Patents by Inventor Stuart Robert ABERCROMBIE

Stuart Robert ABERCROMBIE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240042147
    Abstract: A dry powder inhaler includes an inhalation channel connected to a mouthpiece, a container for storing a powdered medicament, a de-agglomerator with a vortex chamber located at an end of the inhalation channel, a metering device including a shuttle having a dosing recess. The shuttle is movable between a filling position, in which the dosing recess is in alignment with an opening of the container, and an inhalation position, in which the dosing recess is in alignment with the vortex chamber. The opening of the container is elongated along a major axis and the dosing recess is elongated along a main axis and, when the shuttle is in the filling position, an edge of the opening of the container encloses the dosing recess.
    Type: Application
    Filed: August 2, 2023
    Publication date: February 8, 2024
    Inventors: Marco DI CASTRI, Stuart Robert ABERCROMBIE, Donal Joseph TAYLOR
  • Patent number: 11707610
    Abstract: Ingestible devices can directly deliver therapeutic agents to desired tissue(s) of the GI tract of a subject, such as the submucosa, the mucosa, and/or the mucus layer of the GI tract, and methods of using the same. The ingestible devices can deliver therapeutic agents in a safe, effective, and reliable manner. The disclosure also provides pharmaceutical compositions for use in methods of treating a disease or condition in a subject in need thereof.
    Type: Grant
    Filed: December 11, 2020
    Date of Patent: July 25, 2023
    Assignee: BIORA THERAPEUTICS, INC.
    Inventors: Jeffrey A. Shimizu, Mitchell Lawrence Jones, Mark Sasha Drlik, Iman Niknia, Nathan John Muller, Tuyen Nguyen, Christopher Loren Wahl, Edward Mudge, Nicholas Mark Salt, Nia Eleri Stevens, Stuart Robert Abercrombie, Christopher Ian Bunce, Ryan Elliott Jones, Kevin Howe, Pejman Rahimian, Nelson Quintana
  • Publication number: 20230149315
    Abstract: Ingestible devices can directly deliver therapeutic agents to desired tissue(s) of the GI tract of a subject, such as the submucosa, the mucosa, and/or the mucus layer of the GI tract, and methods of using the same. The ingestible devices can deliver therapeutic agents in a safe, effective, and reliable manner. The disclosure also provides pharmaceutical compositions for use in methods of treating a disease or condition in a subject in need thereof.
    Type: Application
    Filed: December 11, 2020
    Publication date: May 18, 2023
    Inventors: Jeffrey A. SHIMIZU, Mitchell Lawrence JONES, Mark Sasha DRLIK, Iman NIKNIA, Nathan John MULLER, Tuyen NGUYEN, Christopher Loren WAHL, Edward MUDGE, Nicholas Mark SALT, Nia Eleri STEVENS, Stuart Robert ABERCROMBIE, Christopher Ian BUNCE, Ryan Elliott JONES, Kevin David HOWE, Pejman RAHIMIAN, Nelson QUINTANA
  • Publication number: 20230023414
    Abstract: This disclosure features methods and devices for treating diseases with orally-delivered biotherapeutics.
    Type: Application
    Filed: November 19, 2019
    Publication date: January 26, 2023
    Inventors: Jeffrey A. Shimizu, Mitchell Lawrence Jones, Mark Sasha Drlik, Iman Niknia, Nathan John Muller, Tuyen Nguyen, Christopher Loren Wahl, Edward Mudge, Nicholas Mark Salt, Nia Eleri Stevens, Stuart Robert Abercrombie, Christopher Ian Bunce, Nelson Quintana
  • Publication number: 20230017603
    Abstract: Ingestible devices can directly deliver therapeutic agents to desired tissue(s) of the GI tract of a subject, such as the submucosa, the mucosa, and/or the mucus layer of the GI tract, and methods of using the same. The ingestible devices can deliver therapeutic agents in a safe, effective, and reliable manner. The disclosure also provides pharmaceutical compositions for use in methods of treating a disease or condition in a subject in need thereof.
