Abstract: A pile (270) within a bore (110) comprises a column (250). The column (250) comprises a stack of a plurality of pile sections (300) arranged end-to-end within the bore (110). There is a cured material (260) between at least a part of an outside surface of the column (250) and the surface of the bore (110). The cured material, for example grout, may be provided through channels in the pile sections.

Abstract: A method for multicast load balancing in a wireless network having a plurality of access points. The method includes setting a maximum Internet protocol multicast bandwidth for the access points, receiving an admissions control request from a client at one of the access points, and determining whether the admissions control request from the client is for an admitted or unadmitted multicast stream at the access point. The access point is responsive to the admissions control request for the admitted multicast stream by servicing the admitted multicast stream and to the admissions control request for the unadmitted multicast stream by servicing the unadmitted multicast stream where the bandwidth required for the unadmitted multicast stream, plus that portion of the access point bandwidth currently used for all existing downlink multicast streams, does not exceed the maximum internet protocol multicast bandwidth for the access point.

Abstract: An apparatus (10) for assessment, evaluation and grading of gemstones has a stage (11) upon which a gemstone may be supported, the stage being enclosed in a housing (15) that is impervious to light. At least one light source (14) located in the housing is adapted to project incident light onto the gemstone. There are means for rotating and tilting the stage so as to vary the orientation of the gemstone to the incident light. A digital camera (16) is located in the housing adjacent the or each light source and is adapted to take images of the gemstone based on reflection and/or refraction of the incident light. There are also information processing means for calibrating and analyzing the images, with the information processing means being programmed with an instruction set for color calibrating the images and then analyzing the color calibrated images by segmentation and histogram measurement.

Abstract: A method for multicast load balancing in a wireless network having a plurality of access points. The method includes setting a maximum Internet protocol multicast bandwidth for the access points, receiving an admissions control request from a client at one of the access points, and determining whether the admissions control request from the client is for an admitted or unadmitted multicast stream at the access point. The access point is responsive to the admissions control request for the admitted multicast stream by servicing the admitted multicast stream and to the admissions control request for the unadmitted multicast stream by servicing the unadmitted multicast stream where the bandwidth required for the unadmitted multicast stream, plus that portion of the access point bandwidth currently used for all existing downlink multicast streams, does not exceed the maximum internet protocol multicast bandwidth for the access point.

Abstract: A method for multicast load balancing in a wireless network having a plurality of access points. The method includes setting a maximum Internet protocol multicast bandwidth for the access points, receiving an admissions control request from a client at one of the access points, and determining whether the admissions control request from the client is for an admitted or unadmitted multicast stream at the access point. The access point is responsive to the admissions control request for the admitted multicast stream by servicing the admitted multicast stream and to the admissions control request for the unadmitted multicast stream by servicing the unadmitted multicast stream where the bandwidth required for the unadmitted multicast stream, plus that portion of the access point bandwidth currently used for all existing downlink multicast streams, does not exceed the maximum internet protocol multicast bandwidth for the access point.

Abstract: A compound of Formula (I): is useful in the treatment or prevention of a disease or medical condition mediated through glucokinase (GLK or GK), leading to a decreased glucose threshold for insulin secretion.

Abstract: (2S)-2-[1-(2-Chloro-6-cyano-phenyl)pyrazolo[4,5-e]pyrimidin-4-yl]oxy-3-[(1R)-2-hydroxy-1-methyl-ethoxy]-N-(5-methylpyrazin-2-yl)propanamide or a pharmaceutically acceptable salt thereof is useful in the treatment or prevention of a disease or medical condition mediated through glucokinase (GLK or GK), leading to a decreased glucose threshold for insulin secretion.

Abstract: A compound of formula (I): and pharmaceutically-acceptable salts thereof, wherein the variable groups are defined within; their use in the inhibition of 11?HSD1, processes for making them and pharmaceutical compositions comprising them are also described herein.

Abstract: (2S)-2-[1-(2-Chloro-6-cyano-phenyl)pyrazolo[4,5-e]pyrimidin-4-yl]oxy-3-[(1R)-2-hydroxy-1-methyl-ethoxy]-N-(5-methylpyrazin-2-yl)propanamide or a pharmaceutically acceptable salt thereof is useful in the treatment or prevention of a disease or medical condition mediated through glucokinase (GLK or GK), leading to a decreased glucose threshold for insulin secretion.

