Patents by Inventor Stuart A. Grossman
Stuart A. Grossman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10105555Abstract: The present invention discloses systems and methods for calculating the radiation doses received by circulating blood cells. The present method may be applicable for calculating the radiation doses by circulating blood cells through any site in a patient. The present invention also discloses computer systems for calculating radiation doses received by circulating blood cells in a patient.Type: GrantFiled: January 30, 2015Date of Patent: October 23, 2018Assignee: THE JOHNS HOPKINS UNIVERSITYInventors: Susannah Ellsworth, Eric Ford, Stuart A. Grossman, Robert Hobbs, Lawrence Kleinberg
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Patent number: 9775652Abstract: A bone plate system is provided. The system includes two or more fastener locks stacked on top of each other and located between two holes in a plate adapted to receive bone fasteners. An actuator is provided between the locks. As the actuator is advanced, the locks are moved sequentially into position, firstly, to prevent one or more bone fasteners from backing out of the plate while permitting the fasteners to angulate and, secondly, to lock the angulation of the bone fasteners while still providing back out protection in situ. An expandable bone plate having a top plate interconnected to a bottom plate by a rack and pinion is provided. The rotation of the pinion with a driver lengthens or shortens the plate incrementally for custom length adjustment. The length is fixed in position with the simple removal of the driver and no further step is required to lock the plate length.Type: GrantFiled: October 10, 2016Date of Patent: October 3, 2017Assignee: Mastros Innovations, LLCInventors: Moti Altarac, Joey Reglos, Michael Schneier, Brian Stuart Grossman, Michael Davis, Dale Lawrence Leibert, John Fredrick Stephani
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Publication number: 20170020579Abstract: A bone plate system is provided. The system includes two or more fastener locks stacked on top of each other and located between two holes in a plate adapted to receive bone fasteners. An actuator is provided between the locks. As the actuator is advanced, the locks are moved sequentially into position, firstly, to prevent one or more bone fasteners from backing out of the plate while permitting the fasteners to angulate and, secondly, to lock the angulation of the bone fasteners while still providing back out protection in situ. An expandable bone plate having a top plate interconnected to a bottom plate by a rack and pinion is provided. The rotation of the pinion with a driver lengthens or shortens the plate incrementally for custom length adjustment. The length is fixed in position with the simple removal of the driver and no further step is required to lock the plate length.Type: ApplicationFiled: October 10, 2016Publication date: January 26, 2017Inventors: Moti Altarac, Joey Reglos, Michael Schneier, Brian Stuart Grossman, Michael Davis, Dale Lawrence Leibert, John Fredrick Stephani
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Publication number: 20160339270Abstract: The present invention discloses systems and methods for calculating the radiation doses received by circulating blood cells. The present method may be applicable for calculating the radiation doses by circulating blood cells through any site in a patient. The present invention also discloses computer systems for calculating radiation doses received by circulating blood cells in a patient.Type: ApplicationFiled: January 30, 2015Publication date: November 24, 2016Inventors: Susannah ELLSWORTH, Eric FORD, Stuart A. GROSSMAN, Robert HOBBS, Lawrence KLEINBERG
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Patent number: 9486250Abstract: A bone plate system is provided. The system includes two or more fastener locks stacked on top of each other and located between two holes in a plate adapted to receive bone fasteners. An actuator is provided between the locks. As the actuator is advanced, the locks are moved sequentially into position, firstly, to prevent one or more bone fasteners from backing out of the plate while permitting the fasteners to angulate and, secondly, to lock the angulation of the bone fasteners while still providing back out protection in situ. An expandable bone plate having a top plate interconnected to a bottom plate by a rack and pinion is provided. The rotation of the pinion with a driver lengthens or shortens the plate incrementally for custom length adjustment. The length is fixed in position with the simple removal of the driver and no further step is required to lock the plate length.Type: GrantFiled: February 20, 2014Date of Patent: November 8, 2016Assignee: Mastros Innovations, LLC.Inventors: Moti Altarac, Joey Reglos, Michael Schneier, Brian Stuart Grossman, Michael Davis, Dale Lawrence Leibert, John Fredrick Stephani
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Publication number: 20160135901Abstract: A treatment simulator for providing information on physiological states and effects of treatment of neurological disease, comprising a computer, and an application configured to operate with the computer. The application is capable of: obtaining radiological imaging from the brain; obtaining anatomical information from the radiological imaging within a region of interest within the brain; constructing a physiological states model which assesses physiological states of the region of interest; locating sources of interstitial flow of particulate matter and obtaining fluid conductivities of paths of the interstitial flow utilizing the anatomical information and the physiological states model; and creating a flow model of the particulate matter which assesses velocities of flow and interstitial pressure variations utilizing the sources of interstitial flow and the fluid conductivities.Type: ApplicationFiled: December 22, 2015Publication date: May 19, 2016Inventors: Raghu Raghavan, Stuart A. Grossman
