Abstract: A bioelectric interface is provided. The bioelectric interface comprises a case having a channel configured to hold a nerve. An electrode array is slidably coupled to the case, wherein the electrode array comprises a number of electrode shanks. The case restricts movement of the electrode array to one degree of freedom toward or away from the nerve held in the channel for insertion of the electrode shanks into the nerve.

Abstract: Manufacturing a neural interface device. Forming a neural interface probe of an implantable microelectrode body. PECVD a first amorphous silicon carbide insulation layer, forming a thin film metal trace and interface pad on the first layer, the pad on a portion of the trace. PECVD a second amorphous silicon carbide insulation layer on the first layer and covering the trace and the pad. Forming an opening in the second layer to expose the pad to an ambient environment. Patterning the first and second layers to define the neural interface probe. The probe has a rectangular cuboid shape, a cross-sectional area perpendicularly transverse to a long axis length of the probe and through any perpendicularly transverse cross-section along the long axis length is less than about 50 microns. The layers are the principle material of construction of the probe.

Abstract: A neural interface device that comprises an implantable microelectrode body. The implantable microelectrode body includes a neural interface probe, which includes a thin film metal trace connected to an interface pad and an amorphous silicon carbide insulation. The amorphous silicon carbide insulation surrounds the thin film metal trace to form an outside surface of the neural interface probe. The interface pad is exposed to an ambient environment of the neural interface probe through an opening in the amorphous silicon carbide insulation. Methods of manufacturing the neural interface device are disclosed.

Abstract: A bioelectric interface is provided. The bioelectric interface comprises a case having a channel configured to hold a nerve. An electrode array is slidably coupled to the case, wherein the electrode array comprises a number of electrode shanks. The case restricts movement of the electrode array to one degree of freedom toward or away from the nerve held in the channel for insertion of the electrode shanks into the nerve.

Abstract: In one aspect, a neuromodulation device is described herein. In some embodiments, a neuromodulation device comprises a chamber operable to receive a nerve, at least one electrode disposed in the chamber, and a channel defined by two walls. In some embodiments, the channel of the device is in fluid communication with an interior of the chamber and an external surface of the device. In another aspect, methods of neuromodulation are described herein. In some embodiments, methods described herein can use one or more neuromodulation devices described herein.

Abstract: A neural interface device that comprises an implantable microelectrode body. The implantable microelectrode body includes a neural interface probe, which includes a thin film metal trace connected to an interface pad and an amorphous silicon carbide insulation. The amorphous silicon carbide insulation surrounds the thin film metal trace to form an outside surface of the neural interface probe. The interface pad is exposed to an ambient environment of the neural interface probe through an opening in the amorphous silicon carbide insulation. Methods of manufacturing the neural interface device are disclosed.

Abstract: Subdural arrays transmit electrocorticogram recordings wirelessly, across the patient's skull, allowing the craniotomy used for surgical placement of the arrays to be completely closed. In various embodiments, the arrays also respond to commands, applying signal patterns to the patient's brain for diagnostic and treatment purposes.

Abstract: Subdural arrays transmit electrocorticogram recordings wirelessly, across the patient's skull, allowing the craniotomy used for surgical placement of the arrays to be completely closed. In various embodiments, the arrays also respond to commands, applying signal patterns to the patient's brain for diagnostic and treatment purposes.

Abstract: Subdural arrays transmit electrocorticogram recordings wirelessly, across the patient's skull, allowing the craniotomy used for surgical placement of the arrays to be completely closed. In various embodiments, the arrays also respond to commands, applying signal patterns to the patient's brain for diagnostic and treatment purposes.

Abstract: An electro-optical device having an oxidatively coloring electrochromic layer of composition Mn.sub.x V.sub.y O.sub.z, where 0.05 x/y<1, x+2y<z<2x+(5/2)y, and x+y=1, with improved transmittance modulation, the Mn.sub.x V.sub.y O.sub.z providing complementary optical modulation to reductively coloring electrochromic materials in devices employing an all-thin-film configuration with a solid ion conducting electrolyte and in devices employing a laminated configuration with a polymeric ion conducting electrolyte.

