Abstract: The invention relates to vaccine compositions for inducing an immune response to a coronavirus in a subject, and uses thereof. In particular, the vaccine comprises of a chimeric or fusion protein comprising a) a N-terminal secretion signal peptide; b) an amino acid sequence of the receptor binding domain (RBD) of a spike protein of a coronavirus; and c) a C-terminal domain comprising a transmembrane region and a cytoplasmic region. In a preferred embodiment, the signal peptide, RBD, transmembrane region, and cytoplasmic region are derived from SARS-CoV-2, and that the vaccine composition is formulated as a lipid nanoparticle (LNP).

Abstract: A wire grid polarizer (WGP) can include an array of support-ribs on a substrate. Sides of the support-ribs can be inclined to one side. A wire can be applied on an upper-side and distal end of each support-rib, each wire being separate from wires on adjacent support-ribs. The WGP can be made with reduced or no etching.

Abstract: A method of making a polarizer can include applying a liquid with solid inorganic nanoparticles dispersed throughout a continuous phase, then forming this into a different phase including a solid, interconnecting network of the inorganic nanoparticles. This method can improve manufacturability and reducing manufacturing cost. This method can be used to provide an antireflective coating, to provide a protective coating on polarization structures, to provide thin films for optical properties, or to form the polarization structures themselves.

Abstract: A process for producing a 3D article by additive manufacture is provided. The method includes the steps of: forming a meltpool on an already-existing part of the article using heat supplied to the article by a gas metal arc welding device having one or more consumable electrodes, and moving the meltpool relative thereto; simultaneously feeding into the moving meltpool: (i) the one or more consumable electrodes of the gas metal arc welding device to provide a first material feed rate into the meltpool, and (ii) a non-electrode, supplementary feedstock to provide a second material feed rate into the meltpool, whereby a layer of material is deposited and fused on the already-existing part; and repeating the forming and moving, and the feeding steps to build up successive layers of material, and thereby produce the 3D article. The ratio of the first material feed rate to the second material feed rate is varied in performance of the feeding step. A related process for surface cladding an article is also provided.

Abstract: Monitoring apparatus for measuring the respiratory rate of a subject comprises an upper arm unit attached to a subject's upper arm in use and containing at least one movement sensor and a photoplethysmograph configured to monitor blood volume within the subject's upper arm while the upper arm unit is worn on the subject's upper arm. The output from the photoplethysmograph and movement sensor(s) are processed to calculate and output an estimate of the rate of respiration of the subject. Respiratory cycle induced variations in the photoplethysmograph signal and movement sensor signals can be independently determined and there is a greater confidence in the calculated respiratory rate when these independent calculations give consistent readings. If there is insufficient confidence, no rate of respiration is displayed.

Abstract: The invention relates to a photovoltaic roof covering comprising a base tile having an anchor portion to anchor the base tile to part of a roof in use and wherein a spacer is provided to support a portion of another overlaid base tile in use by spacing the overlaid tile from the photovoltaic panel. Also included is a roof covering with a base tile having a first planar upper face and a second opposing lower face. The base tile comprises an anchor portion located towards one end of the second lower face of the base tile and is configured to anchor the base tile to part of a roof structure in use. A connecting portion is configured to connect the base tile to an adjacent base tile in use. The roof covering further comprises a rectilinear cover panel having upper and lower opposing faces and a width that is smaller relative to a width of the first planar upper face of the base tile.

Abstract: Monitoring apparatus for measuring the respiratory rate of a subject comprises an upper arm unit attached to a subject's upper arm in use and containing at least one movement sensor and a photoplethysmograph configured to monitor blood volume within the subject's upper arm while the upper arm unit is worn on the subjects upper arm. The output from the photoplethysmograph and movement sensor(s) are processed to calculate and output an estimate of the rate of respiration of the subject. Respiratory cycle induced variations in the photoplethysmograph signal and movement sensor signals can be independently determined and there is a greater confidence in the calculated respiratory rate when these independent calculations give consistent readings. If there is insufficient confidence, no rate of respiration is displayed.

Abstract: A system enhances a system design to incorporate safety measures. The system receives a system design for processing through various stages of design using design tools, for example electronic design automation tools for introducing safety features in a circuit design. The system receives safety requirements for the system design, the safety requirements specifying safety measures for the system design. The system generates from the safety requirements, a safety specification storing a set of commands. The system generates a system design enhanced with safety measures. The enhanced system design it generated for at least a subset of the plurality of tools. A tool processes the generated safety specification to implement safety measures in the system design according to the received safety requirements.

Abstract: The present application is at least directed to a system including a processor and non-transitory memory including computer-executable instructions, which when executed by the processor, perform receiving, via a user operating the system, a selection of a mode for recognizing objects. The processor is also configured to execute the instructions of causing a camera operably coupled to the system to operate in the selected mode for recognizing objects. The processor is further configured to execute the instructions of receiving, via the user operating the system, an image of a selected object. The processor is even further configured to execute the instructions of evaluating, via a trained machine learning model, one or more attributes of the selected object. The processor is yet further configured to execute the instructions of generating an image description based on at least a subset of the evaluated one or more attributes.

