Patents by Inventor Stuart Schlossman

Stuart Schlossman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7658923
    Abstract: Therapeutic methods comprising administering anti-CD26 antibodies for the prevention and treatment of cancers and immune diseases associated with expressing CD26 are provided. The invention describes various types of anti-CD26 antibodies and modes of administration.
    Type: Grant
    Filed: February 16, 2007
    Date of Patent: February 9, 2010
    Assignees: Board of Regents, The University of Texas System, Dana-Farber Cancer Institute
    Inventors: Nam Hoang Dang, Chikao Morimoto, Stuart Schlossman
  • Publication number: 20070207143
    Abstract: Therapeutic methods comprising administering anti-CD26 antibodies for the prevention and treatment of cancers and immune diseases associated with expressing CD26 are provided. The invention describes various types of anti-CD26 antibodies and modes of administration.
    Type: Application
    Filed: February 16, 2007
    Publication date: September 6, 2007
    Inventors: Nam Dang, Chikao Morimoto, Stuart Schlossman
  • Patent number: 7198788
    Abstract: Therapeutic methods comprising administering anti-CD26 antibodies for the prevention and treatment of cancers and immune diseases associated with expressing CD26 are provided. The invention describes various types of anti-CD26 antibodies and modes of administration.
    Type: Grant
    Filed: May 10, 2002
    Date of Patent: April 3, 2007
    Assignees: Board of Regents, The University of Texas System, Dana-Farber Cancer Institute
    Inventors: Nam Hoang Dang, Chikao Morimoto, Stuart Schlossman
  • Publication number: 20030031665
    Abstract: Therapeutic methods comprising administering anti-CD26 antibodies for the prevention and treatment of cancers and immune diseases associated with expressing CD26 are provided. The invention describes various types of anti-CD26 antibodies and modes of administration.
    Type: Application
    Filed: May 10, 2002
    Publication date: February 13, 2003
    Inventors: Nam Hoang Dang, Chikao Morimoto, Stuart Schlossman
  • Patent number: 5432076
    Abstract: This invention concerns alteration of the interaction of PTKs and T-cell receptors. We have found that PTKs and T-cell receptors are complexed within the T-cell and the formation of this complex dictates the susceptibility of the T-cell to activation and to infection by viruses such as HIV. The nature of the interaction between the kinase and the T-cell receptor in a human is also related to the potential for cancer cell formation in that human, and to susceptibility to an autoimmune disease. Modified p56.sup.lck and transfected mammalian cells expressing the same are disclosed.
    Type: Grant
    Filed: October 1, 1993
    Date of Patent: July 11, 1995
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Christopher Rudd, Stuart Schlossman
  • Patent number: 5250431
    Abstract: This invention concerns alteration of the interaction of PTKs and T-cell receptors. We have found that PTKs and T-cell receptors are complexed within the T-cell and the formation of this complex dictates the susceptibility of the T-cell to activation and to infection by viruses such as HIV. The nature of the interaction between the kinase and the T-cell receptor in a human is also related to the potential for cancer cell formation in that human, and to susceptibility to an autoimmune disease. Modified CD4 and CD8 T cell receptors and transfected mammalian cells expressing the same are disclosed.
    Type: Grant
    Filed: September 12, 1991
    Date of Patent: October 5, 1993
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Christopher Rudd, Stuart Schlossman
  • Patent number: 4882424
    Abstract: An essentially purified antigen comprising a protein present in the T-cells of Aotus trivirgatus having molecular weights of 140 KD and 105 KD under reducing conditions and 120 KD and 90 KD under non-reducing conditions, antibodies against this antigen, and a method of using these antibodies to activate T-cells. The antibodies are able to induce T-cell activation in synergy with phorbol myristate acetate alone and with antibody against the T 11.sub.3 epitope of T 11 (CD.sub.2) antigen alone.
    Type: Grant
    Filed: May 11, 1987
    Date of Patent: November 21, 1989
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Stuart Schlossman, Chikao Morimoto, Christopher Rudd
  • Patent number: 4692405
    Abstract: A monoclonal antibody recognizing an antigenic determinant on activated human B-cells, the antigenic determinant being characteized in that it is a protein distinct from B-LAST-1 and BB-1, the antibody being substantially unreactive with unactivated human B-cells.
    Type: Grant
    Filed: March 5, 1985
    Date of Patent: September 8, 1987
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Arnold Freedman, Lee Nadler, Stuart Schlossman
  • Patent number: 4661446
    Abstract: A method of distinguishing subsets within a plurality of human cells including producing a monoclonal antibody to a non-human primate cell, contacting the monoclonal antibody with the human cells, and distinguishing the subsets on the basis of different degrees of reactivity with the monoclonal antibody.
    Type: Grant
    Filed: February 19, 1985
    Date of Patent: April 28, 1987
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Stuart Schlossman, Chikao Morimoto, Norman Letvin