Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of HPK1, and the treatment of HPK1-mediated disorders.

Abstract: A system for power reduction during vehicle access. A memory storing instructions executable by a processor includes instructions to receive an access message by a target vehicle, authenticate the access message, and determine either an occurrence of a power-saving condition or a non-occurrence of the power-saving condition. The instructions include activating a greeting indicator upon authentication of the access message and determining the non-occurrence of the power-saving condition, and determining not to activate the greeting indicator upon authentication of the access message and determining the occurrence of the power-saving condition.

Abstract: A computer includes a processor and a memory storing instructions executable by the processor to select a scanning rate for a first sensor of a vehicle based on at least one of data related to a current time or data related to a location of the vehicle; instruct the first sensor to run at the selected scanning rate; in response to receiving data from the first sensor indicating a newly present object, turn on a second sensor; and then record data from the second sensor. The second sensor has a higher power draw than the first sensor.

Abstract: A vehicle is provided that includes a vehicle body, a plurality of RF signal receivers located at a plurality of locations within the vehicle, an RF signal transmitter configured to be located on a pet for transmitting an RF signal, and a controller for processing the RF signal received by each of the plurality of RF signal receivers and determining a location of the pet based on the received RF signals, wherein the controller generates an output based on the location of the pet and controls at least one vehicle function based on the output.

Abstract: A window breaker tool for use on a vehicle includes a body having a handle to enable a user to grip the tool, a glass breaker member extending from the handle configured to contact a glass window with force to break the glass window, and an accelerometer operatively coupled to the body to sense acceleration during impact and generate a signature signal. The tool also includes an RF signal communication device located on the tool for communicating with a plurality of RF signal communication devices on the vehicle to determine a location of the tool relative to the vehicle, wherein the RF signal communication device communicates with a controller for processing the signature signal and determining whether the signature signal is indicative of the tool in use to break a window, and wherein the controller further determines the tool is within the vehicle based on the location and outputs an alert signal.

Abstract: An automated projector image optimization (APIO) system for a vehicle having a control system is provided. The APIO system includes a projector configured to display an image, a processor configured to be electrically connected to the control system, and a memory having instructions that, when executed by the processor, cause the processor to perform operations including receiving a user input corresponding to a display surface, determining a preferred orientation of the projector relative to the display surface, and employing the control system to move the vehicle so that the projector is in the preferred orientation.

Abstract: Some embodiments of the present disclosure relate to an additively manufactured transport structure. The transport structure includes cavities into which components that use an external interface are inserted. A plurality of components are assembled and integrated into the vehicle. In an embodiment, the components and frame are modular, enabling reparability and replacement of single parts in the event of isolated failures.

Abstract: A computer includes a processor and a memory, and the memory stores instructions executable by the processor to receive range data from a range sensor of a vehicle, detect a person in proximity to the vehicle based on the range data, activate a camera of the vehicle upon detecting the person, set a parameter of one of the camera or a facial recognition algorithm based on the range data of the person, and perform the facial recognition algorithm on the person using data from the camera.

Abstract: MECP2 EXPRESSION CASSETTES. The present invention provides nucleic acid molecules comprising a MeCP2 expression cassette, the expression cassette comprising, in operable linkage from 5? to 3?: a 5? transcriptional control region comprising a promoter capable of driving transcription in neural cells; an open reading frame encoding a MeCP2 protein; translation control signals; a 3? untranslated region (3?UTR) comprising one or more of: (i) a binding site for mir-22; (ii) a binding site for mir-19; (iii) a binding site for miR-132; (iv) a binding site for miR124; and (v) an AU-rich element; and transcriptional termination signals; wherein the MeCP2 expression cassette is not more than about 5 kb in length. The invention further provides viral vectors, especially vectors derived from adeno-associated virus (AAV), for use in therapeutic delivery of such expression cassettes.

Abstract: A vehicle lighting system is disclosed. The vehicle lighting system may include a display unit configured to operate in a plurality of display modes. The display unit may be mounted on a vehicle rear top portion. The vehicle lighting system may further include a processor that may be configured to obtain trigger event information associated with the display unit. Based on the trigger event information, the processor may select a display mode from the plurality of display modes, and may activate the display unit responsive to the selection.

Abstract: The disclosure describes systems and methods for controlling a heating element of a window of a vehicle. The systems and methods include capturing an image of the window with a camera of the vehicle. The image is analyzed to determine a state of the window and the heating element is controlled based on the state of the window.