Abstract: Compounds of formula (I), or salts thereof, which inhibit acetyl CoA(acetyl coenzyme A):diacylglycerol acyltransferase (DGAT1) activity are provided, wherein, for example, R1 is optionally substituted phenyl or naphthyl; Ring A is selected from (3-6C)cycloalkyl, (5-12C)bicycloalkyl and phenyl; n is 0, 1 or 2; R2 is, for example, hydrogen, fluoro, chloro or hydroxy; Ring B is selected from (3-6C)cycloalkyl, (5-12C)bicycloalkyl and phenyl; L1 is a direct bond or a defined linker group and R3 is, for example, hydroxy, carboxy or (1-6C)alkoxycarbonyl; together with processes for their preparation, pharmaceutical compositions containing them and their use as medicaments.

Abstract: An apparatus (10) for assessment, evaluation and grading of gemstones has a stage (11) upon which a gemstone may be supported, the stage being enclosed in a housing (15) that is impervious to light. At least one light source (14) located in the housing is adapted to project incident light onto the gemstone. There are means for rotating and tilting the stage so as to vary the orientation of the gemstone to the incident light. A digital camera (16) is located in the housing adjacent the or each light source and is adapted to take images of the gemstone based on reflection and/or refraction of the incident light. There are also information processing means for calibrating and analysing the images, with the information processing means being programmed with an instruction set for colour calibrating the images and then analysing the colour calibrated images by segmentation and histogram measurement.

Abstract: A compound of Formula (I): is useful in the treatment or prevention of a disease or medical condition mediated through glucokinase (GLK or GK), leading to a decreased glucose threshold for insulin secretion.

Abstract: A method for multicast load balancing in a wireless network having a plurality of access points. The method includes setting a maximum Internet protocol multicast bandwidth for the access points, receiving an admissions control request from a client at one of the access points, and determining whether the admissions control request from the client is for an admitted or unadmitted multicast stream at the access point. The access point is responsive to the admissions control request for the admitted multicast stream by servicing the admitted multicast stream and to the admissions control request for the unadmitted multicast stream by servicing the unadmitted multicast stream where the bandwidth required for the unadmitted multicast stream, plus that portion of the access point bandwidth currently used for all existing downlink multicast streams, does not exceed the maximum internet protocol multicast bandwidth for the access point.

Abstract: A method for multicast load balancing in a wireless network having a plurality of access points. The method includes setting a maximum Internet protocol multicast bandwidth for the access points, receiving an admissions control request from a client at one of the access points, and determining whether the admissions control request from the client is for an admitted or unadmitted multicast stream at the access point. The access point is responsive to the admissions control request for the admitted multicast stream by servicing the admitted multicast stream and to the admissions control request for the unadmitted multicast stream by servicing the unadmitted multicast stream where the bandwidth required for the unadmitted multicast stream, plus that portion of the access point bandwidth currently used for all existing downlink multicast streams, does not exceed the maximum internet protocol multicast bandwidth for the access point.

Abstract: The present application relates to a method and apparatus for excavating soil from the ground to form a hole or trench. The tool is provided with a plurality of excavation members which are caused to penetrate the ground in order that soil may be excavated. The direction of excavation of the tool may be adjusted by the use of one or more steering members (10), the or each steering member comprising a steering element (11) which is disposed, or is operable to be disposed, such that the initial point of contact of the steering element with the ground allows the direction of excavation of the tool to be adjusted. Provides a simple, but effective, mechanical means to adjust the direction of excavation. The steering element may comprise a plate which is angled such that at the point of contact with the ground, the steering members may gently divert the grab in the desired direction. Thus, in this way, any deviation in the direction of excavation can be corrected or at least countered.

Abstract: A compound of the formula (1) or a pharmaceutically-acceptable salt, or pro-drug thereof; wherein, for example, Z is CH or nitrogen, R4 and R5 together are either —S—C(R6)?C(R7)— or —C(R7)?C(R6)—S—; R6 and R7 are independently selected from hydrogen, halo, nitro, cyano, hydroxy, fluoromethyl, difluoromethyl, trifluoromethyl, trifluoromethoxy, carboxy and carbamoyl; A is phenylene or heteroarylene; n is 0, 1 or 2; r is 1 or 2; R1 is halo, cyano or carboxy; Y is selected from —C(O)R2, —C(O)OR2, —C(O)NR2R3, -(1-4C)alkyl [optionally substituted] -(2-4C)alkenyl, —SO2NR2R3, and —S(O)cR2 (wherein c is 0, 1 or 2); R2 and R3 are independently selected from hydrogen, —O(1-4C)alkyl, —S(1-4C)alkyl, —N(1-4C)alkyl, heterocyclyl, aryl, and (1-4C)alkyl [optionally substituted]; possess glycogen phosphorylase inhibitory activity and accordingly have value in the treatment of disease states associated with increased glycogen phosphorylase activity.

