Patents by Inventor Stuart Denham Shumway

Stuart Denham Shumway has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for treating cancer
    Patent number: 9655899
    Abstract: The instant invention relates to methods for the treatment of WEE1 kinase associated cancer by administering a WEE1 inhibitor, wherein the WEE1 inhibitor is WEE1-1 or a pharmaceutically acceptable salt thereof, or WEE1-2 or a pharmaceutically acceptable salt thereof. In another embodiment, the invention relates to a method for treating a WEE1 kinase associated cancer patient, comprising administering a WEE1 inhibitor, wherein the cancer cells of said patient to be treated are characterized by low expression levels of PKMYT1.
    Type: Grant
    Filed: November 22, 2013
    Date of Patent: May 23, 2017
    Assignee: Merck Sharp & Dohme Corp.
    Inventor: Stuart Denham Shumway
  • Compositions and methods for treating cancer
    Patent number: 9345705
    Abstract: The instant invention provides a method of treating a cancer, selected from the group consisting of breast cancer, melanoma, colorectal cancer, non-small cell lung cancer and ovarian cancer, by administering a combination of a WEE1 inhibitor and a CHK1 inhibitor, wherein the WEE1 inhibitor is MK-1775 or a pharmaceutically acceptable salt thereof, or MK-3652 or a pharmaceutically acceptable salt thereof, and the CHK1 inhibitor is MK-8776 or a pharmaceutically acceptable salt thereof, or SCH900444 or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: September 11, 2012
    Date of Patent: May 24, 2016
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Stuart Denham Shumway, Carlo Toniatti, Brian Scott Roberts, Melissa M. Martin
  • COMPOSITIONS AND METHODS FOR TREATING CANCER
    Publication number: 20160008361
    Abstract: The instant invention relates to methods for the treatment of WEE1 kinase associated cancer by administering a WEE1 inhibitor, wherein the WEE1 inhibitor is WEE1-1 or a pharmaceutically acceptable salt thereof, or WEE1-2 or a pharmaceutically acceptable salt thereof. In another embodiment, the invention relates to a method for treating a WEE1 kinase associated cancer patient, comprising administering a WEE1 inhibitor, wherein the cancer cells of said patient to be treated are characterized by low expression levels of PKMYT1.
    Type: Application
    Filed: November 22, 2013
    Publication date: January 14, 2016
    Applicant: Merck Sharp & Dohme Corp.
    Inventor: Stuart Denham Shumway
  • COMPOSITIONS AND METHODS FOR TREATING CANCER
    Publication number: 20140343071
    Abstract: The instant invention provides a method of treating a cancer, selected from the group consisting of breast cancer, melanoma, colorectal cancer, non-small cell lung cancer and ovarian cancer, by administering a combination of a WEE1 inhibitor and a CHK1 inhibitor, wherein the WEE1 inhibitor is MK-1775 or a pharmaceutically acceptable salt thereof, or MK-3652 or a pharmaceutically acceptable salt thereof, and the CHK1 inhibitor is MK-8776 or a pharmaceutically acceptable salt thereof, or SCH900444 or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: September 11, 2012
    Publication date: November 20, 2014
    Inventors: Stuart Denham Shumway, Carlo Toniatti, Brian Scott Roberts, Melissa M. Martin