    Type: Application
    Filed: September 15, 2022
    Publication date: January 19, 2023
    Inventors: Jeffrey A. SHIMIZU, Mitchell Lawrence JONES, Mark Sasha DRLIK, Iman NIKNIA, Nathan John MULLER, Tuyen NGUYEN, Christopher Loren WAHL, Edward MUDGE, Nicholas Mark SALT, Nia Eleri STEVENS, Stuart Robert ABERCROMBIE, Christopher Ian BUNCE, Ryan Elliott JONES, Kevin HOWE, Pejman RAHIMIAN, Nelson QUINTANA
  • Patent number: 11439802
    Abstract: A method of treating a disease or condition in a subject in need thereof is disclosed. The method comprising: trans-epithelially administering a dispensable substance to the gastrointestinal (GI) tract of the subject by orally administering an ingestible device comprising the dispensable substance to the subject. The ingestible device is configured for trans-epithelial delivery of the dispensable substance to the GI tract of the subject and the dispensable substance comprises a pharmaceutical formulation comprising a therapeutically effective amount of a glucagon receptor agonist or a glucagon-like peptide-1 (GLP-1) receptor agonist. The ingestible device releases the dispensable substance as at least one jet to a desired location of the GI tract of the subject.
    Type: Grant
    Filed: May 13, 2021
    Date of Patent: September 13, 2022
    Assignee: Biora Therapeutics, Inc.
    Inventors: Jeffrey A. Shimizu, Mitchell Lawrence Jones, Mark Sasha Drlik, Iman Niknia, Nathan John Muller, Tuyen Nguyen, Christopher Loren Wahl, Edward Mudge, Nicholas Mark Salt, Nia Eleri Stevens, Stuart Robert Abercrombie, Christopher Ian Bunce, Nelson Quintana
  • Publication number: 20220249814
    Abstract: This disclosure features methods and devices for treating diseases with orally-delivered biotherapeutics.
    Type: Application
    Filed: November 19, 2019
    Publication date: August 11, 2022
    Inventors: Jeffrey A. Shimizu, Mitchell Lawrence Jones, Mark Sasha Drlik, Iman Niknia, Nathan John Muller, Tuyen Nguyen, Christopher Loren Wahl, Edward Mudge, Nicholas Mark Salt, Nia Eleri Stevens, Stuart Robert Abercrombie, Christopher Ian Bunce, Nelson Quintana
  • Publication number: 20210283385
    Abstract: An ingestible device, includes a storage reservoir configured to store a dispensable substance and a pressurized chamber configured so that, when a restraining force is removed from the pressurized chamber, the dispensable substance exits the ingestible device via openings in the ingestible device.
    Type: Application
    Filed: May 13, 2021
    Publication date: September 16, 2021
    Inventors: Jeffrey A. Shimizu, Mitchell Lawrence Jones, Mark Sasha Drlik, Iman Niknia, Nathan John Muller, Tuyen Nguyen, Christopher Loren Wahl, Edward Mudge, Nicholas Mark Salt, Nia Eleri Stevens, Stuart Robert Abercrombie, Christopher Ian Bunce, Nelson Quintana
  • Patent number: 11007356
    Abstract: An ingestible device, includes a storage reservoir configured to store a dispensable substance and a pressurized chamber configured so that, when a restraining force is removed from the pressurized chamber, the dispensable substance exits the ingestible device via openings in the ingestible device.
    Type: Grant
    Filed: September 17, 2020
    Date of Patent: May 18, 2021
    Assignee: Progenity, Inc.
    Inventors: Jeffrey A. Shimizu, Mitchell Lawrence Jones, Mark Sasha Drlik, Iman Niknia, Nathan John Muller, Tuyen Nguyen, Christopher Loren Wahl, Edward Mudge, Nicholas Mark Salt, Nia Eleri Stevens, Stuart Robert Abercrombie, Christopher Ian Bunce, Nelson Quintana
  • Publication number: 20210038872
    Abstract: An ingestible device, includes a storage reservoir configured to store a dispensable substance and a pressurized chamber configured so that, when a restraining force is removed from the pressurized chamber, the dispensable substance exits the ingestible device via openings in the ingestible device.