Abstract: A system and method to manage charging priority for at least one accessory includes the steps of: providing one or more charging stations for the at least one accessory, monitoring vehicle power status, and monitoring accessory charging status. Additionally, the allocation of power supplied to the one or more charging stations is managed based on priority requirements as determined per each accessory.

Abstract: A vehicle includes a cabin interior, a powered door having an actuator for moving the door between closed and open positions, interior sensors sensing position or movement of an occupant in the cabin interior, and exterior sensors sensing a passerby proximate to the vehicle. The vehicle includes a controller determining an occupant intending to exit the vehicle via the door based on the interior sensors and determining a passerby passing by the door in an open position using the at least one exterior sensors. The controller controls the actuator to open the door when the occupant is intended to exit the vehicle and at least partially closes the door when a passerby is detected passing by the vehicle door and an occupant is determined not to be exiting the vehicle. The controller controls the actuator to open the door further when the passerby is determined to pass by the door.

Abstract: Some embodiments of the present disclosure relate to an additively manufactured transport structure. The transport structure includes cavities into which components that use an external interface are inserted. A plurality of components are assembled and integrated into the vehicle. In an embodiment, the components and frame are modular, enabling reparability and replacement of single parts in the event of isolated failures.

Abstract: A vehicle includes a storage compartment, a belt conveyor located in the storage compartment and having a slat belt supported by a pair of rollers, and a shelf operatively coupled to the slat belt and configured to move between a lower stowed position within the storage compartment and an upper deployed position extending outward from the storage compartment.

Abstract: The present invention provides nucleic acid molecules comprising a MeCP2 expression cassette, the expression cassette comprising, in operable linkage from 5? to 3?: a 5? transcriptional control region comprising a promoter capable of driving transcription in neural cells; an open reading frame encoding a MeCP2 protein; translation control signals; a 3? untranslated region (3?UTR) comprising one or more of: (i) a binding site for mir-22; (ii) a binding site for mir-19; (iii) a binding site for miR-132; (iv) a binding site for miR124; and (v) an AU-rich element; and transcriptional termination signals; wherein the MeCP2 expression cassette is not more than about 5 kb in length. The invention further provides viral vectors, especially vectors derived from adeno-associated virus (AAV), for use in therapeutic delivery of such expression cassettes.

Abstract: A vehicle having park assist includes a plurality of powered closure doors, each door having an actuator for moving the door between closed and open positions, a plurality of sensors located on the vehicle for sensing objects relative to the vehicle and generating sensed signals indicative of the sensed objects, and a transceiver for communicating with a parked vehicle. The vehicle also includes a controller processing the sensed signals, determining a distance and location of the sensed objects relative to the doors, and determining a parking location for the vehicle in a garage where the closure doors are free from contact with an object in the garage when in an open position and are free of contact with powered closure doors on the parked vehicle. An output is provided to assist a driver of the vehicle to park the vehicle in the garage in the determined parking location.

Abstract: A pet bowl is provided that comprises a housing defining a water container, a proximity sensor located proximate to the water container, the proximity sensor having conductive circuitry comprising a first circuit made of a first metal and a second circuit made of a dissimilar second metal, and a controller processing signals received from the proximity sensor, the controller selectively switching the conductive circuitry between a first configuration operating as the proximity sensor to sense water contained in the container and a second configuration operating as a thermocouple to sense temperature proximate to the water container.

Abstract: A vehicle is provided that includes a vehicle body defining a cabin interior, a plurality of seats located within the cabin interior, each seat having an adjustable seat base and an adjustable seat back, a monitoring system for detecting and monitoring a pet within the cabin interior, and a controller processing signals generated by the monitoring system and determining a location of the pet based on the monitored signals, the controller further controlling at least one of the adjustable seat base and adjustable seat back of a seat based on the determined location of the pet so that the seat is configured to accommodate the pet.

Abstract: Upon identifying an authorized user approaching a vehicle, vehicle locks are controlled to permit the authorized user to access an authorized area based on a user authorization. Permitted vehicle features within the authorized area for the authorized user are identified based on the user authorization. Upon receiving a user input selecting one permitted vehicle feature, the selected permitted vehicle feature is actuated based on determining that a state of charge of a battery is above a charge threshold. Upon determining that the state of charge of the battery decreases below the charge threshold, actuation of the selected permitted vehicle feature is stopped. Then an engine is controlled to charge the battery based on the user authorization.