Patents by Inventor Stuart L. Cooper

Stuart L. Cooper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100190703
    Abstract: Provided herein are compositions and methods for binding outgrowth endothelial cells (OEC). The compositions consist of peptide ligands capable of binding OEC with high affinity and specificity. The compositions of the invention include peptides set forth in SEQ ID NO: 1-38 and variants and derivatives thereof. Compositions also include the nucleotide sequences encoding the peptides of the invention. The compositions find use in methods for the isolation of OEC and for the recruitment and retention of OEC to sites of therapeutic interest. Methods for the identification and isolation of other peptides capable of binding OEC are also provided.
    Type: Application
    Filed: March 5, 2008
    Publication date: July 29, 2010
    Applicants: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, NORTH CAROLINA STATE UNIVERSITY, THE OHIO STATE UNIVERSITY
    Inventors: Cam Patterson, Anka Veleva, Stuart L. Cooper
  • Patent number: 6579906
    Abstract: A novel cationic dendrimer biocide-silver nanocomposite and methods for its use as a biocide. The biocidal nanocomposites of the present invention are effective against a variety of microbial species, including anthrax. The invention is also highly stable and safe for exposure to human skin. The invention has applications as an antibiological warfare agents, antimicrobial agent for surface coatings and as a general biocide that is safe for human exposure.
    Type: Grant
    Filed: June 8, 2001
    Date of Patent: June 17, 2003
    Assignee: University of Delaware
    Inventors: Stuart L. Cooper, Chris Z. Chen
  • Publication number: 20030082133
    Abstract: A novel cationic dendrimer biocide-silver nanocomposite and methods for its use as a biocide. The biocidal nanocomposites of the present invention are effective against a variety of microbial species, including anthrax. The invention is also highly stable and safe for exposure to human skin. The invention has applications as an antibiological warfare agents, antimicrobial agent for surface coatings and as a general biocide that is safe for human exposure.
    Type: Application
    Filed: December 4, 2002
    Publication date: May 1, 2003
    Inventors: Stuart L. Cooper, Chris Z. Chen
  • Patent number: 6440405
    Abstract: Quaternary ammonium functionalized dendrimers are described which are suitable for controlling the growth of microorganisms. The quaternary ammonium functionalized dendrimer biocides of the present invention are effective against a wide variety of microbial species including bacteria, spores, yeast, fungi, mold and multicellular microorganisms.
    Type: Grant
    Filed: June 6, 2000
    Date of Patent: August 27, 2002
    Assignee: University of Delaware
    Inventors: Stuart L. Cooper, Chris Zhisheng Chen
  • Publication number: 20020022012
    Abstract: A novel cationic dendrimer biocide-silver nanocomposite and methods for its use as a biocide. The biocidal nanocomposites of the present invention are effective against a variety of microbial species, including anthrax. The invention is also highly stable and safe for exposure to human skin. The invention has applications as an antibiological warfare agents, antimicrobial agent for surface coatings and as a general biocide that is safe for human exposure.
    Type: Application
    Filed: June 8, 2001
    Publication date: February 21, 2002
    Inventors: Stuart L. Cooper, Chris Z. Chen
  • Patent number: 5674921
    Abstract: A radiation-curable prepolymer of a polyurethane endtipped with an hydroxy (acrylate or methacrylate) is disclosed. The polyurethane is derived from the reaction of a polyfunctional isocyanate with a hydrolyzable oligomer of an anhydrous cyclic ester of an hydroxy acid. Crosslinked polymers prepared by irradiating the prepolymers are also disclosed. The crosslinked polymers are bioabsorbable and biocompatible with bodily tissue, yet still maintain the outstanding mechanical properties one would expect from a polyurethane. The prepolymers and crosslinked polymers are especially well-suited for the fabrication of surgical devices, particularly wound closure devices such as surgical staples and clips, in a stereolithography apparatus.
    Type: Grant
    Filed: February 1, 1995
    Date of Patent: October 7, 1997
    Assignee: Ethicon, Inc.
    Inventors: Donald W. Regula, Michael F. Bregen, Stuart L. Cooper, Dennis D. Jamiolkowski, Rao S. Bezwada
  • Patent number: 5221724
    Abstract: Polysiloxane-containing polyurea and polyurea urethane block copolymers and devices formed therefrom are biocompatible and demonstrate improved physical and mechanical properties. The pre-reaction of an amine-terminated polysiloxane soft segment with an organic diisocyanate provides an oligomer that enhances the hydrophilic properties of the copolymer.
    Type: Grant
    Filed: November 19, 1990
    Date of Patent: June 22, 1993
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Chi Li, Stuart L. Cooper
  • Patent number: 5017664
    Abstract: Modified-polyurethane block copolymers and devices formed therefrom demonstrate excellent biocompatibilty and improved physical and mechanical properties. In a preferred embodiment, from about 5 to about 25 percent of urethane hydrogen atoms are replaced with propyl sulfonate and propyl carboxylate groups to provide the modified copolymer.
    Type: Grant
    Filed: April 5, 1989
    Date of Patent: May 21, 1991
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Timothy G. Grasel, Stuart L. Cooper
  • Patent number: 4880883
    Abstract: Modified-polyurethane block copolymers and devices formed therefrom demonstrate excellent biocompatibility and improved physical and mechanical properties. In a preferred embodiment, from about 5 to about 25 percent of urethane hydrogen atoms are replaced with propyl sulfonate and propyl carboxylate groups to provide the modified copolymer.
    Type: Grant
    Filed: June 3, 1987
    Date of Patent: November 14, 1989
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Timothy G. Grasel, Stuart L. Cooper