Abstract: A system and method are provided which dynamically adapts to a changing economic environment by selecting or synthesizing an economic model from a set of economic models based on the selected model's ability to make accurate predictions about an actual economic market. The method and system each forms a space of different economic models, forms a behavioral landscape by extracting observables from executions of the economic models, and performs model selection and composite model synthesis through optimization over the behavioral landscape.

Abstract: A method and system for evolving electronic circuits based on defined rules. A first approach uses a network of nodes having established topological and behavioral relationships amongst themselves. An A/D converter is developed using this approach. A second approach employs software agents to create signal filters. The software agents are allowed to evolve in signal parameter space so as to match a reference signal, subject to established evolutionary rules and parameter space constraints. Narrowband and a low-pass filters can be formed using such agents.

Abstract: The present invention relates generally to a method and system for performing operations management in an environment of resources. More particularly, the present invention performs operations management by representing the resources with integrated circuits that find relations among the resources and combine related resources to form new resources.

Abstract: Technological change at the firm-level has commonly been modeled as random sampling from a fixed distribution of possibilities. Such models, however, typically ignore empirically important aspects of the firm's search process, notably the observation that the present state of the firm guides future innovation. In this paper we explicitly treat this aspect of the firm's search for technological improvements by introducing a “technology landscape” into an otherwise standard dynamic programming setting where the optimal strategy is to assign a reservation price to each possible technology. Search is modeled as movement, constrained by the cost of innovation, over the technology landscape. Simulations are presented on a stylized technology landscape while analytic results are derived using landscapes that are similar to Markov random fields.

Abstract: The present invention presents a comprehensive system and method for operations management which has the reliability and adaptability to handle failures and changes respectively within the economic environment. The present invention presents a framework of features which include technology graphs, landscape representations and automated markets to achieve the requisite reliability and adaptability.

Abstract: The invention provides a method of identifying nucleic acid molecules that contain cis acting nucleic acid elements. Also provided is a method of isolating nucleic acid binding factors. The invention also provides methods of identifying compounds that are cis acting nucleic acid element analogs, compounds that are nucleic acid binding factor analogs, compounds that selectively bind cis acting nucleic acid elements and compounds that selectively displace binding between a nucleic acid binding factor and a cis acting nucleic acid element or between nucleic acid binding factors. Also provided is a method of determining a binding state of a nucleic acid. Pluralities of isolated nucleic acid molecules containing cis acting nucleic acid elements, of isolated cis acting nucleic acid elements and of isolated nucleic acid binding factors are also provided.

Abstract: A method and system for evolving electronic circuits based on defined rules. A first approach uses a network of nodes having established topological and behavioral relationships amongst themselves. An A/D converter is developed using this approach. A second approach employs software agents to create signal filters. The software agents are allowed to evolve in signal parameter space so as to match a reference signal, subject to established evolutionary rules and parameter space constraints. Narrowband and a low-pass filters can be formed using such agents.

Abstract: The present invention is directed to production of a molecule having a predetermined property. In accordance with one embodiment, a library of initial candidate molecules that are at least somewhat dissimilar to a chosen target molecule or “targetshape” is generated. Variants of the initial candidates are generated and screened to identify intermediate candidates from among those variants that are either more or less similar to the targetshape. The process may be iterated by generating variants of the intermediate candidates and screening these variants to identify molecules further more or less similar to the targetshape.

Abstract: The present invention performs adaptive and robust command and control by identifying operation sequences that are outcome determinative or polyfunctional.

Abstract: The present invention relates to experimental and algorithmic methods for analysis of genetic regulatory networks. More particularly, the present invention provides methods of partitioning genes withing an organism into a plurality of groups and identification and characterization of correlations between genes and groups of genes in the genomic networks of real viruses, cells, and tissues.

Abstract: Technological change at the firm-level has commonly been modeled as random sampling from a fixed distribution of possibilities. Such models, however, typically ignore empirically important aspects of the firm's search process, notably the observation that the present state of the firm guides future innovation. In this paper we explicitly treat this aspect of the firm's search for technological improvements by introducing a “technology landscape” into an otherwise standard dynamic programming setting where the optimal strategy is to assign a reservation price to each possible technology. Search is modeled as movement, constrained by the cost of innovation, over the technology landscape. Simulations are presented on a stylized technology landscape while analytic results are derived using landscapes that are similar to Markov random fields.

Abstract: The invention provides a method of identifying nucleic acid molecules that contain cis acting nucleic acid elements. Also provided is a method of isolating nucleic acid binding factors. The invention also provides methods of identifying compounds that are cis acting nucleic acid element analogs, compounds that are nucleic acid binding factor analogs, compounds that selectively bind cis acting nucleic acid elements and compounds that selectively displace binding between a nucleic acid binding factor and a cis acting nucleic acid element or between nucleic acid binding factors. Also provided is a method of determining a binding state of a nucleic acid. Pluralities of isolated nucleic acid molecules containing cis acting nucleic acid elements, of isolated cis acting nucleic acid elements and of isolated nucleic acid binding factors are also provided.