Abstract: In one embodiment, a non-invasively adjustable spinal system for treatment of a subject having spondylolisthesis includes a first implantable actuator having at least one anchoring structure, the anchoring structure configured to facilitate securement of the first implantable actuator to a portion of the sacrum of the subject. The non-invasively adjustable spinal system can further include an adjustment element, configured to be coupled to the first implantable actuator, the adjustment element having an engagement structure configured to engage at least one transverse process of a lumbar vertebra of the subject. The non-invasively adjustable spinal system can further include a driving element, wherein remote activation of the driving element causes movement of the adjustment element in relation to the first implantable actuator.

Abstract: In one embodiment, a non-invasively adjustable spinal system for treatment of a subject having spondylolisthesis includes a first implantable actuator having at least one anchoring structure, the anchoring structure configured to facilitate securement of the first implantable actuator to a portion of the sacrum of the subject. The non-invasively adjustable spinal system can further include an adjustment element, configured to be coupled to the first implantable actuator, the adjustment element having an engagement structure configured to engage at least one transverse process of a lumbar vertebra of the subject. The non-invasively adjustable spinal system can further include a driving element, wherein remote activation of the driving element causes movement of the adjustment element in relation to the first implantable actuator.

Abstract: In one embodiment, a non-invasively adjustable spinal system for treatment of a subject having spondylolisthesis includes a first implantable actuator having at least one anchoring structure, the anchoring structure configured to facilitate securement of the first implantable actuator to a portion of the sacrum of the subject. The non-invasively adjustable spinal system can further include an adjustment element, configured to be coupled to the first implantable actuator, the adjustment element having an engagement structure configured to engage at least one transverse process of a lumbar vertebra of the subject. The non-invasively adjustable spinal system can further include a driving element, wherein remote activation of the driving element causes movement of the adjustment element in relation to the first implantable actuator.

Abstract: A method for treating a complex fracture with a variable length nail is provided. The nail is configured for at least 5 mm of axial length change in each direction. The method involves making a first hole or incision in the skin of the patient in proximity to a fractured long bone and at least partially clearing a canal through the center of the long bone. The variable length nail is inserted into the canal and securing a distraction shaft and a housing of the nail to separate portions of the fractured long bone. The hole or incision is allowed or caused to close. An external adjustment device comprising at least one rotatable magnet is placed in proximity to the patient's skin. The external adjustment device is operated so that a magnetic field of the at least one rotatable magnet of the external adjustment device causes the rotatable permanent magnet of the variable length nail to rotate, causing either extension or retraction of the distraction shaft relative to the housing.

Abstract: A method for treating a complex fracture with a variable length nail is provided. The nail is configured for at least 5 mm of axial length change in each direction. The method involves making a first hole or incision in the skin of the patient in proximity to a fractured long bone and at least partially clearing a canal through the center of the long bone. The variable length nail is inserted into the canal and securing a distraction shaft and a housing of the nail to separate portions of the fractured long bone. The hole or incision is allowed or caused to close. An external adjustment device comprising at least one rotatable magnet is placed in proximity to the patient's skin. The external adjustment device is operated so that a magnetic field of the at least one rotatable magnet of the external adjustment device causes the rotatable permanent magnet of the variable length nail to rotate, causing either extension or retraction of the distraction shaft relative to the housing.

Abstract: In one embodiment, a non-invasively adjustable spinal system for treatment of a subject having spondylolisthesis includes a first implantable actuator having at least one anchoring structure, the anchoring structure configured to facilitate securement of the first implantable actuator to a portion of the sacrum of the subject. The non-invasively adjustable spinal system can further include an adjustment element, configured to be coupled to the first implantable actuator, the adjustment element having an engagement structure configured to engage at least one transverse process of a lumbar vertebra of the subject. The non-invasively adjustable spinal system can further include a driving element, wherein remote activation of the driving element causes movement of the adjustment element in relation to the first implantable actuator.

