Patents by Inventor Stuart Pearson

Stuart Pearson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • C-anilinoquinazoline compounds and their use in treating cancer
    Patent number: 10829479
    Abstract: The invention concerns compounds of Formula (I): or pharmaceutically acceptable salts thereof, wherein R1, R2, R3 and R4 have any of the meanings hereinbefore defined in the description; process for their preparation; pharmaceutical compositions containing them and their use in treating KIT mediated diseases.
    Type: Grant
    Filed: March 5, 2019
    Date of Patent: November 10, 2020
    Assignee: AstraZeneca AB
    Inventors: Jason Kettle, Stuart Pearson, Martin Packer, James Smith, Tudor Grecu
  • C5-anilinoquinazoline Compounds and Their Use in Treating Cancer
    Publication number: 20190263787
    Abstract: The invention concerns compounds of Formula (I): or pharmaceutically acceptable salts thereof, wherein R1, R2, R3 and R4 have any of the meanings hereinbefore defined in the description; process for their preparation; pharmaceutical compositions containing them and their use in treating KIT mediated diseases.
    Type: Application
    Filed: March 5, 2019
    Publication date: August 29, 2019
    Inventors: Jason Kettle, Stuart Pearson, Martin Packer, James Smith, Tudor Grecu
  • C5-anilinoquinazoline compounds and their use in treating cancer
    Patent number: 10273227
    Abstract: The invention concerns compounds of Formula (I): or pharmaceutically acceptable salts thereof, wherein R1, R2, R3 and R4 have any of the meanings hereinbefore defined in the description; process for their preparation; pharmaceutical compositions containing them and their use in treating KIT mediated diseases.
    Type: Grant
    Filed: April 26, 2018
    Date of Patent: April 30, 2019
    Assignee: AstraZeneca AB
    Inventors: Jason Kettle, Stuart Pearson, Martin Packer, James Smith
  • C5-ANILINOQUINAZOLINE COMPOUNDS AND THEIR USE IN TREATING CANCER
    Publication number: 20180312490
    Abstract: The invention concerns compounds of Formula (I): or pharmaceutically acceptable salts thereof, wherein R1, R2, R3 and R4 have any of the meanings hereinbefore defined in the description; process for their preparation; pharmaceutical compositions containing them and their use in treating KIT mediated diseases.
    Type: Application
    Filed: April 26, 2018
    Publication date: November 1, 2018
    Inventors: Jason KETTLE, Stuart Pearson, Martin Packer, James Smith, Tudor Grecu
  • Lightweight four-stroke engine
    Publication number: 20050145232
    Abstract: A lightweight, four stroke engine includes a crankcase enclosure and at least one piston assembly disposed within the crankcase enclosure. The piston assembly cooperates with the crankcase enclosure to provide an internal pressure to the crankcase enclosure which varies between a positive and a negative pressure. An air intake assembly is operatively coupled to a first section of the engine and the crankcase enclosure, the air intake assembly including at least one air conduit configured to provide non-combustive air flow from the first section of the engine to the crankcase enclosure of the engine. At least one valve is disposed within the air intake system, the valve being configured to restrict air flow from the crankcase enclosure when positively pressurized and to allow airflow into the crankcase enclosure when negatively pressurized.
    Type: Application
    Filed: March 3, 2005
    Publication date: July 7, 2005
    Inventors: William White, Stuart Pearson
  • 2,4,DI (hetero-) arylamino (-oxy) -5-substituted pyrimidines as antineoplastic agents
    Publication number: 20050090515
    Abstract: Pyrimidine derivatives of formula (I) wherein Q1, Q2, G and R1 are as defined within; and pharmaceutically acceptable salts and in vivo hydrolysable esters thereof are described. Processes for their manufacture, pharmaceutical compositions and their use as cyclin-dependent serine/threonine kinase (CDK) and focal adhesion kinase (FAK) inhibitors are also described.
    Type: Application
    Filed: November 24, 2004
    Publication date: April 28, 2005
    Inventors: Elizabeth Pease, Emma Williams, Robert Bradbury, Stuart Pearson