Abstract: Disclosed are techniques for displaying AR elements on a display system of a construction machine. A position of the construction machine in a world reference frame is detected. An orientation of the construction machine is detected. A position of an operator of the construction machine in a machine reference frame is detected. A position of the operator in the world reference frame is determined based on the position of the operator in the machine reference frame, the position of the construction machine in the world reference frame, and the orientation of the construction machine. The AR elements are generated based on the position of the operator in the world reference frame and a position of the display system in the world reference frame. The AR elements are then displayed on the display system.

Abstract: Disclosed are techniques for displaying AR elements on a display system of a construction machine. A position of the construction machine in a world reference frame is detected. An orientation of the construction machine is detected. A position of an operator of the construction machine in a machine reference frame is detected. A position of the operator in the world reference frame is determined based on the position of the operator in the machine reference frame, the position of the construction machine in the world reference frame, and the orientation of the construction machine. The AR elements are generated based on the position of the operator in the world reference frame and a position of the display system in the world reference frame. The AR elements are then displayed on the display system.

Abstract: An apparatus for providing navigational information associated with locations of objects includes an imaging device configured to acquire image data, a visual display coupled to the imaging device and configured to display the image data, a position measuring device configured to determine position information associated with the imaging device, and an orientation device configured to determine orientation information associated with the imaging device. The apparatus may also include a rendering system coupled to the visual display, the position measuring device, and the orientation device. The rendering system may be configured to determine image coordinates associated with a location of an object and provide a navigational graphic on the visual display oriented relative to the image coordinates.

Abstract: An apparatus for providing navigational information associated with locations of objects includes an imaging device configured to acquire image data, a visual display coupled to the imaging device and configured to display the image data, a position measuring device configured to determine position information associated with the imaging device, and an orientation device configured to determine orientation information associated with the imaging device. The apparatus may also include a rendering system coupled to the visual display, the position measuring device, and the orientation device. The rendering system may be configured to determine image coordinates associated with a location of an object and provide a navigational graphic on the visual display oriented relative to the image coordinates.

Abstract: An apparatus for providing navigational information associated with locations of objects includes an imaging device configured to acquire image data, a visual display coupled to the imaging device and configured to display the image data, a position measuring device configured to determine position information associated with the imaging device, and an orientation device configured to determine orientation information associated with the imaging device. The apparatus may also include a rendering system coupled to the visual display, the position measuring device, and the orientation device. The rendering system may be configured to determine image coordinates associated with a location of an object and provide a navigational graphic on the visual display oriented relative to the image coordinates.

Abstract: An apparatus for providing navigational information associated with locations of objects includes an imaging device configured to acquire image data, a visual display coupled to the imaging device and configured to display the image data, a position measuring device configured to determine position information associated with the imaging device, and an orientation device configured to determine orientation information associated with the imaging device. The apparatus may also include a rendering system coupled to the visual display, the position measuring device, and the orientation device. The rendering system may be configured to determine image coordinates associated with a location of an object and provide a navigational graphic on the visual display oriented relative to the image coordinates.

Abstract: The present invention pertains to certain ketones and reduced ketones and derivatives thereof which, inter alia, inhibit osteoclast survival, formation, and/or activity; and/or inhibit bone resorption, and more particularly to compounds of the formulae: (1) (2) wherein: Ar1 is independently a biphenyl, phenanthryl, fluorenyl, or carbazolyl, and is optionally substituted; Ralk is independently a C2-10alkylene group, and is optionally substituted; —ORO, if present, is independently —OH or —ORK; —ORK, if present, is independently selected from: —O—RK1; —O—C(?O)RK2; —O—C(?O)ORK3; —O—S(?O)2ORK4; Q is independently —OH or —OROT; wherein: —OROT, if present, is independently selected from: —O—RE1; —O—C(?O)—RE2; —O—C(?O)—O—RE3; —O—C(?O)—O—SO3RE4; —O—C(?O)—O—(CH2)n—COORE5; —O—C(?O)—(CH2)n—NRN1RN2; —O—C(?O)—(CH2)n—NH—C(?O)RE6; —O—C(?O)—(CH2)n—C(?O)—NRN3RN4; —O—P(?O)(ORE7)(ORE8); —O—RPA; RPA, if present, is an organic group which incorporates a phosphonic acid group; with the proviso A that if —OROT is —O—RE1, then RE1 i

Abstract: Provided are genetic methods and materials for assessing bone mineral density (BMD) and determining the susceptibility of an individual to a disorder which is associated with a low level of BMD, the method comprising use of chloride channel 7 (Clcn7) marker. The methods may be used e.g. for diagnosis of osteoporosis. Preferred Clcn7 markers at specified positions are disclosed.

Abstract: The present invention pertains to cannabinoid (CB) receptor inverse agonists and neutral antagonists, and especially CB1 and CB2 inverse agonists and neutral antagonists; such as, for example, certain pyrazole compounds; their use in the inhibition of osteoclasts (for example, the inhibition of the survival, formation, and/or activity of osteoclasts), and/or in the inhibition of bone resorption; their use in connection with treatment of bone disorders, such as conditions mediated by osteoclasts (e.g., increased osteoclast activity) and/or characterised by (e.g., increased) bone resorption, such as osteoporosis (e.g., osteoporosis not associated with inflammation; e.g., osteoporosis associated with a genetic predisposition, sex hormone deficiency, or ageing), cancer associated bone disease, and Paget's disease of bone.

Abstract: The invention provides an agent for preventing or treating arthritis, a cartilage protecting agent, a joint destruction inhibitor and a synovial membrane growth inhibitor comprising an anti-FGF-8 neutralizing antibody as an active ingredient, as well as a diagnostic agent of arthritis comprising an anti-FGF-8 antibody as an active ingredient and a method for judging arthritis using the antibody.