Abstract: A method for treating a fracture with a variable length nail is provided. The nail is configured for at least 5 mm of axial length change in each direction. An incision is made in proximity to a fractured bone and canal is cleared through the center of the bone. The variable length nail is inserted into the canal and a distraction shaft and a housing are secured to separate portions of the fractured bone. The incision is allowed or caused to close. An external adjustment device with at least one rotatable magnet is placed in proximity to the patient's skin. The external adjustment device is operated so that a magnetic field of the at least one rotatable magnet of the external adjustment device causes the rotatable permanent magnet of the variable length nail to rotate, causing either extension or retraction of the distraction shaft relative to the housing.

Abstract: A method for treating a fracture with a variable length nail is provided. The nail is configured for at least 5 mm of axial length change in each direction. An incision is made in proximity to a fractured bone and canal is cleared through the center of the bone. The variable length nail is inserted into the canal and a distraction shaft and a housing are secured to separate portions of the fractured bone. The incision is allowed or caused to close. An external adjustment device with at least one rotatable magnet is placed in proximity to the patient's skin. The external adjustment device is operated so that a magnetic field of the at least one rotatable magnet of the external adjustment device causes the rotatable permanent magnet of the variable length nail to rotate, causing either extension or retraction of the distraction shaft relative to the housing.

Abstract: Embodiments of the present invention relate to automatically creating localized menus for interactive media such as, for example, DVD-Video menus, via a menu component comprising references to an instance of menu background data, a menu text template defining text positions and sets of menu texts in different texts. The menu is then derived by processing the menu component. This enables localized menus to be produced more cost-effectively and more quickly than in non-automated prior art methods.

Abstract: This invention concerns compositions for the treatment of urinary frequency, urinary urgency and urinary incontinence comprising (R)-N-[4-[2-[[2-hydroxy-2-(pyridin-3 -yl)ethyl]amino]ethyl]phenyl]-4-[4-(4-trifluoromethylphenyl)thiazol-2-yl]benzenesulfonamide and pharmaceutically acceptable salts thereof. In another aspect, this invention concerns combination therapy for urinary frequency, urinary urgency and urinary incontinence wherein one of the active agents is (R)-N-[4-[2-[[2-hydroxy-2-(pyridin-3-yl)ethyl]amino]ethyl]phenyl]-4-[4-(4-trifluoromethylphenyl)thiazol-2-yl]benzenesulfonamide and pharmaceutically acceptable salts thereof.

Abstract: This invention concerns compositions for the treatment of Lower Urinary Tract Symptoms (LUTS), and especially LUTS which results from benign prostatic hypertrophy. The compositions of the invention comprise a Beta-3 agonist described below, optionally in combination with a 5-alpha reductase inhibitor, or an NK-1 antagonist or an alpha-1 adrenergic antagonist or an anti-muscarinic agent. The invention also includes compositions comprising a beta-3 agonist and two additional active agents selected from a 5-alpha reductase inhibitor, an NK-1 antagonist, an alpha-1 adrenergic antagonist or an anti-muscarinic agent.

Abstract: This invention concerns compositions for the treatment of urinary frequency, urinary urgency and urinary incontinence comprising (R)-N-[4-[2-[[2-hydroxy-2-(pyridin-3-yl)ethyl]amino]ethyl]phenyl]-4-[4-(4-tri-fluoromethylphenyl)thiazol-2-yl]benzenesulfonamide and pharmaceutically acceptable salts thereof. In another aspect, this invention concerns combination therapy for urinary frequency, urinary urgency and urinary incontinence wherein one of the active agents is (R)-N-[4-[2-[[2-hydroxy-2-(pyridin-3-yl)ethyl]amino]ethyl]phenyl]-4-[4-(4-tri-fluoromethylphenyl)thiazol-2-yl]benzenesulfonamide and pharmaceutically acceptable salts thereof.

Abstract: Embodiments of the present invention relate to a data processing system and method for automatically testing a digital content player to ensure compliance with a video image data specification.

Abstract: Embodiments of the present invention relate to a data processing system and method for automatically testing, for example, a DVD to ensure compliance with an intended mode of operation. Tags or unique identifiers are embedded within the MPEG elementary video streams. These tags are detected and correlated against a test plan to determine whether or not the authored DVD is as intended.