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Patent number: 9265577Abstract: Methods and systems for providing planning and dispensation of research and/or treatment for brain disease. Radiological information is generated in a region of interest in an area of the a brain of an individual using a radiological imaging system. A physiological states model is constructed which assesses physiological states of the region of interest. Locations of sources of interstitial fluid flow, fluid conductivities of paths, and anatomical information in the region of interest are obtained using the radiological imaging information. Velocities of the interstitial fluid flow in the region of interest are computed using the physiological states model, the locations of sources of interstitial flow, the fluid conductivities, and the anatomic information. A model of the area of the brain is created, the model including the region of interest.Type: GrantFiled: May 7, 2008Date of Patent: February 23, 2016Assignee: THE JOHNS HOPKINS UNIVERSITYInventors: Raghu Raghavan, Stuart A. Grossman
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Publication number: 20150230831Abstract: A bone plate system is provided. The system includes two or more fastener locks stacked on top of each other and located between two holes in a plate adapted to receive bone fasteners. An actuator is provided between the locks. As the actuator is advanced, the locks are moved sequentially into position, firstly, to prevent one or more bone fasteners from backing out of the plate while permitting the fasteners to angulate and, secondly, to lock the angulation of the bone fasteners while still providing back out protection in situ. An expandable bone plate having a top plate interconnected to a bottom plate by a rack and pinion is provided. The rotation of the pinion with a driver lengthens or shortens the plate incrementally for custom length adjustment. The length is fixed in position with the simple removal of the driver and no further step is required to lock the plate length.Type: ApplicationFiled: February 20, 2014Publication date: August 20, 2015Inventors: Moti Altarac, Joey Reglos, Michael Schneier, Brian Stuart Grossman, Michael Davis, Dale Lawrence Leibert, John Fredrick Stephani
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Publication number: 20130236524Abstract: Implants for delivery of therapeutic agents such as opioids, and the manufacture and uses of such implants are provided. In particular, subcutaneous drug delivery systems having a biocompatible thermoplastic elastomeric polymer matrix, a therapeutic agent embedded homogeneously in said matrix, and a biocompatible drug impermeable cross-linked silicone polymer coating said matrix and methods of making the same are provided.Type: ApplicationFiled: September 7, 2012Publication date: September 12, 2013Applicant: AXXIA PHARMACEUTICALS, LLCInventors: Richard J. HOLL, Katherine HARTMAN, Stuart A. Grossman, Wayne C. Pollock
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Publication number: 20120034306Abstract: The subject invention relates to implants for delivery of therapeutic agents such as opioids, and the manufacture and uses of such implants.Type: ApplicationFiled: April 19, 2010Publication date: February 9, 2012Inventors: Wayne C. Pollock, Stuart A. Grossman, Albert H. Owens, JR.
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Publication number: 20100303883Abstract: Implants are disclosed for delivery of therapeutic agents such as opioids and the manufacture and uses of such implants.Type: ApplicationFiled: October 17, 2008Publication date: December 2, 2010Applicant: AXXIA PHARMACEUTICALS, LLCInventors: Wayne C. Pollock, Stuart A. Grossman, Albert H. Owens
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Publication number: 20090024181Abstract: A treatment simulator for providing information on physiological states and effects of treatment of neurological disease, comprising a computer, and an application configured to operate with the computer. The application is capable of: obtaining radiological imaging from the brain; obtaining anatomical information from the radiological imaging within a region of interest within the brain; constructing a physiological states model which assesses physiological states of the region of interest; locating sources of interstitial flow of particulate matter and obtaining fluid conductivities of paths of the interstitial flow utilizing the anatomical information and the physiological states model; and creating a flow model of the particulate matter which assesses velocities of flow and interstitial pressure variations utilizing the sources of interstitial flow and the fluid conductivities.Type: ApplicationFiled: May 7, 2008Publication date: January 22, 2009Inventors: Raghu Raghavan, Stuart A. Grossman
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Patent number: 6126956Abstract: A non-abusable, non-inflammatory, biocompatible, non-biodegradable, subcutaneous, polymeric implant for the prolonged, controlled release of hydromorphone with near zero-order kinetics is described. Methods of alleviating cancer pain and treating opioid drug addiction with the implant are also described.Type: GrantFiled: December 22, 1998Date of Patent: October 3, 2000Assignee: Axxia TechnologiesInventors: Stuart A. Grossman, Kam W. Leong, Glenn J. Lesser, Hungnan Lo
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Patent number: 5858388Abstract: A non-abusable, non-inflammatory, biocompatible, non-biodegradable, subcutaneous, polymeric implant for the prolonged, controlled release of hydromorphone with near zero-order kinetics is described. Methods of alleviating cancer pain and treating opioid drug addiction with the implant are also described.Type: GrantFiled: January 30, 1997Date of Patent: January 12, 1999Assignee: Axxia TechnologiesInventors: Stuart A. Grossman, Kam W. Leong, Glenn J. Lesser, Hungnan Lo
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Patent number: 5633000Abstract: A non-abusable, non-inflammatory, biocompatible, non-biodegradable, subcutaneous, polymeric implant for the prolonged, controlled release of hydromorphone with near zero-order kinetics is described. Methods of alleviating cancer pain and treating opioid drug addiction with the implant are also described.Type: GrantFiled: June 23, 1994Date of Patent: May 27, 1997Assignee: Axxia TechnologiesInventors: Stuart A. Grossman, Kam W. Leong, Glenn J. Lesser, Hungnan Lo