    Type: Application
    Filed: September 17, 2020
    Publication date: February 11, 2021
    Inventors: Jeffrey A. Shimizu, Mitchell Lawrence Jones, Mark Sasha Drlik, Iman Niknia, Nathan John Muller, Tuyen Nguyen, Christopher Loren Wahl, Edward Mudge, Nicholas Mark Salt, Nia Eleri Stevens, Stuart Robert Abercrombie, Christopher Ian Bunce, Nelson Quintana
  • Patent number: 10646265
    Abstract: Disclosed herein is an apparatus for cooling a sterile liquid for use in cryotherapy, the apparatus comprising: a first chamber (202) adapted to receive a removable container (201) of sterile liquid and a fluid port for receiving a fluid for applying, in use, pressure to a received removable container (201); and a second chamber (203) comprising a cooler; wherein the first chamber (202) is arranged to be in thermal conductivity with the second chamber (203) such that, in use, the contents of the first chamber (202) are cooled by the cooler of the second chamber (203). Advantageously, embodiments provide a system, heat exchanger unit within the system and method for supplying a sterilised working fluid to a catheter system for cryotherapy, the working fluid being supplied at a desired and easily controllable temperature and flow rate.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: May 12, 2020
    Assignee: Cryotherapeutics GmbH
    Inventors: Stuart Robert Abercrombie, Duncan Aleck Bishop, Symon Cotton, Richard Day, Sylvain Bruno Jamais, Simon Karger, Andrew Lintott, Nathan Wrench
  • Publication number: 20200054558
    Abstract: An aerosol preparation assembly includes an entrainment chamber defining an entrainment volume. The entrainment chamber includes a gas inlet port, an aerosol inlet port and an outlet port. The entrainment chamber is configured such that a velocity of a flow of a gas within the entrainment volume is less than a velocity of the flow of the gas within the gas inlet port. The entrainment chamber is configured such that at least a portion of inlet aerosol is entrained into the flow of the gas within the entrainment volume to produce an entrained aerosol flow at the outlet port. The particle selection chamber is configured to receive the entrained aerosol flow and produce an outlet aerosol flow. The particle selection chamber and nozzle are collectively configured such that a volumetric median diameter of the outlet aerosol flow is less than a volumetric median diameter of the inlet aerosol.
    Type: Application
    Filed: March 20, 2019
    Publication date: February 20, 2020
    Applicant: PARION SCIENCES, INC.
    Inventors: Paul BOUCHER, Richard BOUCHER, Brian M. BUTTON, Michael R. JOHNSON, James B. FINK, Anthony J. HICKEY, Tomas NAVRATIL, William Robert THELIN, Stuart Robert ABERCROMBIE, Philip Jerome DRIVER, Mark Jeffrey EDHOUSE, Nicholas O. HEIJNE, Donal Joseph TAYLOR, Jonathan Hugh WILKINS
  • Publication number: 20190275269
    Abstract: The present invention relates to a dry powder inhaler for administering a medicament via oral inhalation route to a subject. Particularly, the dry powder inhaler according to present invention is suitable for delivering accurate doses of a medicament in different ranges of inspiratory capacity of the subject.
    Type: Application
    Filed: May 23, 2019
    Publication date: September 12, 2019
    Applicant: GLENMARK PHARMACEUTICALS LIMITED
    Inventors: Ulhas DHUPPAD, Rachel Rachel STRIEBIG, Scott Alexander LEWIS, Matthew David ALLEN, Lai Chiu TANG, Stuart Robert ABERCROMBIE, John William Sanford HALE, Thomas Stephen COLLINGS
  • Patent number: 10357622
    Abstract: The present invention relates to a dry powder inhaler for administering a medicament via oral inhalation route to a subject. Particularly, the dry powder inhaler according to present invention is suitable for delivering accurate doses of a medicament in different ranges of inspiratory capacity of the subject.
    Type: Grant
    Filed: December 23, 2014
    Date of Patent: July 23, 2019
    Assignee: GLENMARK PHARMACEUTICALS LIMITED
    Inventors: Ulhas Dhuppad, Rachel Victoria Striebig, Scott Alexander Lewis, Matthew David Allen, Lai Chiu Tang, Stuart Robert Abercrombie, John William Sanford Hale, Thomas Stephen Collings
  • Publication number: 20160361106
    Abstract: Disclosed herein is an apparatus for cooling a sterile liquid for use in cryotherapy, the apparatus comprising: a first chamber (202) adapted to receive a removable container (201) of sterile liquid and a fluid port for receiving a fluid for applying, in use, pressure to a received removable container (201); and a second chamber (203) comprising a cooler; wherein the first chamber (202) is arranged to be in thermal conductivity with the second chamber (203) such that, in use, the contents of the first chamber (202) are cooled by the cooler of the second chamber (203). Advantageously, embodiments provide a system, heat exchanger unit within the system and method for supplying a sterilised working fluid to a catheter system for cryotherapy, the working fluid being supplied at a desired and easily controllable temperature and flow rate.
    Type: Application
    Filed: December 15, 2014
    Publication date: December 15, 2016
    Applicant: CRYOTHERAPEUTICS GMBH
    Inventors: Stuart Robert Abercrombie, Duncan Aleck Bishop, Symon Cotton, Richard Day, Sylvain Bruno Jamais, Simon Karger, Andrew Lintott, Nathan Wrench
  • Publication number: 20150174346
    Abstract: The present invention relates to a dry powder inhaler for administering a medicament via oral inhalation route to a subject. Particularly, the dry powder inhaler according to present invention is suitable for delivering accurate doses of a medicament in different ranges of inspiratory capacity of the subject.