Abstract: The invention relates to a photovoltaic roof covering comprising a base tile having an anchor portion to anchor the base tile to part of a roof in use and wherein a spacer is provided to support a portion of another overlaid base tile in use by spacing the overlaid tile from the photovoltaic panel. Also included is a roof covering with a base tile having a first planar upper face and a second opposing lower face. The base tile comprises an anchor portion located towards one end of the second lower face of the base tile and is configured to anchor the base tile to part of a roof structure in use. A connecting portion is configured to connect the base tile to an adjacent base tile in use. The roof covering further comprises a rectilinear cover panel having upper and lower opposing faces and a width that is smaller relative to a width of the first planar upper face of the base tile.

Abstract: A system enhances a system design to incorporate safety measures. The system receives a system design for processing through various stages of design using design tools, for example electronic design automation tools for introducing safety features in a circuit design. The system receives safety requirements for the system design, the safety requirements specifying safety measures for the system design. The system generates from the safety requirements, a safety specification storing a set of commands. The system generates a system design enhanced with safety measures. The enhanced system design it generated for at least a subset of the plurality of tools. A tool processes the generated safety specification to implement safety measures in the system design according to the received safety requirements.

Abstract: Monitoring apparatus for measuring the respiratory rate of a subject comprises an upper arm unit attached to a subject's upper arm in use and containing at least one movement sensor and a photoplethysmograph configured to monitor blood volume within the subject's upper arm while the upper arm unit is worn on the subjects upper arm. The output from the photoplethysmograph and movement sensor(s) are processed to calculate and output an estimate of the rate of respiration of the subject. Respiratory cycle induced variations in the photoplethysmograph signal and movement sensor signals can be independently determined and there is a greater confidence in the calculated respiratory rate when these independent calculations give consistent readings. If there is insufficient confidence, no rate of respiration is displayed.

Abstract: An automated cleaning apparatus fashioned for programmed cleaning of a surface wherein the apparatus comprises: a unit housing for an enclosed mechanism, a conductive contact strip provided on a surface, a controller having a processor confirmed to control the output of translational device movement. The apparatus is prompted to travel along the cross-sectional area of the surface in a translational motion, wherein buildup of any undesirable substance is removed from the surface by protruding bristles from the housing of the mechanism that remain in contact with the surface.

Abstract: An exercise device comprising; a platform, a first limb attachment means, a first extendable cord attached to the first limb attachment means, the first extendable cord being at least partially located within the platform, and a tensioning means within the platform, wherein the tensioning means can be adjusted to alter the resistance of the first extendable cord to extension.

Abstract: Systems, methods, and media bearing computer-executable instructions are provided for responding to a search query directed to a request for activities in a specified location. In response, a location-action data store storing a plurality of location-activity records is accessed and location-activity responses (each identifying an activity at a specific location) are returned. The location-activity records are aggregated from check-in data from a plurality of users from one or more social networking services.

Abstract: A wringer connector for connecting a mop handle to a lever of a mop wringer to allow the mop handle to actuate the lever. The wringer connector comprises a first connector securable to one of the lever and the mop handle and engageable with the one of the lever and the mop handle to rotationally fix the first connector with respect to the one of the lever and the mop handle; and a second connector extending from the first connector and engageable with the other of the lever and the mop handle to functionally connect the mop handle to the lever.

Abstract: An exercise device comprising; a platform, a first limb attachment means, a first extendable cord attached to the first limb attachment means, the first extendable cord being at least partially located within the platform, and a tensioning means within the platform, wherein the tensioning means can be adjusted to alter the resistance of the first extendable cord to extension.

Abstract: A static cycling machine includes a base assembly. A front post support structure is arranged on the base assembly. A front post assembly is arranged on the front post support structure and is angled forward with respect to a support substrate, the front post assembly being adjustable in length and configured to permit a handlebar assembly to be mounted thereon. A rear post support structure is arranged on the base assembly. A rear post assembly is arranged on the rear post support structure and is angled rearward with respect to the support substrate, the rear post assembly being adjustable in length and configured to permit a seat assembly to be mounted thereon. Linear actuators are arranged on respective support structures and operatively engaged with respective post assemblies to adjust the lengths of the post assemblies. A control system controls operation of the linear actuators. A crank assembly is arranged on at least one of the base and support structures.

Abstract: The free-space gesture MIDI controller technique described herein marries the technologies embodied in a free-space gesture controller with MIDI controller technology, allowing a user to control an infinite variety of electronic musical instruments through body gesture and pose. One embodiment of the free-space gesture MIDI controller technique described herein uses a human body gesture recognition capability of a free-space gesture control system and translates human gestures into musical actions. Rather than directly connecting a specific musical instrument to the free-space gesture controller, the technique generalizes its capability and instead outputs standard MIDI signals, thereby allowing the free-space gesture control system to control any MIDI-capable instrument.

Abstract: A static cycling machine includes a support assembly and a drive assembly. A frame assembly is mounted on the support assembly. The frame assembly includes a seat tube assembly extending from the drive assembly, the seat tube assembly being adjustable in length. A down tube assembly extends from the drive assembly, the down tube assembly being adjustable in length. A handlebar assembly is mounted on the down tube assembly. A fork assembly is connected to the handlebar assembly and is adjustable in length. The seat tube, down tube, handlebar and fork assemblies are connected to each other such that at least the dimensions of the frame assembly can be adjusted by adjusting the lengths of the tube assemblies. A driven wheel assembly is operatively connected to the drive assembly so that work applied to the drive assembly can be transmitted to the wheel assembly. Actuators are operatively engaged with the frame assembly to adjust dimensions of the frame assembly.