2016Publication date: August 11, 2016Inventors: Mingsong CHEN, Kuan Moon BOO, Tiong Han TOH, Mauro AGUANNO, Soo Yong LAU, Huei Steven YEO, Wei Fuh TEO
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Patent number: D865218Type: GrantFiled: November 10, 2017Date of Patent: October 29, 2019Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Xin Mathers, Sandro Klein, Tiong Han Toh, Huei Steven Yeo
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Patent number: D965170Type: GrantFiled: October 23, 2020Date of Patent: September 27, 2022Assignees: LIFE TECHNOLOGIES CORPORATION, LIFE TECHNOLOGIES HOLDINGS PTE LIMITEDInventors: Beng Heng Lim, Siu Wee Hon, Huei Steven Yeo, Joshua Mead, Roy Thompson, Xin Mathers, Victor Shapiro