Patents by Inventor Stewart Douglas Nuttall

Stewart Douglas Nuttall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AMYLOID-BETA PEPTIDE CRYSTAL STRUCTURE
    Publication number: 20140039155
    Abstract: The invention relates provides a novel crystal structure of the fibrillogenic part of amyloid ?-peptide (A?). More specifically the crystal structure is A?-IgNAR and, accordingly the present invention also relates to selecting and/or designing compounds that modulate amyloid ?-peptide (A?) activity using techniques such as in silico screening and crystal soaking experiments. The invention further relates to compounds and methods for inhibiting interaction between amyloid ?-peptide (A?) monomers, more particularly, inhibiting or disrupting amyloid ?-peptide (A?) oligomer formation and toxic activity.
    Type: Application
    Filed: August 9, 2013
    Publication date: February 6, 2014
    Applicant: Commonwealth Scientific and Industrial Research Organisation
    Inventors: Stewart Douglas NUTTALL, Victor Anatolievich STRELTSOV, Joseph Noozhumurry VARGHESE, Vidanagamage Chandana EPA
  • Amyloid-beta peptide crystal structure
    Patent number: 8524863
    Abstract: The invention relates provides a novel crystal structure of the fibrillogenic part of amyloid ?-peptide (A?). More specifically the crystal structure is A?-IgNAR and, accordingly the present invention also relates to selecting and/or designing compounds that modulate amyloid ?-peptide (A?) activity using techniques such as in silico screening and crystal soaking experiments. The invention further relates to compounds and methods for inhibiting interaction between amyloid ?-peptide (A?) monomers, more particularly, inhibiting or disrupting amyloid ?-peptide (A?) oligomer formation and toxic activity.
    Type: Grant
    Filed: October 6, 2009
    Date of Patent: September 3, 2013
    Assignee: Commonwealth Scientific and Industrial Research Organisation
    Inventors: Stewart Douglas Nuttall, Victor Anatolievich Streltsov, Joseph Noozhumurry Varghese, Vidanagamage Chandana Epa
  • AMYLOID-BETA PEPTIDE CRYSTAL STRUCTURE
    Publication number: 20110269938
    Abstract: The invention relates provides a novel crystal structure of the fibrillogenic part of amyloid ?-peptide (A?). More specifically the crystal structure is A?-IgNAR and, accordingly the present invention also relates to selecting and/or designing compounds that modulate amyloid ?-peptide (A?) activity using techniques such as in silico screening and crystal soaking experiments. The invention further relates to compounds and methods for inhibiting interaction between amyloid ?-peptide (A?) monomers, more particularly, inhibiting or disrupting amyloid ?-peptide (A?) oligomer formation and toxic activity.
    Type: Application
    Filed: October 6, 2009
    Publication date: November 3, 2011
    Applicant: Commonwealth Scientific and Industrial Research Organisation
    Inventors: Stewart Douglas Nuttall, Victor Anatolievich Streltsov, Joseph Noozhumurry Varghese, Vidanagamage Chandana Epa
  • V-Like Domain Binding Molecules
    Publication number: 20080305988
    Abstract: The present invention relates to binding moieties comprising at least one monomeric V-like domain (VLD) derived from a non-antibody ligand, the at least one monomeric V-like domain being characterised in that at least one CDR loop structure or part thereof is modified or replaced such that the solubility of the modified VLD is improved when compared with the unmodified VLD.
    Type: Application
    Filed: May 15, 2008
    Publication date: December 11, 2008
    Inventors: Gregory Coia, Maria Galanis, Peter John Hudson, Robert Alexander Irving, Stewart Douglas Nuttall
  • V-like domain binding molecules and polynucleotides encoding therefor
    Patent number: 7405288
    Abstract: The present invention relates to binding moieties comprising at least one monomeric V-like domain (VLD) derived from a non-antibody ligand, the at least one monomeric V-like domain being characterised in that at least one CDR loop structure or part thereof is modified or replaced such that the solubility of the modified VLD is improved when compared with the unmodified VLD.
    Type: Grant
    Filed: October 27, 2006
    Date of Patent: July 29, 2008
    Assignee: Diatech Pty. Ltd.
    Inventors: Maria Galanis, Peter John Hudson, Robert Alexander Irving, Stewart Douglas Nuttall
  • V-like domain binding molecules
    Patent number: 7166697
    Abstract: The present invention relates to binding moieties comprising at least one monomeric V-like domain (VLD) derived from a non-antibody ligand, the at least one monomeric V-like domain being characterized in that at least one CDR loop structure or part thereof is modified or replaced such that the solubility of the modified VLD is improved when compared with the unmodified VLD.
    Type: Grant
    Filed: March 5, 1999
    Date of Patent: January 23, 2007
    Assignee: Diatech Pty. Ltd.
    Inventors: Maria Galanis, Peter John Hudson, Robert Alexander Irving, Stewart Douglas Nuttall