    Type: Application
    Filed: December 23, 2014
    Publication date: June 25, 2015
    Inventors: Ulhas DHUPPAD, Rachel Victoria STRIEBIG, Scott Alexander LEWIS, Matthew David ALLEN, Lai Chiu TANG, Stuart Robert ABERCROMBIE, John William Sanford HALE, Thomas Stephen COLLINGS
  • Publication number: 20150150803
    Abstract: An aerosol preparation assembly includes an entrainment chamber defining an entrainment volume. The entrainment chamber includes a gas inlet port, an aerosol inlet port and an outlet port. The entrainment chamber is configured such that a velocity of a flow of a gas within the entrainment volume is less than a velocity of the flow of the gas within the gas inlet port. The entrainment chamber is configured such that at least a portion of inlet aerosol is entrained into the flow of the gas within the entrainment volume to produce an entrained aerosol flow at the outlet port. The particle selection chamber is configured to receive the entrained aerosol flow and produce an outlet aerosol flow. The particle selection chamber and nozzle are collectively configured such that a volumetric median diameter of the outlet aerosol flow is less than a volumetric median diameter of the inlet aerosol.
    Type: Application
    Filed: January 9, 2015
    Publication date: June 4, 2015
    Applicant: PARION SCIENCES, INC.
    Inventors: Paul BOUCHER, Richard BOUCHER, Brian M. BUTTON, Michael R. JOHNSON, James B. FINK, Anthony J. HICKEY, Tomas NAVRATIL, William Robert THELIN, Stuart Robert ABERCROMBIE, Philip Jerome DRIVER, Mark Jeffrey EDHOUSE, Nicholas O. HEIJNE, Donal Joseph TAYLOR, Jonathan Hugh WILKINS
  • Patent number: 8945605
    Abstract: An aerosol preparation assembly includes an entrainment chamber defining an entrainment volume. The entrainment chamber includes a gas inlet port, an aerosol inlet port and an outlet port. The entrainment chamber is configured such that a velocity of a flow of a gas within the entrainment volume is less than a velocity of the flow of the gas within the gas inlet port. The entrainment chamber is configured such that at least a portion of inlet aerosol is entrained into the flow of the gas within the entrainment volume to produce an entrained aerosol flow at the outlet port. The particle selection chamber is configured to receive the entrained aerosol flow and produce an outlet aerosol flow. The particle selection chamber and nozzle are collectively configured such that a volumetric median diameter of the outlet aerosol flow is less than a volumetric median diameter of the inlet aerosol.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: February 3, 2015
    Assignee: Parion Sciences, Inc.
    Inventors: Paul Boucher, Richard Boucher, Brian M. Button, Michael R. Johnson, James B. Fink, Anthony J. Hickey, Tomas Navratil, William Robert Thelin, Stuart Robert Abercrombie, Philip Jerome Driver, Mark Jeffrey Edhouse, Nicholas O. Heijne, Donal Joseph Taylor, Jonathan Hugh Wilkins
  • Publication number: 20140158127
    Abstract: An apparatus can include a nasal cannula assembly, which includes a face piece. The face piece includes a plenum portion and a nasal interface portion. The plenum portion is configured to be coupled to a supply line and defines a flow path configured to receive an aerosol flow from the supply line. The nasal interface portion includes a first delivery protrusion and a second delivery protrusion. The first delivery protrusion is configured to convey a first portion of the aerosol flow to a first nostril, and the second delivery protrusion is configured to deliver a second portion of the aerosol flow to a second nostril. The plenum portion includes a sidewall having a curved surface configured to redirect the second portion of the aerosol flow towards the second delivery protrusion. The sidewall is configured to isolate the flow path from a volume downstream from the second delivery protrusion.
    Type: Application
    Filed: December 6, 2013
    Publication date: June 12, 2014
    Applicant: PARION SCIENCES, INC.
    Inventors: Paul BOUCHER, Brian M. BUTTON, James B. FINK, Anthony J. HICKEY, Tomas NAVRATIL, Stuart Robert ABERCROMBIE, Michael Richard BURCHER, Mark Jeffrey EDHOUSE, Jamie Alan GREENWOOD, Emma Jane HASLER, Guy Conwyn Julian MOSELEY, David William SMITH, Donal Joseph TAYLOR, Jonathan Hugh WILKINS