Abstract: A wireless authentication protocol. Access to a network is managed by providing a challenge-handshake protocol within the Extensible Authentication Protocol for authentication between a client and the network.

Abstract: Heterocyclic amides of formula (1) wherein: is a single or double bond; A is phenylene or heteroarylene; m is 0, 1 or 2; n is 0, 1 or 2; R1 is selected from for example halo, nitro, cyano, hydroxy, carboxy; r is 1 or 2; Y is —NR2R3 or —OR3; R2 and R3 are selected from for example hydrogen, hydroxy, aryl, heterocyclyl and C1-4alkyl(optionally substituted by 1 or 2 R8 groups); R4 is selected from for example hydrogen, halo, nitro, cyano, hydroxy, C1-4alkyl, and C1-4alkanoyl; R8 is selected from for example hydroxy, —COCOOR9, —C(O)N(R9)(R9), —NHC(O)R9, (R9)(R10)N— and —COOR9; R9 and R10 are selected from for example hydrogen, hydroxy, C1-4alkyl (optionally substituted by 1 or 2 R13); R13 is selected from hydroxy, halo, trihalomethyl and C1-4alkoxy; or a pharmaceutically acceptable salt or pro-drug thereof; possess glycogen phosphorylase inhibitory activity and accordingly have value in the treatment of disease states associated with increased glycogen phosphorylase activity.

Abstract: Heterocyclic amides of formula (1) wherein: Z is CH or nitrogen; R4 and R5 together are either —S—C(R6)?C(R7)— or —C(R7)?C(R6)—S—; R6 and R7 are selected from for example hydrogen, halo, C1-4alkyl, and C1-4alkanoyl; A is phenylene or heteroarylene; n is 0, 1 or 2; R1 is selected from for example halo, nitro, cyano, hydroxy, carboxy; r is 1 or 2; Y is —NR2R3 or —OR3; R2 and R3 are selected from for example hydrogen, hydroxy, aryl, heterocyclyl and C1-4alkyl(optionally substituted by 1 or 2 R8 groups); R4 is selected from for example hydrogen, halo, nitro, cyano, hydroxy, C1-4alkyl, and C1-4alkanoyl; R8 is selected from for example hydroxy, —COCOOR9, —C(O)N(R9)(R10), —NHC(O)R9, (R9)(R10)N— and —COOR9; R9 and R10 are selected from for example hydrogen, hydroxy, C1-4alkyl (optionally substituted by 1 or 2 R13); R13 is selected from hydroxy, halo, trihalomethyl and C1-4alkoxy; or a pharmaceutically acceptable salt or pro-drug thereof; possess glycogen phosphorylase inhibitory activity and accordingly have va

Abstract: A compound of the formula (1) or a pharmaceutically-acceptable salt, or pro-drug thereof; (1) wherein, for example, R4 is halo or (1-4C)alkyl; A is phenylene or heteroarylene; n is 0, 1 or 2; m is 0, 1 or 2; R1 is halo, cyano or carboxy; R2 is for example methyl; R3 is for example selected from halo(1-4C)alkyl, dihalo(1-4C)alkyl, trifluoromethyl, hydroxy(1-4C)alkyl, dihydroxy(2-4C)alkyl, trihydroxy(3-4C)alkyl, cyano(1-4C)alkyl (optionally substituted on alkyl with hydroxy), (1-4C)alkoxy(1-4C)alkyl, (1-4C)alkoxy(1-4C)alkoxy(1-4C)alkyl, di[(1-4C)alkoxy](1-4C)alkyl, (hydroxy)[(1-4C)alkoxy](1-4C)alkyl; possess glycogen phosphorylase inhibitory activity and accordingly have value in the treatment of disease states associated with increased glycogen phosphorylase activity. Processes for the manufacture of compounds and pharmaceutical compositions containing them are described.