Abstract: A biomedical device provided with a protective overlayer with high electronic resistivity and low permeability to H.sub.2 O; the protective overlayer comprising at least one thin film of amorphous silicon oxycarbide (a-SiOC:H) in which the oxygen/carbon ratio is such that the electronic resistivity of the a-SiOC:H is greater than 10.sup.14 .OMEGA.-cm and the H.sub.2 O permeability is less than 5.times.10.sup.14 molecules/sec-cm.sup.2.

Abstract: An electro-optical device comprising a series of thin films with an electrically controllable optical state provided with a protective overlayer that has a high optical transmittance and high resistance to penetration by H.sub.2 O. The protective overlayer is a film of amorphous silicon oxycarbide (a-SiOC:H) having an O to C ratio such that the optical absorption edge of the a-SiOC:H is 3 eV or greater and the H.sub.2 O transport through a 500 nm thick film of a-SiOC:H is 10.sup.12 molecules/cm.sup.2 -s or less.

Abstract: Polymer electrolytes comprising co-polymers of vinylic, protonic acids and N,N' dialkyl substituted acrylamides and methacrylamides with high anodic stability, reduced acidity and high mechanical stiffness suitable for electrochromic devices, such as windows, mirrors and information displays. A preferred embodiment of the invention is a co-polymer with a composition of 30% 2-acrylamido-2-methyl propane sulfonic acid, 50% N,N dimethyl acrylamide and 20% water by weight.

Abstract: A method for preparing an oxidatively coloring electrochromic layer of composition M.sub.y CrO.sub.2+x (0.33.ltoreq.y.ltoreq.2.0 and x.ltoreq.2) where M=Li, Na or K and an electrochromic devise employing this layer with improved transmittance modulation, improved thermal and environmental stability, and improved resistance to degradation in organic liquid and polymeric electrolytes. The M.sub.y CrO.sub.2+x provides complementary optical modulation to cathodically coloring materials in thin-film electrochromic glazings and electrochromic devices employing polymeric Li.sup.+ ion conductors.

Abstract: An oxidatively coloring electrochromic layer of composition M.sub.y CrO.sub.2+x (0.33.ltoreq.y.ltoreq.2.0 and x.ltoreq.2) where M=Li, Na or K with improved transmittance modulation, improved thermal and environmental stability, and improved resistance to degradation in organic liquid and polymeric electrolytes. The M.sub.y CrO.sub.2+x provides complementary optical modulation to cathodically coloring materials in thin-film electrochromic glazings and electrochromic devices employing polymeric Li.sup.+ ion conductors.

Abstract: An all solid-state variable transmission electrochromic device has a source of charge compensating ions. An inorganic oxide counterelectrode film which on reduction with the accompanying insertion of the charge compensating ions increases its transmission of light of predetermined wavelength is separated from a primary electrochromic film which on reduction with the accompanying insertion of the charge compensating ions decreases its transmission of light of predetermined wavelength by an insulating electrolyte film that transports the charge compensating ions. First and second electrodes are contiguous with the inorganic oxide counter electrode film and the primary electrochromic film, respectively, and separated by the three films.

Abstract: An all solid-state variable transmission electrochromic device has a source of charge compensating ions. An inorganic oxide counterelectrode film which on reduction with the accompanying insertion of the charge compensating ions increases its transmission of light of predetermined wavelength is separated from a primary electrochromic film which on reduction with the accompanying insertion of the charge compensating ions decreases its transmission of light of predetermined wavelength by an insulating electrolyte film that transports the charge compensating ions. First and second electrodes are contiguous with the inorganic oxide counter electrode film and the primary electrochromic film, respectively, and separated by the three films.