Patents by Inventor Stuart Le Grice

Stuart Le Grice has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HIV-2 envelope polypeptides
    Patent number: 5874533
    Abstract: Polypeptides which include at least one antigenic and/or immunogenic determinant of the envelope protein (env) of the HIV-2 virus and their production by recombinant DNA technology and the DNA sequences, expression vectors and transformed single-cell organisms used in this process are provided. A method for the detection of HIV antibodies or HIV viruses in human sera or in other biological fluids is also provided.
    Type: Grant
    Filed: March 15, 1994
    Date of Patent: February 23, 1999
    Assignee: Roche Diagnostic Systems, Inc.
    Inventors: Wilhelm Bannwarth, Patrick Caspers, Stuart Le Grice, Jan Mous
  • HIV-2 envelope polypeptides
    Patent number: 5780038
    Abstract: Polypeptides which include at least one antigenic and/or immunogenic determinant of the envelope protein (env) of the HIV-2 virus and their production by recombinant DNA technology and the DNA sequences, expression vectors and transformed single-cell organisms used in this process are provided. A method for the detection of HIV antibodies or HIV viruses in human sera or in other biological fluids is also provided.
    Type: Grant
    Filed: May 3, 1995
    Date of Patent: July 14, 1998
    Assignee: Roche Diagnostic Systems, Inc.
    Inventors: Wilhelm Bannwarth, Patrick Caspers, Stuart Le Grice, Jan Mous
  • HIV-2 envelope polypeptides
    Patent number: 5702918
    Abstract: Polypeptides which include at least one antigenic and/or immunogenic determinant of the envelope protein (env) of the HIV-2 virus and their production by recombinant DNA technology and the DNA sequences, expression vectors and transformed single-cell organisms used in this process are provided. A method for the detection of HIV antibodies or HIV viruses in human sera or in other biological fluids is also provided.
    Type: Grant
    Filed: May 5, 1995
    Date of Patent: December 30, 1997
    Assignee: Roche Diagnostic Systems, Inc.
    Inventors: Wilhelm Bannwarth, Patrick Caspers, Stuart Le Grice, Jan Mous
  • Gram-positive expression control sequences
    Patent number: 4868111
    Abstract: New gram-positive expression control DNA sequences useful in the expression of pro- or eukaryotic proteins in gram-positive organisms are provided having in the downstream direction of transcription a transcription initiation DNA sequence of gram-negative origin combined with a ribosome binding site-encoding DNA sequence, optionally a foreign gene and a transcription termination sequence. Also described are expression vectors containing these expression control DNA sequences and processes using same for the manufacture of pro- and eukaryotic polypeptides. In addition processes for the manufacture of such gram-positive expression control DNA sequences and such expression vectors are described.
    Type: Grant
    Filed: June 17, 1986
    Date of Patent: September 19, 1989
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Hermann Bujard, Stuart Le Grice