Patents by Inventor Stuart Leff

Stuart Leff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the treatment of parkinson's disease
    Publication number: 20060193841
    Abstract: A method of treating Parkinson's Disease in patients exhibiting increasing resistance to the administration of L-dopa due to loss of aromatic L-amino acid decarboxylic activity in striatal neurons comprises transfection of the caudate and/or putamen regions with a viral vector encoding AADC. The vector preferably has a promoter system provided for the expression of the AADC nucleic acid, and is injected at a slow rate, at a level designed to restore AADC activity to tissues undergoing progressive loss of that activity. The AADC renewed activity permits conversion of L-dopa, in the brain, to dopamine.
    Type: Application
    Filed: April 24, 2006
    Publication date: August 31, 2006
    Inventors: Ronald Mandel, Stuart Leff
  • Method for the treatment of Parkinson's Disease
    Publication number: 20050143330
    Abstract: A method of treating Parkinson's Disease in patients exhibiting increasing resistance to the administration of L-dopa due to loss of aromatic L-amino acid decarboxylic activity in striatal neurons comprises transfection of the caudate and/or putamen regions with a viral vector encoding AADC. The vector preferably has a promoter system provided for the expression of the AADC nucleic acid, and is injected at a slow rate, at a level designed to restore AADC activity to tissues undergoing progressive loss of that activity. The AADC renewed activity permits conversion of L-dopa, in the brain, to dopamine.
    Type: Application
    Filed: September 30, 2002
    Publication date: June 30, 2005
    Inventors: Ron Mandel, Stuart Leff